6KRZ

Crystal structure of the human adiponectin receptor 1 D208A mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016020	cellular_component	membrane
B	0016020	cellular_component	membrane
C	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue PO4 A 401

Chain	Residue
A	SER120
A	PHE121
A	ARG122
E	HIS30

---

site_id	AC2
Number of Residues	15
Details	binding site for residue OLA A 402

Chain	Residue
A	MET306
A	TYR310
A	ALA314
A	TYR317
A	PHE340
A	VAL344
A	ALA347
A	HIS351
A	OLA403
A	HOH507
A	LEU215
A	SER219
A	ALA268
A	PHE271
A	LEU272

---

site_id	AC3
Number of Residues	8
Details	binding site for residue OLA A 403

Chain	Residue
A	SER219
A	PHE220
A	GLY275
A	LEU276
A	PHE303
A	TYR310
A	HIS351
A	OLA402

---

site_id	AC4
Number of Residues	4
Details	binding site for residue ZN A 404

Chain	Residue
A	SER187
A	HIS191
A	HIS337
A	HIS341

---

site_id	AC5
Number of Residues	4
Details	binding site for residue PO4 B 401

Chain	Residue
B	SER120
B	PHE121
B	ARG122
G	HIS30

---

site_id	AC6
Number of Residues	5
Details	binding site for residue ZN B 402

Chain	Residue
B	SER187
B	HIS191
B	HIS337
B	HIS341
B	HOH515

---

site_id	AC7
Number of Residues	3
Details	binding site for residue PO4 C 401

Chain	Residue
C	SER120
C	PHE121
I	HIS30

---

site_id	AC8
Number of Residues	5
Details	binding site for residue ZN C 402

Chain	Residue
C	SER187
C	HIS191
C	HIS337
C	HIS341
C	OLB404

---

site_id	AC9
Number of Residues	4
Details	binding site for residue OLB C 403

Chain	Residue
C	TYR209
C	ALA253
C	ARG267
C	GLY275

---

site_id	AD1
Number of Residues	9
Details	binding site for residue OLB C 404

Chain	Residue
C	ASP106
C	GLU134
C	PHE190
C	HIS191
C	TYR209
C	ILE212
C	ILE216
C	TYR310
C	ZN402

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	60
Details	TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	ASN137-LEU157
B	ASN137-LEU157
C	ASN137-LEU157

---

site_id	SWS_FT_FI2
Number of Residues	147
Details	TOPO_DOM: Extracellular => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	ARG158-LYS170
C	TYR225-PRO234
C	THR286-GLY298
C	GLN359-LEU375
A	TYR225-PRO234
A	THR286-GLY298
A	GLN359-LEU375
B	ARG158-LYS170
B	TYR225-PRO234
B	THR286-GLY298
B	GLN359-LEU375
C	ARG158-LYS170

---

site_id	SWS_FT_FI3
Number of Residues	60
Details	TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	VAL171-HIS191
B	VAL171-HIS191
C	VAL171-HIS191

---

site_id	SWS_FT_FI4
Number of Residues	108
Details	TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	THR192-THR203
A	ASP256-ARG264
A	ARG320-HIS337
B	THR192-THR203
B	ASP256-ARG264
B	ARG320-HIS337
C	THR192-THR203
C	ASP256-ARG264
C	ARG320-HIS337

---

site_id	SWS_FT_FI5
Number of Residues	60
Details	TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	PHE204-LEU224
B	PHE204-LEU224
C	PHE204-LEU224

---

site_id	SWS_FT_FI6
Number of Residues	60
Details	TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	ARG235-TRP255
B	ARG235-TRP255
C	ARG235-TRP255

---

site_id	SWS_FT_FI7
Number of Residues	60
Details	TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	GLN265-PHE285
B	GLN265-PHE285
C	GLN265-PHE285

---

site_id	SWS_FT_FI8
Number of Residues	60
Details	TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	GLN299-ALA319
B	GLN299-ALA319
C	GLN299-ALA319

---

site_id	SWS_FT_FI9
Number of Residues	60
Details	TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	GLN338-LEU358
B	GLN338-LEU358
C	GLN338-LEU358

---

site_id	SWS_FT_FI10
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:25855295

Chain	Residue	Details
A	HIS191
A	HIS337
A	HIS341
B	HIS191
B	HIS337
B	HIS341
C	HIS191
C	HIS337
C	HIS341

---