6K0R
Ruvbl1-Ruvbl2 with truncated domain II in complex with phosphorylated Cordycepin
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005524 | molecular_function | ATP binding |
| A | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0016887 | molecular_function | ATP hydrolysis activity |
| C | 0005524 | molecular_function | ATP binding |
| C | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| C | 0016887 | molecular_function | ATP hydrolysis activity |
| D | 0005524 | molecular_function | ATP binding |
| D | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| D | 0016887 | molecular_function | ATP hydrolysis activity |
| E | 0005524 | molecular_function | ATP binding |
| E | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| E | 0016887 | molecular_function | ATP hydrolysis activity |
| F | 0005524 | molecular_function | ATP binding |
| F | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| F | 0016887 | molecular_function | ATP hydrolysis activity |
| G | 0005524 | molecular_function | ATP binding |
| G | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| G | 0016887 | molecular_function | ATP hydrolysis activity |
| H | 0005524 | molecular_function | ATP binding |
| H | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| H | 0016887 | molecular_function | ATP hydrolysis activity |
| I | 0005524 | molecular_function | ATP binding |
| I | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| I | 0016887 | molecular_function | ATP hydrolysis activity |
| J | 0005524 | molecular_function | ATP binding |
| J | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| J | 0016887 | molecular_function | ATP hydrolysis activity |
| K | 0005524 | molecular_function | ATP binding |
| K | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| K | 0016887 | molecular_function | ATP hydrolysis activity |
| L | 0005524 | molecular_function | ATP binding |
| L | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| L | 0016887 | molecular_function | ATP hydrolysis activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue ADP A 501 |
| Chain | Residue |
| A | SER17 |
| A | LYS76 |
| A | THR77 |
| A | ALA78 |
| A | TYR366 |
| A | ILE374 |
| A | LEU403 |
| A | ARG404 |
| A | HIS18 |
| A | HIS20 |
| A | GLY38 |
| A | LEU39 |
| A | VAL40 |
| A | GLY73 |
| A | THR74 |
| A | GLY75 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue CUU B 501 |
| Chain | Residue |
| B | SER17 |
| B | HIS18 |
| B | HIS20 |
| B | GLY38 |
| B | LEU39 |
| B | VAL40 |
| B | GLY73 |
| B | THR74 |
| B | GLY75 |
| B | LYS76 |
| B | THR77 |
| B | ALA78 |
| B | TYR366 |
| B | ILE374 |
| B | LEU403 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | binding site for residue CUU C 501 |
| Chain | Residue |
| C | SER17 |
| C | HIS18 |
| C | HIS20 |
| C | GLY38 |
| C | LEU39 |
| C | VAL40 |
| C | PRO72 |
| C | GLY73 |
| C | THR74 |
| C | GLY75 |
| C | LYS76 |
| C | THR77 |
| C | ALA78 |
| C | TYR366 |
| C | ILE374 |
| C | LEU403 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue CUU D 501 |
| Chain | Residue |
| D | HIS27 |
| D | MET46 |
| D | VAL47 |
| D | GLY80 |
| D | THR81 |
| D | GLY82 |
| D | LYS83 |
| D | THR84 |
| D | ALA85 |
| D | TYR362 |
| D | ILE370 |
| D | LEU399 |
| D | ILE403 |
| D | MG502 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG D 502 |
| Chain | Residue |
| D | CUU501 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue 3AT E 501 |
| Chain | Residue |
| A | ASP356 |
| E | ALA24 |
| E | HIS27 |
| E | GLY45 |
| E | MET46 |
