6OIF

Cryo-EM structure of human TorsinA filament

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000338	biological_process	protein deneddylation
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005635	cellular_component	nuclear envelope
A	0005737	cellular_component	cytoplasm
A	0005783	cellular_component	endoplasmic reticulum
A	0005788	cellular_component	endoplasmic reticulum lumen
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005829	cellular_component	cytosol
A	0005856	cellular_component	cytoskeleton
A	0006979	biological_process	response to oxidative stress
A	0006996	biological_process	organelle organization
A	0006998	biological_process	nuclear envelope organization
A	0007155	biological_process	cell adhesion
A	0008021	cellular_component	synaptic vesicle
A	0008092	molecular_function	cytoskeletal protein binding
A	0012505	cellular_component	endomembrane system
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0019894	molecular_function	kinesin binding
A	0030141	cellular_component	secretory granule
A	0030426	cellular_component	growth cone
A	0030659	cellular_component	cytoplasmic vesicle membrane
A	0031175	biological_process	neuron projection development
A	0031410	cellular_component	cytoplasmic vesicle
A	0031965	cellular_component	nuclear membrane
A	0034504	biological_process	protein localization to nucleus
A	0036503	biological_process	ERAD pathway
A	0042802	molecular_function	identical protein binding
A	0042995	cellular_component	cell projection
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0044319	biological_process	wound healing, spreading of cells
A	0045104	biological_process	intermediate filament cytoskeleton organization
A	0045202	cellular_component	synapse
A	0048489	biological_process	synaptic vesicle transport
A	0048499	biological_process	synaptic vesicle membrane organization
A	0051082	molecular_function	unfolded protein binding
A	0051085	biological_process	chaperone cofactor-dependent protein refolding
A	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
A	0051787	molecular_function	misfolded protein binding
A	0061077	biological_process	chaperone-mediated protein folding
A	0070062	cellular_component	extracellular exosome
A	0071763	biological_process	nuclear membrane organization
A	0140662	molecular_function	ATP-dependent protein folding chaperone
A	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
A	2000008	biological_process	regulation of protein localization to cell surface
B	0000338	biological_process	protein deneddylation
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005634	cellular_component	nucleus
B	0005635	cellular_component	nuclear envelope
B	0005737	cellular_component	cytoplasm
B	0005783	cellular_component	endoplasmic reticulum
B	0005788	cellular_component	endoplasmic reticulum lumen
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005829	cellular_component	cytosol
B	0005856	cellular_component	cytoskeleton
B	0006979	biological_process	response to oxidative stress
B	0006996	biological_process	organelle organization
B	0006998	biological_process	nuclear envelope organization
B	0007155	biological_process	cell adhesion
B	0008021	cellular_component	synaptic vesicle
B	0008092	molecular_function	cytoskeletal protein binding
B	0012505	cellular_component	endomembrane system
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016887	molecular_function	ATP hydrolysis activity
B	0019894	molecular_function	kinesin binding
B	0030141	cellular_component	secretory granule
B	0030426	cellular_component	growth cone
B	0030659	cellular_component	cytoplasmic vesicle membrane
B	0031175	biological_process	neuron projection development
B	0031410	cellular_component	cytoplasmic vesicle
B	0031965	cellular_component	nuclear membrane
B	0034504	biological_process	protein localization to nucleus
B	0036503	biological_process	ERAD pathway
B	0042802	molecular_function	identical protein binding
B	0042995	cellular_component	cell projection
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0044319	biological_process	wound healing, spreading of cells
B	0045104	biological_process	intermediate filament cytoskeleton organization
B	0045202	cellular_component	synapse
B	0048489	biological_process	synaptic vesicle transport
B	0048499	biological_process	synaptic vesicle membrane organization
B	0051082	molecular_function	unfolded protein binding
B	0051085	biological_process	chaperone cofactor-dependent protein refolding
B	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
B	0051787	molecular_function	misfolded protein binding
B	0061077	biological_process	chaperone-mediated protein folding
B	0070062	cellular_component	extracellular exosome
B	0071763	biological_process	nuclear membrane organization
B	0140662	molecular_function	ATP-dependent protein folding chaperone
B	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
B	2000008	biological_process	regulation of protein localization to cell surface
C	0000338	biological_process	protein deneddylation
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005634	cellular_component	nucleus
C	0005635	cellular_component	nuclear envelope
C	0005737	cellular_component	cytoplasm
C	0005783	cellular_component	endoplasmic reticulum
C	0005788	cellular_component	endoplasmic reticulum lumen
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005829	cellular_component	cytosol
C	0005856	cellular_component	cytoskeleton
C	0006979	biological_process	response to oxidative stress
C	0006996	biological_process	organelle organization
C	0006998	biological_process	nuclear envelope organization
C	0007155	biological_process	cell adhesion
C	0008021	cellular_component	synaptic vesicle
C	0008092	molecular_function	cytoskeletal protein binding
C	0012505	cellular_component	endomembrane system
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0016887	molecular_function	ATP hydrolysis activity
C	0019894	molecular_function	kinesin binding
C	0030141	cellular_component	secretory granule
C	0030426	cellular_component	growth cone
C	0030659	cellular_component	cytoplasmic vesicle membrane
C	0031175	biological_process	neuron projection development
C	0031410	cellular_component	cytoplasmic vesicle
C	0031965	cellular_component	nuclear membrane
C	0034504	biological_process	protein localization to nucleus
C	0036503	biological_process	ERAD pathway
C	0042802	molecular_function	identical protein binding
C	0042995	cellular_component	cell projection
C	0043231	cellular_component	intracellular membrane-bounded organelle
C	0044319	biological_process	wound healing, spreading of cells
C	0045104	biological_process	intermediate filament cytoskeleton organization
C	0045202	cellular_component	synapse
