6O0T

Crystal structure of selenomethionine labelled tandem SAM domains (L446M:L505M:L523M mutant) from human SARM1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003953	molecular_function	NAD+ nucleosidase activity
A	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
A	0035591	molecular_function	signaling adaptor activity
A	0048678	biological_process	response to axon injury
B	0003953	molecular_function	NAD+ nucleosidase activity
B	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
B	0035591	molecular_function	signaling adaptor activity
B	0048678	biological_process	response to axon injury
C	0003953	molecular_function	NAD+ nucleosidase activity
C	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
C	0035591	molecular_function	signaling adaptor activity
C	0048678	biological_process	response to axon injury
D	0003953	molecular_function	NAD+ nucleosidase activity
D	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
D	0035591	molecular_function	signaling adaptor activity
D	0048678	biological_process	response to axon injury
E	0003953	molecular_function	NAD+ nucleosidase activity
E	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
E	0035591	molecular_function	signaling adaptor activity
E	0048678	biological_process	response to axon injury
F	0003953	molecular_function	NAD+ nucleosidase activity
F	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
F	0035591	molecular_function	signaling adaptor activity
F	0048678	biological_process	response to axon injury
G	0003953	molecular_function	NAD+ nucleosidase activity
G	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
G	0035591	molecular_function	signaling adaptor activity
G	0048678	biological_process	response to axon injury
H	0003953	molecular_function	NAD+ nucleosidase activity
H	0034128	biological_process	negative regulation of MyD88-independent toll-like receptor signaling pathway
H	0035591	molecular_function	signaling adaptor activity
H	0048678	biological_process	response to axon injury

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000269|PubMed:30333228

Chain	Residue	Details
A	SER548
B	SER548
C	SER548
D	SER548
E	SER548
F	SER548
G	SER548
H	SER548

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site_id	SWS_FT_FI2
Number of Residues	8
Details	MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q6PDS3

Chain	Residue	Details
A	SER558
B	SER558
C	SER558
D	SER558
E	SER558
F	SER558
G	SER558
H	SER558

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