Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0000166 | molecular_function | nucleotide binding |
A | 0003824 | molecular_function | catalytic activity |
A | 0003938 | molecular_function | IMP dehydrogenase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006164 | biological_process | purine nucleotide biosynthetic process |
A | 0006177 | biological_process | GMP biosynthetic process |
A | 0006183 | biological_process | GTP biosynthetic process |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0020015 | cellular_component | glycosome |
A | 0046872 | molecular_function | metal ion binding |
B | 0000166 | molecular_function | nucleotide binding |
B | 0003824 | molecular_function | catalytic activity |
B | 0003938 | molecular_function | IMP dehydrogenase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006164 | biological_process | purine nucleotide biosynthetic process |
B | 0006177 | biological_process | GMP biosynthetic process |
B | 0006183 | biological_process | GTP biosynthetic process |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0020015 | cellular_component | glycosome |
B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 15 |
Details | binding site for residue ATP A 601 |
Chain | Residue |
A | SER136 |
A | HIS200 |
A | GLY201 |
A | TYR202 |
A | ARG219 |
B | LYS157 |
B | ARG199 |
A | CYS155 |
A | THR156 |
A | LYS157 |
A | ASP158 |
A | THR174 |
A | ASN178 |
A | MET179 |
A | THR180 |
site_id | AC2 |
Number of Residues | 10 |
Details | binding site for residue 5GP A 602 |
Chain | Residue |
A | LEU105 |
A | ILE111 |
A | MET112 |
A | LYS113 |
A | LYS115 |
A | LYS133 |
A | SER136 |
A | GLY137 |
A | TYR202 |
A | LEU215 |
site_id | AC3 |
Number of Residues | 13 |
Details | binding site for residue ATP B 601 |
Chain | Residue |
A | LYS157 |
A | ARG199 |
B | SER136 |
B | CYS155 |
B | THR156 |
B | ASP158 |
B | THR174 |
B | MET179 |
B | THR180 |
B | HIS200 |
B | GLY201 |
B | TYR202 |
B | ARG219 |
site_id | AC4 |
Number of Residues | 9 |
Details | binding site for residue 5GP B 602 |
Chain | Residue |
B | ILE111 |
B | LYS113 |
B | PRO114 |
B | LYS115 |
B | LYS133 |
B | ILE135 |
B | SER136 |
B | GLY137 |
B | LEU215 |
Functional Information from PROSITE/UniProt
site_id | PS00487 |
Number of Residues | 13 |
Details | IMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. LRIGMGsGSICiT |
Chain | Residue | Details |
A | LEU315-THR327 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | CYS325 | |
B | CYS325 | |
Chain | Residue | Details |
A | ARG423 | |
B | ARG423 | |
Chain | Residue | Details |
A | ASP268 | |
B | ASP268 | |
B | GLY318 | |
B | SER323 | |
B | ASP358 | |
B | GLY381 | |
B | TYR405 | |
B | GLN435 | |
B | GLU494 | |
B | GLY495 | |
A | GLY318 | |
A | SER323 | |
A | ASP358 | |
A | GLY381 | |
A | TYR405 | |
A | GLN435 | |
A | GLU494 | |
A | GLY495 | |
Chain | Residue | Details |
A | GLY320 | |
A | GLY322 | |
A | CYS325 | |
B | GLY320 | |
B | GLY322 | |
B | CYS325 | |