C	0048489	biological_process	synaptic vesicle transport
C	0048499	biological_process	synaptic vesicle membrane organization
C	0051082	molecular_function	unfolded protein binding
C	0051085	biological_process	chaperone cofactor-dependent protein refolding
C	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
C	0051787	molecular_function	misfolded protein binding
C	0061077	biological_process	chaperone-mediated protein folding
C	0070062	cellular_component	extracellular exosome
C	0071763	biological_process	nuclear membrane organization
C	0140662	molecular_function	ATP-dependent protein folding chaperone
C	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
C	2000008	biological_process	regulation of protein localization to cell surface
D	0000338	biological_process	protein deneddylation
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005634	cellular_component	nucleus
D	0005635	cellular_component	nuclear envelope
D	0005737	cellular_component	cytoplasm
D	0005783	cellular_component	endoplasmic reticulum
D	0005788	cellular_component	endoplasmic reticulum lumen
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005829	cellular_component	cytosol
D	0005856	cellular_component	cytoskeleton
D	0006979	biological_process	response to oxidative stress
D	0006996	biological_process	organelle organization
D	0006998	biological_process	nuclear envelope organization
D	0007155	biological_process	cell adhesion
D	0008021	cellular_component	synaptic vesicle
D	0008092	molecular_function	cytoskeletal protein binding
D	0012505	cellular_component	endomembrane system
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016887	molecular_function	ATP hydrolysis activity
D	0019894	molecular_function	kinesin binding
D	0030141	cellular_component	secretory granule
D	0030426	cellular_component	growth cone
D	0030659	cellular_component	cytoplasmic vesicle membrane
D	0031175	biological_process	neuron projection development
D	0031410	cellular_component	cytoplasmic vesicle
D	0031965	cellular_component	nuclear membrane
D	0034504	biological_process	protein localization to nucleus
D	0036503	biological_process	ERAD pathway
D	0042802	molecular_function	identical protein binding
D	0042995	cellular_component	cell projection
D	0043231	cellular_component	intracellular membrane-bounded organelle
D	0044319	biological_process	wound healing, spreading of cells
D	0045104	biological_process	intermediate filament cytoskeleton organization
D	0045202	cellular_component	synapse
D	0048489	biological_process	synaptic vesicle transport
D	0048499	biological_process	synaptic vesicle membrane organization
D	0051082	molecular_function	unfolded protein binding
D	0051085	biological_process	chaperone cofactor-dependent protein refolding
D	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
D	0051787	molecular_function	misfolded protein binding
D	0061077	biological_process	chaperone-mediated protein folding
D	0070062	cellular_component	extracellular exosome
D	0071763	biological_process	nuclear membrane organization
D	0140662	molecular_function	ATP-dependent protein folding chaperone
D	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
D	2000008	biological_process	regulation of protein localization to cell surface
E	0000338	biological_process	protein deneddylation
E	0005515	molecular_function	protein binding
E	0005524	molecular_function	ATP binding
E	0005634	cellular_component	nucleus
E	0005635	cellular_component	nuclear envelope
E	0005737	cellular_component	cytoplasm
E	0005783	cellular_component	endoplasmic reticulum
E	0005788	cellular_component	endoplasmic reticulum lumen
E	0005789	cellular_component	endoplasmic reticulum membrane
E	0005829	cellular_component	cytosol
E	0005856	cellular_component	cytoskeleton
E	0006979	biological_process	response to oxidative stress
E	0006996	biological_process	organelle organization
E	0006998	biological_process	nuclear envelope organization
E	0007155	biological_process	cell adhesion
E	0008021	cellular_component	synaptic vesicle
E	0008092	molecular_function	cytoskeletal protein binding
E	0012505	cellular_component	endomembrane system
E	0016020	cellular_component	membrane
E	0016787	molecular_function	hydrolase activity
E	0016887	molecular_function	ATP hydrolysis activity
E	0019894	molecular_function	kinesin binding
E	0030141	cellular_component	secretory granule
E	0030426	cellular_component	growth cone
E	0030659	cellular_component	cytoplasmic vesicle membrane
E	0031175	biological_process	neuron projection development
E	0031410	cellular_component	cytoplasmic vesicle
E	0031965	cellular_component	nuclear membrane
E	0034504	biological_process	protein localization to nucleus
E	0036503	biological_process	ERAD pathway
E	0042802	molecular_function	identical protein binding
E	0042995	cellular_component	cell projection
E	0043231	cellular_component	intracellular membrane-bounded organelle
E	0044319	biological_process	wound healing, spreading of cells
E	0045104	biological_process	intermediate filament cytoskeleton organization
E	0045202	cellular_component	synapse
E	0048489	biological_process	synaptic vesicle transport
E	0048499	biological_process	synaptic vesicle membrane organization
E	0051082	molecular_function	unfolded protein binding
E	0051085	biological_process	chaperone cofactor-dependent protein refolding
E	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
E	0051787	molecular_function	misfolded protein binding
E	0061077	biological_process	chaperone-mediated protein folding
E	0070062	cellular_component	extracellular exosome
E	0071763	biological_process	nuclear membrane organization
E	0140662	molecular_function	ATP-dependent protein folding chaperone
E	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
E	2000008	biological_process	regulation of protein localization to cell surface
F	0000338	biological_process	protein deneddylation
F	0005515	molecular_function	protein binding
F	0005524	molecular_function	ATP binding
F	0005634	cellular_component	nucleus
F	0005635	cellular_component	nuclear envelope
F	0005737	cellular_component	cytoplasm
F	0005783	cellular_component	endoplasmic reticulum
F	0005788	cellular_component	endoplasmic reticulum lumen
F	0005789	cellular_component	endoplasmic reticulum membrane
F	0005829	cellular_component	cytosol
F	0005856	cellular_component	cytoskeleton
F	0006979	biological_process	response to oxidative stress
F	0006996	biological_process	organelle organization
F	0006998	biological_process	nuclear envelope organization
F	0007155	biological_process	cell adhesion
F	0008021	cellular_component	synaptic vesicle
F	0008092	molecular_function	cytoskeletal protein binding
F	0012505	cellular_component	endomembrane system
