6O9X

Structure of human PARG complexed with JA2-4

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004649	molecular_function	poly(ADP-ribose) glycohydrolase activity
A	0005975	biological_process	carbohydrate metabolic process
A	0006282	biological_process	regulation of DNA repair

Functional Information from PDB Data

site_id	AC1
Number of Residues	12
Details	binding site for residue M0S A 1001

Chain	Residue
A	THR725
A	PHE900
A	PHE902
A	HOH1223
A	ILE726
A	GLU727
A	PHE738
A	GLN754
A	TYR792
A	TYR795
A	ASN869
A	GLY873

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:23251397

Chain	Residue	Details
A	ASP737

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000269|PubMed:21892188, ECO:0000269|PubMed:23251397

Chain	Residue	Details
A	GLU755
A	GLU756

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:23251397, ECO:0000269|PubMed:30472116

Chain	Residue	Details
A	ILE726
A	ASN740
A	GLN754
A	ASN869

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site_id	SWS_FT_FI4
Number of Residues	1
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9QYM2

Chain	Residue	Details
A	TYR795

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site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER448

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