6SIV

Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008643	biological_process	carbohydrate transport
A	0015144	molecular_function	carbohydrate transmembrane transporter activity
A	0055085	biological_process	transmembrane transport
B	0003677	molecular_function	DNA binding
B	0005515	molecular_function	protein binding
B	0006351	biological_process	DNA-templated transcription
B	0006355	biological_process	regulation of DNA-templated transcription
B	0008270	molecular_function	zinc ion binding
B	0030162	biological_process	regulation of proteolysis
B	0030165	molecular_function	PDZ domain binding
B	0030430	cellular_component	host cell cytoplasm
B	0032489	biological_process	regulation of Cdc42 protein signal transduction
B	0033668	biological_process	symbiont-mediated suppression of host apoptosis
B	0039502	biological_process	symbiont-mediated suppression of host type I interferon-mediated signaling pathway
B	0039548	biological_process	symbiont-mediated suppression of host cytoplasmic pattern recognition receptor signaling pathway via inhibition of IRF3 activity
B	0039648	biological_process	symbiont-mediated perturbation of host ubiquitin-like protein modification
B	0039653	biological_process	symbiont-mediated suppression of host transcription
B	0042025	cellular_component	host cell nucleus
B	0042802	molecular_function	identical protein binding
B	0045944	biological_process	positive regulation of transcription by RNA polymerase II
B	0046872	molecular_function	metal ion binding
B	0052031	biological_process	symbiont-mediated perturbation of host defense response
B	0052150	biological_process	symbiont-mediated perturbation of host apoptosis
B	0052170	biological_process	symbiont-mediated suppression of host innate immune response
B	0060255	biological_process	regulation of macromolecule metabolic process
B	0080090	biological_process	regulation of primary metabolic process
B	0140537	molecular_function	transcription regulator activator activity

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
A	PRO108-ASN125

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	72
Details	Zinc finger: {"evidences":[{"source":"HAMAP-Rule","id":"MF_04006","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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