F	0016020	cellular_component	membrane
F	0016787	molecular_function	hydrolase activity
F	0016887	molecular_function	ATP hydrolysis activity
F	0019894	molecular_function	kinesin binding
F	0030141	cellular_component	secretory granule
F	0030426	cellular_component	growth cone
F	0030659	cellular_component	cytoplasmic vesicle membrane
F	0031175	biological_process	neuron projection development
F	0031410	cellular_component	cytoplasmic vesicle
F	0031965	cellular_component	nuclear membrane
F	0034504	biological_process	protein localization to nucleus
F	0036503	biological_process	ERAD pathway
F	0042802	molecular_function	identical protein binding
F	0042995	cellular_component	cell projection
F	0043231	cellular_component	intracellular membrane-bounded organelle
F	0044319	biological_process	wound healing, spreading of cells
F	0045104	biological_process	intermediate filament cytoskeleton organization
F	0045202	cellular_component	synapse
F	0048489	biological_process	synaptic vesicle transport
F	0048499	biological_process	synaptic vesicle membrane organization
F	0051082	molecular_function	unfolded protein binding
F	0051085	biological_process	chaperone cofactor-dependent protein refolding
F	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
F	0051787	molecular_function	misfolded protein binding
F	0061077	biological_process	chaperone-mediated protein folding
F	0070062	cellular_component	extracellular exosome
F	0071763	biological_process	nuclear membrane organization
F	0140662	molecular_function	ATP-dependent protein folding chaperone
F	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
F	2000008	biological_process	regulation of protein localization to cell surface
G	0000338	biological_process	protein deneddylation
G	0005515	molecular_function	protein binding
G	0005524	molecular_function	ATP binding
G	0005634	cellular_component	nucleus
G	0005635	cellular_component	nuclear envelope
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0005788	cellular_component	endoplasmic reticulum lumen
G	0005789	cellular_component	endoplasmic reticulum membrane
G	0005829	cellular_component	cytosol
G	0005856	cellular_component	cytoskeleton
G	0006979	biological_process	response to oxidative stress
G	0006996	biological_process	organelle organization
G	0006998	biological_process	nuclear envelope organization
G	0007155	biological_process	cell adhesion
G	0008021	cellular_component	synaptic vesicle
G	0008092	molecular_function	cytoskeletal protein binding
G	0012505	cellular_component	endomembrane system
G	0016020	cellular_component	membrane
G	0016787	molecular_function	hydrolase activity
G	0016887	molecular_function	ATP hydrolysis activity
G	0019894	molecular_function	kinesin binding
G	0030141	cellular_component	secretory granule
G	0030426	cellular_component	growth cone
G	0030659	cellular_component	cytoplasmic vesicle membrane
G	0031175	biological_process	neuron projection development
G	0031410	cellular_component	cytoplasmic vesicle
G	0031965	cellular_component	nuclear membrane
G	0034504	biological_process	protein localization to nucleus
G	0036503	biological_process	ERAD pathway
G	0042802	molecular_function	identical protein binding
G	0042995	cellular_component	cell projection
G	0043231	cellular_component	intracellular membrane-bounded organelle
G	0044319	biological_process	wound healing, spreading of cells
G	0045104	biological_process	intermediate filament cytoskeleton organization
G	0045202	cellular_component	synapse
G	0048489	biological_process	synaptic vesicle transport
G	0048499	biological_process	synaptic vesicle membrane organization
G	0051082	molecular_function	unfolded protein binding
G	0051085	biological_process	chaperone cofactor-dependent protein refolding
G	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
G	0051787	molecular_function	misfolded protein binding
G	0061077	biological_process	chaperone-mediated protein folding
G	0070062	cellular_component	extracellular exosome
G	0071763	biological_process	nuclear membrane organization
G	0140662	molecular_function	ATP-dependent protein folding chaperone
G	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
G	2000008	biological_process	regulation of protein localization to cell surface
H	0000338	biological_process	protein deneddylation
H	0005515	molecular_function	protein binding
H	0005524	molecular_function	ATP binding
H	0005634	cellular_component	nucleus
H	0005635	cellular_component	nuclear envelope
H	0005737	cellular_component	cytoplasm
H	0005783	cellular_component	endoplasmic reticulum
H	0005788	cellular_component	endoplasmic reticulum lumen
H	0005789	cellular_component	endoplasmic reticulum membrane
H	0005829	cellular_component	cytosol
H	0005856	cellular_component	cytoskeleton
H	0006979	biological_process	response to oxidative stress
H	0006996	biological_process	organelle organization
H	0006998	biological_process	nuclear envelope organization
H	0007155	biological_process	cell adhesion
H	0008021	cellular_component	synaptic vesicle
H	0008092	molecular_function	cytoskeletal protein binding
H	0012505	cellular_component	endomembrane system
H	0016020	cellular_component	membrane
H	0016787	molecular_function	hydrolase activity
H	0016887	molecular_function	ATP hydrolysis activity
H	0019894	molecular_function	kinesin binding
H	0030141	cellular_component	secretory granule
H	0030426	cellular_component	growth cone
H	0030659	cellular_component	cytoplasmic vesicle membrane
H	0031175	biological_process	neuron projection development
H	0031410	cellular_component	cytoplasmic vesicle
H	0031965	cellular_component	nuclear membrane
H	0034504	biological_process	protein localization to nucleus
H	0036503	biological_process	ERAD pathway
H	0042802	molecular_function	identical protein binding
H	0042995	cellular_component	cell projection
H	0043231	cellular_component	intracellular membrane-bounded organelle
H	0044319	biological_process	wound healing, spreading of cells
H	0045104	biological_process	intermediate filament cytoskeleton organization
H	0045202	cellular_component	synapse
H	0048489	biological_process	synaptic vesicle transport
H	0048499	biological_process	synaptic vesicle membrane organization
H	0051082	molecular_function	unfolded protein binding
H	0051085	biological_process	chaperone cofactor-dependent protein refolding
H	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
H	0051787	molecular_function	misfolded protein binding
H	0061077	biological_process	chaperone-mediated protein folding
H	0070062	cellular_component	extracellular exosome
H	0071763	biological_process	nuclear membrane organization
H	0140662	molecular_function	ATP-dependent protein folding chaperone
H	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
