6P67

Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0004896	molecular_function	cytokine receptor activity
G	0016020	cellular_component	membrane
I	0004896	molecular_function	cytokine receptor activity
I	0016020	cellular_component	membrane
J	0004896	molecular_function	cytokine receptor activity
J	0016020	cellular_component	membrane
K	0004896	molecular_function	cytokine receptor activity
K	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
B	TYR192-HIS198
A	TYR201-HIS207

---

site_id	PS01355
Number of Residues	32
Details	HEMATOPO_REC_S_F1 Short hematopoietin receptor family 1 signature. LqpaamyeikVRsipdhyfkgf..........WSeWSpsyyF

Chain	Residue	Details
G	LEU175-PHE206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	400
Details	Domain: {"description":"Fibronectin type-III","evidences":[{"source":"PROSITE-ProRule","id":"PRU00316","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	16
Details	Motif: {"description":"WSXWS motif"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	12
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19141282","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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