6I9C
Structure of the OTU domain of OTULIN G281R mutant
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 401 |
| Chain | Residue |
| A | ASP268 |
| A | GLY270 |
| A | ARG274 |
| A | GOL402 |
| A | HOH533 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 402 |
| Chain | Residue |
| A | HOH606 |
| A | TYR165 |
| A | TRP167 |
| A | ASN245 |
| A | GOL401 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 403 |
| Chain | Residue |
| A | GLU95 |
| A | TRP96 |
| A | ARG97 |
| A | LYS116 |
| A | GLN303 |
| A | THR331 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 404 |
| Chain | Residue |
| A | ASN127 |
| A | LYS233 |
| A | HIS276 |
| A | LEU277 |
| A | GLN279 |
| A | HOH605 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue CL A 405 |
| Chain | Residue |
| A | LYS94 |
| A | VAL318 |
| A | HOH565 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000269|PubMed:23708998, ECO:0000269|PubMed:23746843, ECO:0007744|PDB:3ZNZ, ECO:0007744|PDB:4KSL |
| Chain | Residue | Details |
| A | ASP126 | |
| A | HIS339 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:23708998, ECO:0000269|PubMed:23746843, ECO:0000269|PubMed:24726327, ECO:0007744|PDB:3ZNZ, ECO:0007744|PDB:4KSL |
| Chain | Residue | Details |
| A | CYS129 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: Linear diubiquitin binding => ECO:0000269|PubMed:23708998, ECO:0000269|PubMed:23746843, ECO:0007744|PDB:3ZNZ, ECO:0007744|PDB:4KSK, ECO:0007744|PDB:4KSL |
| Chain | Residue | Details |
| A | GLU314 |
