6P67

Crystal Structure of a Complex of human IL-7Ralpha with an anti-IL-7Ralpha 2B8 Fab

Functional Information from GO Data

Chain	GOid	namespace	contents
G	0004896	molecular_function	cytokine receptor activity
G	0016020	cellular_component	membrane
I	0004896	molecular_function	cytokine receptor activity
I	0016020	cellular_component	membrane
J	0004896	molecular_function	cytokine receptor activity
J	0016020	cellular_component	membrane
K	0004896	molecular_function	cytokine receptor activity
K	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
B	TYR192-HIS198
A	TYR201-HIS207

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site_id	PS01355
Number of Residues	32
Details	HEMATOPO_REC_S_F1 Short hematopoietin receptor family 1 signature. LqpaamyeikVRsipdhyfkgf..........WSeWSpsyyF

Chain	Residue	Details
G	LEU175-PHE206

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	872
Details	TOPO_DOM: Extracellular => ECO:0000255

Chain	Residue	Details
G	GLU1-ASP219
I	GLU1-ASP219
J	GLU1-ASP219
K	GLU1-ASP219

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site_id	SWS_FT_FI2
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19141282

Chain	Residue	Details
G	ASN29
K	ASN29
K	ASN45
K	ASN131
G	ASN45
G	ASN131
I	ASN29
I	ASN45
I	ASN131
J	ASN29
J	ASN45
J	ASN131

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site_id	SWS_FT_FI3
Number of Residues	12
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
G	ASN162
K	ASN162
K	ASN212
K	ASN213
G	ASN212
G	ASN213
I	ASN162
I	ASN212
I	ASN213
J	ASN162
J	ASN212
J	ASN213

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