H	2000008	biological_process	regulation of protein localization to cell surface
I	0000338	biological_process	protein deneddylation
I	0005515	molecular_function	protein binding
I	0005524	molecular_function	ATP binding
I	0005634	cellular_component	nucleus
I	0005635	cellular_component	nuclear envelope
I	0005737	cellular_component	cytoplasm
I	0005783	cellular_component	endoplasmic reticulum
I	0005788	cellular_component	endoplasmic reticulum lumen
I	0005789	cellular_component	endoplasmic reticulum membrane
I	0005829	cellular_component	cytosol
I	0005856	cellular_component	cytoskeleton
I	0006979	biological_process	response to oxidative stress
I	0006996	biological_process	organelle organization
I	0006998	biological_process	nuclear envelope organization
I	0007155	biological_process	cell adhesion
I	0008021	cellular_component	synaptic vesicle
I	0008092	molecular_function	cytoskeletal protein binding
I	0012505	cellular_component	endomembrane system
I	0016020	cellular_component	membrane
I	0016787	molecular_function	hydrolase activity
I	0016887	molecular_function	ATP hydrolysis activity
I	0019894	molecular_function	kinesin binding
I	0030141	cellular_component	secretory granule
I	0030426	cellular_component	growth cone
I	0030659	cellular_component	cytoplasmic vesicle membrane
I	0031175	biological_process	neuron projection development
I	0031410	cellular_component	cytoplasmic vesicle
I	0031965	cellular_component	nuclear membrane
I	0034504	biological_process	protein localization to nucleus
I	0036503	biological_process	ERAD pathway
I	0042802	molecular_function	identical protein binding
I	0042995	cellular_component	cell projection
I	0043231	cellular_component	intracellular membrane-bounded organelle
I	0044319	biological_process	wound healing, spreading of cells
I	0045104	biological_process	intermediate filament cytoskeleton organization
I	0045202	cellular_component	synapse
I	0048489	biological_process	synaptic vesicle transport
I	0048499	biological_process	synaptic vesicle membrane organization
I	0051082	molecular_function	unfolded protein binding
I	0051085	biological_process	chaperone cofactor-dependent protein refolding
I	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
I	0051787	molecular_function	misfolded protein binding
I	0061077	biological_process	chaperone-mediated protein folding
I	0070062	cellular_component	extracellular exosome
I	0071763	biological_process	nuclear membrane organization
I	0140662	molecular_function	ATP-dependent protein folding chaperone
I	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
I	2000008	biological_process	regulation of protein localization to cell surface
J	0000338	biological_process	protein deneddylation
J	0005515	molecular_function	protein binding
J	0005524	molecular_function	ATP binding
J	0005634	cellular_component	nucleus
J	0005635	cellular_component	nuclear envelope
J	0005737	cellular_component	cytoplasm
J	0005783	cellular_component	endoplasmic reticulum
J	0005788	cellular_component	endoplasmic reticulum lumen
J	0005789	cellular_component	endoplasmic reticulum membrane
J	0005829	cellular_component	cytosol
J	0005856	cellular_component	cytoskeleton
J	0006979	biological_process	response to oxidative stress
J	0006996	biological_process	organelle organization
J	0006998	biological_process	nuclear envelope organization
J	0007155	biological_process	cell adhesion
J	0008021	cellular_component	synaptic vesicle
J	0008092	molecular_function	cytoskeletal protein binding
J	0012505	cellular_component	endomembrane system
J	0016020	cellular_component	membrane
J	0016787	molecular_function	hydrolase activity
J	0016887	molecular_function	ATP hydrolysis activity
J	0019894	molecular_function	kinesin binding
J	0030141	cellular_component	secretory granule
J	0030426	cellular_component	growth cone
J	0030659	cellular_component	cytoplasmic vesicle membrane
J	0031175	biological_process	neuron projection development
J	0031410	cellular_component	cytoplasmic vesicle
J	0031965	cellular_component	nuclear membrane
J	0034504	biological_process	protein localization to nucleus
J	0036503	biological_process	ERAD pathway
J	0042802	molecular_function	identical protein binding
J	0042995	cellular_component	cell projection
J	0043231	cellular_component	intracellular membrane-bounded organelle
J	0044319	biological_process	wound healing, spreading of cells
J	0045104	biological_process	intermediate filament cytoskeleton organization
J	0045202	cellular_component	synapse
J	0048489	biological_process	synaptic vesicle transport
J	0048499	biological_process	synaptic vesicle membrane organization
J	0051082	molecular_function	unfolded protein binding
J	0051085	biological_process	chaperone cofactor-dependent protein refolding
J	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
J	0051787	molecular_function	misfolded protein binding
J	0061077	biological_process	chaperone-mediated protein folding
J	0070062	cellular_component	extracellular exosome
J	0071763	biological_process	nuclear membrane organization
J	0140662	molecular_function	ATP-dependent protein folding chaperone
J	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
J	2000008	biological_process	regulation of protein localization to cell surface
K	0000338	biological_process	protein deneddylation
K	0005515	molecular_function	protein binding
K	0005524	molecular_function	ATP binding
K	0005634	cellular_component	nucleus
K	0005635	cellular_component	nuclear envelope
K	0005737	cellular_component	cytoplasm
K	0005783	cellular_component	endoplasmic reticulum
K	0005788	cellular_component	endoplasmic reticulum lumen
K	0005789	cellular_component	endoplasmic reticulum membrane
K	0005829	cellular_component	cytosol
K	0005856	cellular_component	cytoskeleton
K	0006979	biological_process	response to oxidative stress
K	0006996	biological_process	organelle organization
K	0006998	biological_process	nuclear envelope organization
K	0007155	biological_process	cell adhesion
K	0008021	cellular_component	synaptic vesicle
K	0008092	molecular_function	cytoskeletal protein binding
K	0012505	cellular_component	endomembrane system
K	0016020	cellular_component	membrane
K	0016787	molecular_function	hydrolase activity
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K	0036503	biological_process	ERAD pathway
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K	0042995	cellular_component	cell projection
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M	0005788	cellular_component	endoplasmic reticulum lumen
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M	0005856	cellular_component	cytoskeleton
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M	0006998	biological_process	nuclear envelope organization
