Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003676 | molecular_function | nucleic acid binding |
A | 0005634 | cellular_component | nucleus |
B | 0004672 | molecular_function | protein kinase activity |
B | 0005524 | molecular_function | ATP binding |
B | 0006468 | biological_process | protein phosphorylation |
C | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
C | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
D | 0003676 | molecular_function | nucleic acid binding |
D | 0005634 | cellular_component | nucleus |
E | 0004672 | molecular_function | protein kinase activity |
E | 0005524 | molecular_function | ATP binding |
E | 0006468 | biological_process | protein phosphorylation |
F | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
F | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
G | 0003676 | molecular_function | nucleic acid binding |
G | 0005634 | cellular_component | nucleus |
H | 0004672 | molecular_function | protein kinase activity |
H | 0005524 | molecular_function | ATP binding |
H | 0006468 | biological_process | protein phosphorylation |
I | 0006357 | biological_process | regulation of transcription by RNA polymerase II |
I | 0016538 | molecular_function | cyclin-dependent protein serine/threonine kinase regulator activity |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue RC8 B 1101 |
Chain | Residue |
A | ASN907 |
B | ASP817 |
B | HIS818 |
B | ASP819 |
B | LEU866 |
A | ARG928 |
A | ARG947 |
B | ILE733 |
B | ALA754 |
B | PHE813 |
B | GLU814 |
B | TYR815 |
B | MET816 |
site_id | AC2 |
Number of Residues | 13 |
Details | binding site for residue RC8 E 1101 |
Chain | Residue |
D | ASN907 |
D | ARG928 |
D | ARG947 |
E | ILE733 |
E | ALA754 |
E | PHE813 |
E | GLU814 |
E | TYR815 |
E | MET816 |
E | ASP817 |
E | HIS818 |
E | ASP819 |
E | LEU866 |
site_id | AC3 |
Number of Residues | 14 |
Details | binding site for residue RC8 H 1101 |
Chain | Residue |
G | ASN907 |
G | ARG928 |
G | ARG947 |
H | ILE733 |
H | ALA754 |
H | PHE813 |
H | GLU814 |
H | TYR815 |
H | MET816 |
H | ASP817 |
H | HIS818 |
H | ASP819 |
H | LEU866 |
H | ASP877 |
Functional Information from PROSITE/UniProt
site_id | PS00107 |
Number of Residues | 24 |
Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. IGEGTYGQVYkAkdkdtgel..........VALK |
Chain | Residue | Details |
B | ILE733-LYS756 | |
site_id | PS00108 |
Number of Residues | 13 |
Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. FlHrDIKcsNILL |
Chain | Residue | Details |
B | PHE855-LEU867 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
B | ASP859 | |
E | ASP859 | |
H | ASP859 | |
site_id | SWS_FT_FI2 |
Number of Residues | 12 |
Details | BINDING: |
Chain | Residue | Details |
B | ILE733 | |
H | LYS756 | |
H | GLU814 | |
H | HIS1040 | |
B | LYS756 | |
B | GLU814 | |
B | HIS1040 | |
E | ILE733 | |
E | LYS756 | |
E | GLU814 | |
E | HIS1040 | |
H | ILE733 | |
Chain | Residue | Details |
B | SER889 | |
E | SER889 | |
H | SER889 | |
Chain | Residue | Details |
B | TPO893 | |
E | TPO893 | |
H | TPO893 | |
G | LYS1121 | |