6LW1
Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002224 | biological_process | toll-like receptor signaling pathway |
| A | 0004888 | molecular_function | transmembrane signaling receptor activity |
| A | 0006955 | biological_process | immune response |
| A | 0016020 | cellular_component | membrane |
| B | 0002224 | biological_process | toll-like receptor signaling pathway |
| B | 0004888 | molecular_function | transmembrane signaling receptor activity |
| B | 0006955 | biological_process | immune response |
| B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue EX3 A 1001 |
| Chain | Residue |
| A | TYR264 |
| A | PHE408 |
| B | PHE507 |
| B | SER530 |
| B | GLN531 |
| A | ASN265 |
| A | PHE349 |
| A | PHE351 |
| A | GLU352 |
| A | LEU353 |
| A | GLN354 |
| A | VAL355 |
| A | THR406 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | binding site for residue EX3 B 1001 |
| Chain | Residue |
| A | PHE507 |
| A | SER530 |
| A | GLN531 |
| B | TYR264 |
| B | ASN265 |
| B | PHE349 |
| B | PHE351 |
| B | GLU352 |
| B | LEU353 |
| B | GLN354 |
| B | VAL355 |
| B | THR406 |
| B | PHE408 |