| E | VAL47 |
| E | GLY80 |
| E | THR81 |
| E | GLY82 |
| E | LYS83 |
| E | THR84 |
| E | ALA85 |
| E | ASP299 |
| E | TYR362 |
| E | ILE370 |
| E | LEU399 |
| E | ILE403 |
| site_id | AC7 |
| Number of Residues | 12 |
| Details | binding site for residue CUU F 501 |
| Chain | Residue |
| F | ALA24 |
| F | HIS25 |
| F | HIS27 |
| F | GLY45 |
| F | MET46 |
| F | VAL47 |
| F | GLY80 |
| F | THR81 |
| F | GLY82 |
| F | LYS83 |
| F | THR84 |
| F | TYR362 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | binding site for residue CUU G 501 |
| Chain | Residue |
| G | GLY75 |
| G | LYS76 |
| G | THR77 |
| G | ALA78 |
| G | TYR366 |
| G | ILE374 |
| G | LEU403 |
| G | SER17 |
| G | HIS18 |
| G | HIS20 |
| G | GLY38 |
| G | LEU39 |
| G | VAL40 |
| G | GLY73 |
| G | THR74 |
| site_id | AC9 |
| Number of Residues | 14 |
| Details | binding site for residue CUU H 501 |
| Chain | Residue |
| H | SER17 |
| H | HIS18 |
| H | HIS20 |
| H | GLY38 |
| H | LEU39 |
| H | VAL40 |
| H | GLY73 |
| H | THR74 |
| H | GLY75 |
| H | LYS76 |
| H | THR77 |
| H | ASP302 |
| H | TYR366 |
| H | ILE374 |
| site_id | AD1 |
| Number of Residues | 16 |
| Details | binding site for residue CUU I 501 |
| Chain | Residue |
| I | SER17 |
| I | HIS18 |
| I | HIS20 |
| I | GLY38 |
| I | LEU39 |
| I | VAL40 |
| I | PRO72 |
| I | GLY73 |
| I | THR74 |
| I | GLY75 |
| I | LYS76 |
| I | THR77 |
| I | ALA78 |
| I | TYR366 |
| I | ILE374 |
| I | LEU403 |
| site_id | AD2 |
| Number of Residues | 15 |
| Details | binding site for residue 3AT J 501 |
| Chain | Residue |
| J | HIS25 |
| J | HIS27 |
| J | GLY45 |
| J | MET46 |
| J | VAL47 |
| J | GLN49 |
| J | GLY80 |
| J | THR81 |
| J | GLY82 |
| J | LYS83 |
| J | THR84 |
| J | ASP299 |
| J | TYR362 |
| J | LEU399 |
| J | HOH601 |
| site_id | AD3 |
| Number of Residues | 14 |
| Details | binding site for residue CUU K 501 |
| Chain | Residue |
| K | ALA24 |
| K | HIS25 |
| K | HIS27 |
| K | GLY45 |
| K | MET46 |
| K | VAL47 |
| K | GLY80 |
| K | THR81 |
| K | GLY82 |
| K | LYS83 |
| K | THR84 |
| K | TYR362 |
| K | ILE370 |
| K | LEU399 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue CU0 L 501 |
| Chain | Residue |
| L | HIS25 |
| L | GLY80 |
| L | THR81 |
| L | GLY82 |
| L | LYS83 |
| L | THR84 |
| L | ALA85 |
| L | LEU399 |
| L | ILE403 |
| L | MG502 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue MG L 502 |
| Chain | Residue |
| L | CU0501 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | BINDING: |
| Chain | Residue | Details |
| D | GLY77 | |
| E | GLY77 | |
| F | GLY77 | |
| J | GLY77 | |
| K | GLY77 | |
| L | GLY77 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: N-acetylalanine => ECO:0000269|Ref.14, ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22814378, ECO:0007744|PubMed:25944712 |
| Chain | Residue | Details |
| D | ALA2 | |
| E | ALA2 | |
| F | ALA2 | |
| J | ALA2 | |
| K | ALA2 | |
| L | ALA2 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| D | SER437 | |
| E | SER437 | |
| F | SER437 | |
| J | SER437 | |
| K | SER437 | |
| L | SER437 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 24 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| K | LYS444 | |
| K | LYS456 | |
| L | LYS9 | |
| L | LYS444 | |
| L | LYS456 | |
| A | LYS445 | |
| C | LYS445 | |
| H | LYS445 | |
| D | LYS9 | |
| D | LYS444 | |
| D | LYS456 | |
| E | LYS9 | |
| E | LYS444 | |
| E | LYS456 | |
| F | LYS9 | |
| F | LYS444 | |
| F | LYS456 | |
| J | LYS9 | |
| J | LYS444 | |
| J | LYS456 | |
| K | LYS9 |