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M	0012505	cellular_component	endomembrane system
M	0016020	cellular_component	membrane
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M	0030659	cellular_component	cytoplasmic vesicle membrane
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M	0051085	biological_process	chaperone cofactor-dependent protein refolding
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M	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
M	2000008	biological_process	regulation of protein localization to cell surface
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Q	0005737	cellular_component	cytoplasm
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Q	0005788	cellular_component	endoplasmic reticulum lumen
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Q	0012505	cellular_component	endomembrane system
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Q	0030659	cellular_component	cytoplasmic vesicle membrane
Q	0031175	biological_process	neuron projection development
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R	0005788	cellular_component	endoplasmic reticulum lumen
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R	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
R	2000008	biological_process	regulation of protein localization to cell surface
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S	0005635	cellular_component	nuclear envelope
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S	0005783	cellular_component	endoplasmic reticulum
S	0005788	cellular_component	endoplasmic reticulum lumen
S	0005789	cellular_component	endoplasmic reticulum membrane
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S	0030426	cellular_component	growth cone
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S	0036503	biological_process	ERAD pathway
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S	2000008	biological_process	regulation of protein localization to cell surface
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T	0005635	cellular_component	nuclear envelope
T	0005737	cellular_component	cytoplasm
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T	0005788	cellular_component	endoplasmic reticulum lumen
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U	0048499	biological_process	synaptic vesicle membrane organization
U	0051082	molecular_function	unfolded protein binding
U	0051085	biological_process	chaperone cofactor-dependent protein refolding
U	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
U	0051787	molecular_function	misfolded protein binding
U	0061077	biological_process	chaperone-mediated protein folding
U	0070062	cellular_component	extracellular exosome
U	0071763	biological_process	nuclear membrane organization
U	0140662	molecular_function	ATP-dependent protein folding chaperone
U	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
U	2000008	biological_process	regulation of protein localization to cell surface
V	0000338	biological_process	protein deneddylation
V	0005515	molecular_function	protein binding
V	0005524	molecular_function	ATP binding
V	0005634	cellular_component	nucleus
V	0005635	cellular_component	nuclear envelope
V	0005737	cellular_component	cytoplasm
V	0005783	cellular_component	endoplasmic reticulum
V	0005788	cellular_component	endoplasmic reticulum lumen
V	0005789	cellular_component	endoplasmic reticulum membrane
V	0005829	cellular_component	cytosol
V	0005856	cellular_component	cytoskeleton
V	0006979	biological_process	response to oxidative stress
V	0006996	biological_process	organelle organization
V	0006998	biological_process	nuclear envelope organization
V	0007155	biological_process	cell adhesion
V	0008021	cellular_component	synaptic vesicle
V	0008092	molecular_function	cytoskeletal protein binding
V	0012505	cellular_component	endomembrane system
V	0016020	cellular_component	membrane
V	0016787	molecular_function	hydrolase activity
V	0016887	molecular_function	ATP hydrolysis activity
V	0019894	molecular_function	kinesin binding
V	0030141	cellular_component	secretory granule
V	0030426	cellular_component	growth cone
V	0030659	cellular_component	cytoplasmic vesicle membrane
V	0031175	biological_process	neuron projection development
V	0031410	cellular_component	cytoplasmic vesicle
V	0031965	cellular_component	nuclear membrane
V	0034504	biological_process	protein localization to nucleus
V	0036503	biological_process	ERAD pathway
V	0042802	molecular_function	identical protein binding
V	0042995	cellular_component	cell projection
V	0043231	cellular_component	intracellular membrane-bounded organelle
V	0044319	biological_process	wound healing, spreading of cells
V	0045104	biological_process	intermediate filament cytoskeleton organization
V	0045202	cellular_component	synapse
V	0048489	biological_process	synaptic vesicle transport
V	0048499	biological_process	synaptic vesicle membrane organization
V	0051082	molecular_function	unfolded protein binding
V	0051085	biological_process	chaperone cofactor-dependent protein refolding
V	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
V	0051787	molecular_function	misfolded protein binding
V	0061077	biological_process	chaperone-mediated protein folding
V	0070062	cellular_component	extracellular exosome
V	0071763	biological_process	nuclear membrane organization
V	0140662	molecular_function	ATP-dependent protein folding chaperone
V	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
V	2000008	biological_process	regulation of protein localization to cell surface
W	0000338	biological_process	protein deneddylation
W	0005515	molecular_function	protein binding
W	0005524	molecular_function	ATP binding
W	0005634	cellular_component	nucleus
W	0005635	cellular_component	nuclear envelope
W	0005737	cellular_component	cytoplasm
W	0005783	cellular_component	endoplasmic reticulum
W	0005788	cellular_component	endoplasmic reticulum lumen
W	0005789	cellular_component	endoplasmic reticulum membrane
W	0005829	cellular_component	cytosol
W	0005856	cellular_component	cytoskeleton
W	0006979	biological_process	response to oxidative stress
W	0006996	biological_process	organelle organization
W	0006998	biological_process	nuclear envelope organization
W	0007155	biological_process	cell adhesion
W	0008021	cellular_component	synaptic vesicle
W	0008092	molecular_function	cytoskeletal protein binding
W	0012505	cellular_component	endomembrane system
W	0016020	cellular_component	membrane
W	0016787	molecular_function	hydrolase activity
W	0016887	molecular_function	ATP hydrolysis activity
W	0019894	molecular_function	kinesin binding
