Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0043066 | biological_process | negative regulation of apoptotic process |
| A | 0051726 | biological_process | regulation of cell cycle |
| B | 0005634 | cellular_component | nucleus |
| B | 0043066 | biological_process | negative regulation of apoptotic process |
| B | 0051726 | biological_process | regulation of cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue HRT A 201 |
| Chain | Residue |
| A | MET54 |
| A | LEU99 |
| A | TYR100 |
| A | O4B204 |
| A | HOH302 |
| A | HOH305 |
| A | HOH325 |
| A | HOH326 |
| A | GLY58 |
| A | ILE61 |
| A | MET62 |
| A | TYR67 |
| A | GLN69 |
| A | GLN72 |
| A | MET74 |
| A | PRO96 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 202 |
| Chain | Residue |
| A | GLY45 |
| A | GLU46 |
| A | MET47 |
| A | HOH327 |
| B | ARG88 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue O4B A 203 |
| Chain | Residue |
| A | PRO33 |
| A | LYS36 |
| B | GLN65 |
| B | TYR76 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue O4B A 204 |
| Chain | Residue |
| A | VAL50 |
| A | LYS94 |
| A | TYR100 |
| A | THR109 |
| A | HRT201 |
| site_id | AC5 |
| Number of Residues | 10 |
| Details | binding site for residue HRT B 201 |
| Chain | Residue |
| B | LYS51 |
| B | MET54 |
| B | GLY58 |
| B | ILE61 |
| B | GLN69 |
| B | GLN72 |
| B | LEU99 |
| B | O4B204 |
| B | HOH310 |
| B | HOH332 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| A | ARG88 |
| B | GLY45 |
| B | GLU46 |
| B | MET47 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | binding site for residue O4B B 203 |
| Chain | Residue |
| A | GLN65 |
| A | TYR67 |
| A | TYR76 |
| B | LEU32 |
| B | LYS36 |
| B | GLN65 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue O4B B 204 |
| Chain | Residue |
| B | ASN26 |
| B | VAL50 |
| B | GLN72 |
| B | VAL93 |
| B | LYS94 |
| B | TYR100 |
| B | HRT201 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 166 |
| Details | Domain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]} |
