6I29

X-ray structure of the p53-MDM2 inhibitor NMI801 bound to HDM2 at 2.1A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005634	cellular_component	nucleus
A	0043066	biological_process	negative regulation of apoptotic process
A	0051726	biological_process	regulation of cell cycle

Functional Information from PDB Data

site_id	AC1
Number of Residues	15
Details	binding site for residue H0W A 201

Chain	Residue
A	GLN44
A	MET62
A	GLN72
A	VAL93
A	HIS96
A	ILE99
A	HOH319
A	LYS51
A	GLU52
A	LEU54
A	PHE55
A	TYR56
A	LEU57
A	GLY58
A	ILE61

---