W	0030141	cellular_component	secretory granule
W	0030426	cellular_component	growth cone
W	0030659	cellular_component	cytoplasmic vesicle membrane
W	0031175	biological_process	neuron projection development
W	0031410	cellular_component	cytoplasmic vesicle
W	0031965	cellular_component	nuclear membrane
W	0034504	biological_process	protein localization to nucleus
W	0036503	biological_process	ERAD pathway
W	0042802	molecular_function	identical protein binding
W	0042995	cellular_component	cell projection
W	0043231	cellular_component	intracellular membrane-bounded organelle
W	0044319	biological_process	wound healing, spreading of cells
W	0045104	biological_process	intermediate filament cytoskeleton organization
W	0045202	cellular_component	synapse
W	0048489	biological_process	synaptic vesicle transport
W	0048499	biological_process	synaptic vesicle membrane organization
W	0051082	molecular_function	unfolded protein binding
W	0051085	biological_process	chaperone cofactor-dependent protein refolding
W	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
W	0051787	molecular_function	misfolded protein binding
W	0061077	biological_process	chaperone-mediated protein folding
W	0070062	cellular_component	extracellular exosome
W	0071763	biological_process	nuclear membrane organization
W	0140662	molecular_function	ATP-dependent protein folding chaperone
W	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
W	2000008	biological_process	regulation of protein localization to cell surface
X	0000338	biological_process	protein deneddylation
X	0005515	molecular_function	protein binding
X	0005524	molecular_function	ATP binding
X	0005634	cellular_component	nucleus
X	0005635	cellular_component	nuclear envelope
X	0005737	cellular_component	cytoplasm
X	0005783	cellular_component	endoplasmic reticulum
X	0005788	cellular_component	endoplasmic reticulum lumen
X	0005789	cellular_component	endoplasmic reticulum membrane
X	0005829	cellular_component	cytosol
X	0005856	cellular_component	cytoskeleton
X	0006979	biological_process	response to oxidative stress
X	0006996	biological_process	organelle organization
X	0006998	biological_process	nuclear envelope organization
X	0007155	biological_process	cell adhesion
X	0008021	cellular_component	synaptic vesicle
X	0008092	molecular_function	cytoskeletal protein binding
X	0012505	cellular_component	endomembrane system
X	0016020	cellular_component	membrane
X	0016787	molecular_function	hydrolase activity
X	0016887	molecular_function	ATP hydrolysis activity
X	0019894	molecular_function	kinesin binding
X	0030141	cellular_component	secretory granule
X	0030426	cellular_component	growth cone
X	0030659	cellular_component	cytoplasmic vesicle membrane
X	0031175	biological_process	neuron projection development
X	0031410	cellular_component	cytoplasmic vesicle
X	0031965	cellular_component	nuclear membrane
X	0034504	biological_process	protein localization to nucleus
X	0036503	biological_process	ERAD pathway
X	0042802	molecular_function	identical protein binding
X	0042995	cellular_component	cell projection
X	0043231	cellular_component	intracellular membrane-bounded organelle
X	0044319	biological_process	wound healing, spreading of cells
X	0045104	biological_process	intermediate filament cytoskeleton organization
X	0045202	cellular_component	synapse
X	0048489	biological_process	synaptic vesicle transport
X	0048499	biological_process	synaptic vesicle membrane organization
X	0051082	molecular_function	unfolded protein binding
X	0051085	biological_process	chaperone cofactor-dependent protein refolding
X	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
X	0051787	molecular_function	misfolded protein binding
X	0061077	biological_process	chaperone-mediated protein folding
X	0070062	cellular_component	extracellular exosome
X	0071763	biological_process	nuclear membrane organization
X	0140662	molecular_function	ATP-dependent protein folding chaperone
X	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
X	2000008	biological_process	regulation of protein localization to cell surface
Y	0000338	biological_process	protein deneddylation
Y	0005515	molecular_function	protein binding
Y	0005524	molecular_function	ATP binding
Y	0005634	cellular_component	nucleus
Y	0005635	cellular_component	nuclear envelope
Y	0005737	cellular_component	cytoplasm
Y	0005783	cellular_component	endoplasmic reticulum
Y	0005788	cellular_component	endoplasmic reticulum lumen
Y	0005789	cellular_component	endoplasmic reticulum membrane
Y	0005829	cellular_component	cytosol
Y	0005856	cellular_component	cytoskeleton
Y	0006979	biological_process	response to oxidative stress
Y	0006996	biological_process	organelle organization
Y	0006998	biological_process	nuclear envelope organization
Y	0007155	biological_process	cell adhesion
Y	0008021	cellular_component	synaptic vesicle
Y	0008092	molecular_function	cytoskeletal protein binding
Y	0012505	cellular_component	endomembrane system
Y	0016020	cellular_component	membrane
Y	0016787	molecular_function	hydrolase activity
Y	0016887	molecular_function	ATP hydrolysis activity
Y	0019894	molecular_function	kinesin binding
Y	0030141	cellular_component	secretory granule
Y	0030426	cellular_component	growth cone
Y	0030659	cellular_component	cytoplasmic vesicle membrane
Y	0031175	biological_process	neuron projection development
Y	0031410	cellular_component	cytoplasmic vesicle
Y	0031965	cellular_component	nuclear membrane
Y	0034504	biological_process	protein localization to nucleus
Y	0036503	biological_process	ERAD pathway
Y	0042802	molecular_function	identical protein binding
Y	0042995	cellular_component	cell projection
Y	0043231	cellular_component	intracellular membrane-bounded organelle
Y	0044319	biological_process	wound healing, spreading of cells
Y	0045104	biological_process	intermediate filament cytoskeleton organization
Y	0045202	cellular_component	synapse
Y	0048489	biological_process	synaptic vesicle transport
Y	0048499	biological_process	synaptic vesicle membrane organization
Y	0051082	molecular_function	unfolded protein binding
Y	0051085	biological_process	chaperone cofactor-dependent protein refolding
Y	0051584	biological_process	regulation of dopamine uptake involved in synaptic transmission
Y	0051787	molecular_function	misfolded protein binding
Y	0061077	biological_process	chaperone-mediated protein folding
Y	0070062	cellular_component	extracellular exosome
Y	0071763	biological_process	nuclear membrane organization
Y	0140662	molecular_function	ATP-dependent protein folding chaperone
Y	1900244	biological_process	positive regulation of synaptic vesicle endocytosis
Y	2000008	biological_process	regulation of protein localization to cell surface

