Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| A | 0006633 | biological_process | fatty acid biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016746 | molecular_function | acyltransferase activity |
| B | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| B | 0006633 | biological_process | fatty acid biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016746 | molecular_function | acyltransferase activity |
| C | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| C | 0006633 | biological_process | fatty acid biosynthetic process |
| C | 0016740 | molecular_function | transferase activity |
| C | 0016746 | molecular_function | acyltransferase activity |
| D | 0004315 | molecular_function | 3-oxoacyl-[acyl-carrier-protein] synthase activity |
| D | 0006633 | biological_process | fatty acid biosynthetic process |
| D | 0016740 | molecular_function | transferase activity |
| D | 0016746 | molecular_function | acyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue OCA A 901 |
| Chain | Residue |
| A | SER112 |
| A | ALA160 |
| A | CYS161 |
| A | PHE200 |
| A | PHE395 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue CO8 D 903 |
| Chain | Residue |
| D | MET620 |
| D | ALA622 |
| D | GLY624 |
| D | ASN644 |
| D | ASP647 |
| D | THR648 |
| D | THR650 |
| D | PHE671 |
| D | LYS673 |
| D | LEU680 |
| D | LEU739 |
| D | LEU766 |
| D | VAL770 |
| D | ARG773 |
| D | OCA902 |
| D | MET499 |
| D | HIS580 |
| D | SER581 |
| D | LEU582 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for Di-peptide OCA B 901 and CYS B 161 |
| Chain | Residue |
| B | SER112 |
| B | THR159 |
| B | ALA160 |
| B | SER162 |
| B | SER163 |
| B | PHE200 |
| B | TYR222 |
| B | HIS331 |
| B | GLU333 |
| B | PRO334 |
| B | SER336 |
| B | SER392 |
| B | PHE393 |
| B | GLY394 |
| B | PHE395 |
| site_id | AC4 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide OCA C 901 and CYS C 161 |
| Chain | Residue |
| C | SER112 |
| C | THR159 |
| C | ALA160 |
| C | SER162 |
| C | SER163 |
| C | PHE200 |
| C | HIS331 |
| C | GLU333 |
| C | SER336 |
| C | SER392 |
| C | PHE393 |
| C | GLY394 |
| C | PHE395 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | binding site for Di-peptide OCA D 901 and CYS D 161 |
| Chain | Residue |
| D | THR159 |
| D | ALA160 |
| D | SER162 |
| D | SER163 |
| D | PHE200 |
| D | TYR222 |
| D | HIS331 |
| D | GLU333 |
| D | SER336 |
| D | SER392 |
| D | PHE393 |
| D | GLY394 |
| D | PHE395 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | binding site for Di-peptide OCA D 902 and SER D 581 |
| Chain | Residue |
| D | HIS580 |
| D | LEU582 |
| D | GLY583 |
| D | GLU584 |
| D | ARG606 |
| D | VAL639 |
| D | PRO640 |
| D | ALA641 |
| D | ASN738 |
| D | VAL740 |
| D | VAL743 |
| D | CO8903 |
Functional Information from PROSITE/UniProt
| site_id | PS00606 |
| Number of Residues | 17 |
| Details | KS3_1 Ketosynthase family 3 (KS3) active site signature. GPSiaLDtACSSSllAL |
| Chain | Residue | Details |
| A | GLY152-LEU168 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 776 |
| Details | Region: {"description":"Acyl and malonyl transferases"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Active site: {"description":"For beta-ketoacyl synthase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU01348","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"description":"For malonyltransferase activity","evidences":[{"source":"PROSITE-ProRule","id":"PRU10022","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31811668","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6ROP","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"23806337","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"UniProtKB","id":"P49327","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 14 |
| Details | Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"UniProtKB","id":"P49327","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]} |
