Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 22 |
| Details | binding site for residue Y35 A 301 |
| Chain | Residue |
| A | ASP218 |
| A | SO4302 |
| A | PGE303 |
| A | HOH433 |
| B | GLN117 |
| B | ASP218 |
| B | SER219 |
| B | CYS220 |
| B | SER224 |
| B | TRP244 |
| B | GLY245 |
| A | SER219 |
| B | GLU246 |
| B | GLY247 |
| B | PGE304 |
| A | GLN221 |
| A | SER224 |
| A | TRP244 |
| A | GLY245 |
| A | GLU246 |
| A | GLY247 |
| A | CYS248 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | HIS74 |
| A | GLN221 |
| A | GLY222 |
| A | SER224 |
| A | Y35301 |
| A | PGE303 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue PGE A 303 |
| Chain | Residue |
| A | HIS74 |
| A | PRO78 |
| A | PHE113 |
| A | TYR114 |
| A | ALA116 |
| A | SER243 |
| A | Y35301 |
| A | SO4302 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | HIS74 |
| B | GLN221 |
| B | GLY222 |
| B | SER224 |
| B | PGE304 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | ASN214 |
| B | THR215 |
| B | ARG216 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MES B 303 |
| Chain | Residue |
| A | LYS132 |
| A | SER134 |
| B | ARG203 |
| B | ARG206 |
| B | ASP207 |
| B | HOH455 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue PGE B 304 |
| Chain | Residue |
| A | Y35301 |
| B | HIS74 |
| B | PRO78 |
| B | TYR114 |
| B | ALA116 |
| B | SER243 |
| B | TRP244 |
| B | SO4301 |
| B | HOH428 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| A | LEU70-CYS75 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
| Chain | Residue | Details |
| A | ASP218-VAL229 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 482 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"}]} |