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	binding site for residue ATP A 401

Chain	Residue
A	LYS93
C	ASN109
C	PHE110
C	LEU272
C	CYS319
C	LYS320
A	TYR189
C	LEU69
C	PHE70
C	THR104
C	GLY105
C	THR106
C	GLY107
C	LYS108

---

site_id	AC2
Number of Residues	14
Details	binding site for residue ATP B 401

Chain	Residue
A	LEU69
A	PHE70
A	THR104
A	GLY105
A	THR106
A	GLY107
A	LYS108
A	ASN109
A	PHE110
A	LEU272
A	CYS319
A	LYS320
B	LYS93
B	TYR189

---

site_id	AC3
Number of Residues	14
Details	binding site for residue ATP C 401

Chain	Residue
C	LYS93
C	TYR189
E	LEU69
E	PHE70
E	THR104
E	GLY105
E	THR106
E	GLY107
E	LYS108
E	ASN109
E	PHE110
E	LEU272
E	CYS319
E	LYS320

---

site_id	AC4
Number of Residues	14
Details	binding site for residue ATP D 401

Chain	Residue
B	LEU69
B	PHE70
B	THR104
B	GLY105
B	THR106
B	GLY107
B	LYS108
B	ASN109
B	PHE110
B	LEU272
B	CYS319
B	LYS320
D	LYS93
D	TYR189

---

site_id	AC5
Number of Residues	14
Details	binding site for residue ATP E 401

Chain	Residue
E	LYS93
E	TYR189
G	LEU69
G	PHE70
G	THR104
G	GLY105
G	THR106
G	GLY107
G	LYS108
G	ASN109
G	PHE110
G	LEU272
G	CYS319
G	LYS320

---

site_id	AC6
Number of Residues	14
Details	binding site for residue ATP F 401

Chain	Residue
D	LEU69
D	PHE70
D	THR104
D	GLY105
D	THR106
D	GLY107
D	LYS108
D	ASN109
D	PHE110
D	LEU272
D	CYS319
D	LYS320
F	LYS93
F	TYR189

---

site_id	AC7
Number of Residues	14
Details	binding site for residue ATP G 401

Chain	Residue
G	LYS93
G	TYR189
I	LEU69
I	PHE70
I	THR104
I	GLY105
I	THR106
I	GLY107
I	LYS108
I	ASN109
I	PHE110
I	LEU272
I	CYS319
I	LYS320

---

site_id	AC8
Number of Residues	14
Details	binding site for residue ATP H 401

Chain	Residue
F	PHE70
F	THR104
F	GLY105
F	THR106
F	GLY107
F	LYS108
F	ASN109
F	PHE110
F	LEU272
F	CYS319
F	LYS320
H	LYS93
H	TYR189
F	LEU69

---

site_id	AC9
Number of Residues	14
Details	binding site for residue ATP I 401

Chain	Residue
I	LYS93
I	TYR189
K	LEU69
K	PHE70
K	THR104
K	GLY105
K	THR106
K	GLY107
K	LYS108
K	ASN109
K	PHE110
K	LEU272
K	CYS319
K	LYS320

---

site_id	AD1
Number of Residues	14
Details	binding site for residue ATP J 401

Chain	Residue
H	LEU69
H	PHE70
H	THR104
H	GLY105
H	THR106
H	GLY107
H	LYS108
H	ASN109
H	PHE110
H	LEU272
H	CYS319
H	LYS320
J	LYS93
J	TYR189

---

site_id	AD2
Number of Residues	14
Details	binding site for residue ATP K 401

Chain	Residue
K	LYS93
K	TYR189
M	LEU69
M	PHE70
M	THR104
M	GLY105
M	THR106
M	GLY107
M	LYS108
M	ASN109
M	PHE110
M	LEU272
M	CYS319
M	LYS320

---

site_id	AD3
Number of Residues	14
Details	binding site for residue ATP L 401

Chain	Residue
J	LEU69
J	PHE70
J	THR104
J	GLY105
J	THR106
J	GLY107
J	LYS108
J	ASN109
J	PHE110
J	LEU272
J	CYS319
J	LYS320
L	LYS93
L	TYR189

---

site_id	AD4
Number of Residues	14
Details	binding site for residue ATP M 401

Chain	Residue
M	LYS93
M	TYR189
O	LEU69
O	PHE70
O	THR104
O	GLY105
O	THR106
O	GLY107
O	LYS108
O	ASN109
O	PHE110
O	LEU272
O	CYS319
O	LYS320

