6HYU

Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003676	molecular_function	nucleic acid binding
A	0003724	molecular_function	RNA helicase activity
A	0005524	molecular_function	ATP binding
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003676	molecular_function	nucleic acid binding
C	0003724	molecular_function	RNA helicase activity
C	0005524	molecular_function	ATP binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue EDO A 1301

Chain	Residue
A	TYR748
A	LYS750

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Functional Information from PROSITE/UniProt

site_id	PS00690
Number of Residues	10
Details	DEAH_ATP_HELICASE DEAH-box subfamily ATP-dependent helicases signature. AiIMLDEAHE

Chain	Residue	Details
A	ALA680-GLU689

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	326
Details	Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	180
Details	Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Motif: {"description":"DEAH box"}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	14
Details	Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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