6LW1
Cryo-EM structure of TLR7/Cpd-7 (DSR-139970) complex in open form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0002224 | biological_process | toll-like receptor signaling pathway |
A | 0004888 | molecular_function | transmembrane signaling receptor activity |
A | 0006955 | biological_process | immune response |
A | 0016020 | cellular_component | membrane |
B | 0002224 | biological_process | toll-like receptor signaling pathway |
B | 0004888 | molecular_function | transmembrane signaling receptor activity |
B | 0006955 | biological_process | immune response |
B | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 13 |
Details | binding site for residue EX3 A 1001 |
Chain | Residue |
A | TYR264 |
A | PHE408 |
B | PHE507 |
B | SER530 |
B | GLN531 |
A | ASN265 |
A | PHE349 |
A | PHE351 |
A | GLU352 |
A | LEU353 |
A | GLN354 |
A | VAL355 |
A | THR406 |
site_id | AC2 |
Number of Residues | 13 |
Details | binding site for residue EX3 B 1001 |
Chain | Residue |
A | PHE507 |
A | SER530 |
A | GLN531 |
B | TYR264 |
B | ASN265 |
B | PHE349 |
B | PHE351 |
B | GLU352 |
B | LEU353 |
B | GLN354 |
B | VAL355 |
B | THR406 |
B | PHE408 |