6SF2

Ternary complex of human bone morphogenetic protein 9 (BMP9) growth factor domain, its prodomain and extracellular domain of activin receptor-like kinase 1 (ALK1).

Functional Information from GO Data

Chain	GOid	namespace	contents
B	0005576	cellular_component	extracellular region
B	0008083	molecular_function	growth factor activity
C	0005576	cellular_component	extracellular region
E	0005576	cellular_component	extracellular region
E	0008083	molecular_function	growth factor activity
F	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00250
Number of Residues	16
Details	TGF_BETA_1 TGF-beta family signature. IiaPkeYeayeCkGgC

Chain	Residue	Details
B	ILE345-CYS360

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Region: {"description":"Mediates specificity for BMP ligand"}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	28
Details	Region: {"description":"Interaction with ENG","evidences":[{"source":"PubMed","id":"28564608","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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