Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005085 | molecular_function | guanyl-nucleotide exchange factor activity |
| A | 0035556 | biological_process | intracellular signal transduction |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue 9JY A 601 |
| Chain | Residue |
| A | PHE277 |
| A | GLU524 |
| A | GLU525 |
| A | THR526 |
| A | THR527 |
| A | LEU535 |
| A | LEU536 |
| A | GLY538 |
| A | GLN542 |
| A | HOH709 |
| A | LEU278 |
| A | TYR280 |
| A | GLY281 |
| A | ARG282 |
| A | VAL333 |
| A | CYS369 |
| A | VAL373 |
| A | PHE523 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MES A 602 |
| Chain | Residue |
| A | GLU372 |
| A | ARG402 |
| A | LEU535 |
| A | ARG537 |
| A | TYR541 |
| A | GLN542 |
| A | HIS554 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 603 |
| Chain | Residue |
| A | CYS529 |
| A | CYS532 |
| A | HIS554 |
| A | CYS557 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 604 |
| Chain | Residue |
| A | HIS516 |
| A | CYS546 |
| A | CYS549 |
| A | CYS564 |
Functional Information from PROSITE/UniProt
| site_id | PS00479 |
| Number of Residues | 49 |
| Details | ZF_DAG_PE_1 Zinc finger phorbol-ester/DAG-type signature. HdFqmfsfeetts.CkaCqmlLrgtfyqgyr.ChrCrasaHkeClgrvpp...C |
| Chain | Residue | Details |
| A | HIS516-CYS564 | |
| site_id | PS00741 |
| Number of Residues | 26 |
| Details | DH_1 Dbl homology (DH) domain signature. LrdLLmvPMqrVlKyhLlLqELvkhT |
| Chain | Residue | Details |
| A | LEU322-THR347 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 179 |
| Details | Domain: {"description":"DH","evidences":[{"source":"PROSITE-ProRule","id":"PRU00062","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 49 |
| Details | Zinc finger: {"description":"Phorbol-ester/DAG-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00226","evidenceCode":"ECO:0000255"}]} |
