Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0004713 | molecular_function | protein tyrosine kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 14 |
| Details | binding site for residue ACP A 801 |
| Chain | Residue |
| A | LEU478 |
| A | ASN562 |
| A | LEU624 |
| A | HOH959 |
| A | HOH996 |
| A | HOH997 |
| A | GLU480 |
| A | GLY481 |
| A | PHE483 |
| A | ALA506 |
| A | VAL555 |
| A | GLU556 |
| A | TYR557 |
| A | ALA558 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 802 |
| Chain | Residue |
| A | ASP593 |
| A | CYS597 |
| A | ASN629 |
| site_id | AC3 |
| Number of Residues | 14 |
| Details | binding site for residue ACP B 801 |
| Chain | Residue |
| A | TYR647 |
| B | LEU478 |
| B | GLY479 |
| B | GLU480 |
| B | GLY481 |
| B | GLU556 |
| B | TYR557 |
| B | ALA558 |
| B | ASN622 |
| B | LEU624 |
| B | ASP635 |
| B | HOH904 |
| B | HOH962 |
| B | HOH978 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 802 |
| Chain | Residue |
| B | LYS560 |
| B | PHE566 |
| B | ARG570 |
| B | GLU586 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 31 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGQVVmAeaigidkdraakpvt...VAVK |
| Chain | Residue | Details |
| A | LEU478-LYS508 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. CIHrDLAARNVLV |
| Chain | Residue | Details |
| A | CYS613-VAL625 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"8754806","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"11294897","evidenceCode":"ECO:0000269"}]} |