---

site_id	AD5
Number of Residues	14
Details	binding site for residue ATP N 401

Chain	Residue
L	LEU69
L	PHE70
L	THR104
L	GLY105
L	THR106
L	GLY107
L	LYS108
L	ASN109
L	PHE110
L	LEU272
L	CYS319
L	LYS320
N	LYS93
N	TYR189

---

site_id	AD6
Number of Residues	14
Details	binding site for residue ATP O 401

Chain	Residue
O	LYS93
O	TYR189
Q	LEU69
Q	PHE70
Q	THR104
Q	GLY105
Q	THR106
Q	GLY107
Q	LYS108
Q	ASN109
Q	PHE110
Q	LEU272
Q	CYS319
Q	LYS320

---

site_id	AD7
Number of Residues	14
Details	binding site for residue ATP P 401

Chain	Residue
N	LEU69
N	PHE70
N	THR104
N	GLY105
N	THR106
N	GLY107
N	LYS108
N	ASN109
N	PHE110
N	LEU272
N	CYS319
N	LYS320
P	LYS93
P	TYR189

---

site_id	AD8
Number of Residues	14
Details	binding site for residue ATP Q 401

Chain	Residue
Q	LYS93
Q	TYR189
S	LEU69
S	PHE70
S	THR104
S	GLY105
S	THR106
S	GLY107
S	LYS108
S	ASN109
S	PHE110
S	LEU272
S	CYS319
S	LYS320

---

site_id	AD9
Number of Residues	14
Details	binding site for residue ATP R 401

Chain	Residue
P	LEU69
P	PHE70
P	THR104
P	GLY105
P	THR106
P	GLY107
P	LYS108
P	ASN109
P	PHE110
P	LEU272
P	CYS319
P	LYS320
R	LYS93
R	TYR189

---

site_id	AE1
Number of Residues	14
Details	binding site for residue ATP S 401

Chain	Residue
S	LYS93
S	TYR189
U	LEU69
U	PHE70
U	THR104
U	GLY105
U	THR106
U	GLY107
U	LYS108
U	ASN109
U	PHE110
U	LEU272
U	CYS319
U	LYS320

---

site_id	AE2
Number of Residues	14
Details	binding site for residue ATP T 401

Chain	Residue
R	LEU69
R	PHE70
R	THR104
R	GLY105
R	THR106
R	GLY107
R	LYS108
R	ASN109
R	PHE110
R	LEU272
R	CYS319
R	LYS320
T	LYS93
T	TYR189

---

site_id	AE3
Number of Residues	14
Details	binding site for residue ATP U 401

Chain	Residue
U	LYS93
U	TYR189
W	LEU69
W	PHE70
W	THR104
W	GLY105
W	THR106
W	GLY107
W	LYS108
W	ASN109
W	PHE110
W	LEU272
W	CYS319
W	LYS320

---

site_id	AE4
Number of Residues	14
Details	binding site for residue ATP V 401

Chain	Residue
T	LEU69
T	PHE70
T	THR104
T	GLY105
T	THR106
T	GLY107
T	LYS108
T	ASN109
T	PHE110
T	LEU272
T	CYS319
T	LYS320
V	LYS93
V	TYR189

---

site_id	AE5
Number of Residues	14
Details	binding site for residue ATP W 401

Chain	Residue
W	LYS93
W	TYR189
Y	LEU69
Y	PHE70
Y	THR104
Y	GLY105
Y	THR106
Y	GLY107
Y	LYS108
Y	ASN109
Y	PHE110
Y	LEU272
Y	CYS319
Y	LYS320

---

site_id	AE6
Number of Residues	14
Details	binding site for residue ATP X 401

Chain	Residue
V	LEU69
V	PHE70
V	THR104
V	GLY105
V	THR106
V	GLY107
V	LYS108
V	ASN109
V	PHE110
V	LEU272
V	CYS319
V	LYS320
X	LYS93
X	TYR189

---

site_id	AE7
Number of Residues	12
Details	binding site for residue ATP X 402

Chain	Residue
X	LEU69
X	PHE70
X	THR104
X	GLY105
X	THR106
X	GLY107
X	LYS108
X	ASN109
X	PHE110
X	LEU272
X	CYS319
X	LYS320

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	25
Details	BINDING:

Chain	Residue	Details
A	GLY102
J	GLY102
K	GLY102
L	GLY102
M	GLY102
N	GLY102
O	GLY102
P	GLY102
Q	GLY102
R	GLY102
S	GLY102
B	GLY102
T	GLY102
U	GLY102
V	GLY102
W	GLY102
X	GLY102
Y	GLY102
C	GLY102
D	GLY102
E	GLY102
F	GLY102
G	GLY102
H	GLY102
I	GLY102

---

site_id	SWS_FT_FI2
Number of Residues	50
Details	CARBOHYD: N-linked (GlcNAc...) (high mannose) asparagine => ECO:0000269|PubMed:10871631

Chain	Residue	Details
A	ASN143
E	ASN158
F	ASN143
F	ASN158
G	ASN143
G	ASN158
H	ASN143
H	ASN158
I	ASN143
I	ASN158
J	ASN143
A	ASN158
J	ASN158
K	ASN143
K	ASN158
L	ASN143
L	ASN158
M	ASN143
M	ASN158
N	ASN143
N	ASN158
O	ASN143
B	ASN143
O	ASN158
P	ASN143
P	ASN158
Q	ASN143
Q	ASN158
R	ASN143
R	ASN158
S	ASN143
S	ASN158
T	ASN143
B	ASN158
T	ASN158
U	ASN143
U	ASN158
V	ASN143
V	ASN158
W	ASN143
W	ASN158
X	ASN143
X	ASN158
Y	ASN143
C	ASN143
Y	ASN158
C	ASN158
D	ASN143
D	ASN158
E	ASN143

---