Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004252 | molecular_function | serine-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 22 |
Details | binding site for residue Y35 A 301 |
Chain | Residue |
A | ASP218 |
A | SO4302 |
A | PGE303 |
A | HOH433 |
B | GLN117 |
B | ASP218 |
B | SER219 |
B | CYS220 |
B | SER224 |
B | TRP244 |
B | GLY245 |
A | SER219 |
B | GLU246 |
B | GLY247 |
B | PGE304 |
A | GLN221 |
A | SER224 |
A | TRP244 |
A | GLY245 |
A | GLU246 |
A | GLY247 |
A | CYS248 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 302 |
Chain | Residue |
A | HIS74 |
A | GLN221 |
A | GLY222 |
A | SER224 |
A | Y35301 |
A | PGE303 |
site_id | AC3 |
Number of Residues | 8 |
Details | binding site for residue PGE A 303 |
Chain | Residue |
A | HIS74 |
A | PRO78 |
A | PHE113 |
A | TYR114 |
A | ALA116 |
A | SER243 |
A | Y35301 |
A | SO4302 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue SO4 B 301 |
Chain | Residue |
B | HIS74 |
B | GLN221 |
B | GLY222 |
B | SER224 |
B | PGE304 |
site_id | AC5 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 302 |
Chain | Residue |
B | ASN214 |
B | THR215 |
B | ARG216 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue MES B 303 |
Chain | Residue |
A | LYS132 |
A | SER134 |
B | ARG203 |
B | ARG206 |
B | ASP207 |
B | HOH455 |
site_id | AC7 |
Number of Residues | 9 |
Details | binding site for residue PGE B 304 |
Chain | Residue |
A | Y35301 |
B | HIS74 |
B | PRO78 |
B | TYR114 |
B | ALA116 |
B | SER243 |
B | TRP244 |
B | SO4301 |
B | HOH428 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
Chain | Residue | Details |
A | LEU70-CYS75 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPLV |
Chain | Residue | Details |
A | ASP218-VAL229 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 6 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
A | HIS74 | |
A | ASP121 | |
A | SER224 | |
B | HIS74 | |
B | ASP121 | |
B | SER224 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | LYS132 | |
B | LYS132 | |
Chain | Residue | Details |
A | ASN233 | |
B | ASN233 | |