6R0Q

Mutant cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with thalidomide metabolite alpha-(o-carboxybenzamido)glutarimide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0046872	molecular_function	metal ion binding
B	0046872	molecular_function	metal ion binding
C	0046872	molecular_function	metal ion binding
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 201

Chain	Residue
A	CYS24
A	CYS27
A	CYS90
A	CYS93

---

site_id	AC2
Number of Residues	16
Details	binding site for residue JNW A 202

Chain	Residue
A	TRP79
A	TRP85
A	HIS96
A	TRP99
A	TYR101
A	HOH344
B	ASN68
B	GLY91
B	CYS93
B	GLY94
B	HOH326
A	ASN50
A	PRO51
A	HIS56
A	PHE77
A	SER78

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN B 201

Chain	Residue
B	CYS24
B	CYS27
B	CYS90
B	CYS93

---

site_id	AC4
Number of Residues	15
Details	binding site for residue JNW B 202

Chain	Residue
A	ASN68
A	GLY91
A	CYS93
A	GLY94
A	HOH324
B	ASN50
B	PRO51
B	HIS56
B	PHE77
B	SER78
B	TRP79
B	TRP85
B	TRP99
B	TYR101
B	HOH337

---

site_id	AC5
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	CYS24
C	CYS27
C	CYS90
C	CYS93

---

site_id	AC6
Number of Residues	16
Details	binding site for residue JNW C 202

Chain	Residue
C	ASN50
C	PRO51
C	HIS56
C	PHE77
C	SER78
C	TRP79
C	TRP85
C	HIS96
C	TRP99
C	TYR101
C	HOH354
D	ASN68
D	GLY91
D	CYS93
D	GLY94
D	HOH317

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN D 201

Chain	Residue
D	CYS24
D	CYS27
D	CYS90
D	CYS93

---

site_id	AC8
Number of Residues	16
Details	binding site for residue JNW D 202

Chain	Residue
C	ASN68
C	GLY91
C	CYS93
C	GLY94
C	HOH327
D	ASN50
D	PRO51
D	HIS56
D	PHE77
D	SER78
D	TRP79
D	TRP85
D	HIS96
D	TRP99
D	TYR101
D	HOH343

---