6HQU
Humanised RadA mutant HumRadA22 in complex with a recombined BRC repeat 8-2
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006259 | biological_process | DNA metabolic process |
| A | 0006281 | biological_process | DNA repair |
| A | 0006310 | biological_process | DNA recombination |
| A | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| A | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003684 | molecular_function | damaged DNA binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006259 | biological_process | DNA metabolic process |
| B | 0006281 | biological_process | DNA repair |
| B | 0006310 | biological_process | DNA recombination |
| B | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| B | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| C | 0003677 | molecular_function | DNA binding |
| C | 0003684 | molecular_function | damaged DNA binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0006259 | biological_process | DNA metabolic process |
| C | 0006281 | biological_process | DNA repair |
| C | 0006310 | biological_process | DNA recombination |
| C | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| C | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003684 | molecular_function | damaged DNA binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0006259 | biological_process | DNA metabolic process |
| D | 0006281 | biological_process | DNA repair |
| D | 0006310 | biological_process | DNA recombination |
| D | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| D | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003684 | molecular_function | damaged DNA binding |
| E | 0005524 | molecular_function | ATP binding |
| E | 0006259 | biological_process | DNA metabolic process |
| E | 0006281 | biological_process | DNA repair |
| E | 0006310 | biological_process | DNA recombination |
| E | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| E | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| F | 0003677 | molecular_function | DNA binding |
| F | 0003684 | molecular_function | damaged DNA binding |
| F | 0005524 | molecular_function | ATP binding |
| F | 0006259 | biological_process | DNA metabolic process |
| F | 0006281 | biological_process | DNA repair |
| F | 0006310 | biological_process | DNA recombination |
| F | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| F | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| G | 0003677 | molecular_function | DNA binding |
| G | 0003684 | molecular_function | damaged DNA binding |
| G | 0005524 | molecular_function | ATP binding |
| G | 0006259 | biological_process | DNA metabolic process |
| G | 0006281 | biological_process | DNA repair |
| G | 0006310 | biological_process | DNA recombination |
| G | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| G | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
| H | 0003677 | molecular_function | DNA binding |
| H | 0003684 | molecular_function | damaged DNA binding |
| H | 0005524 | molecular_function | ATP binding |
| H | 0006259 | biological_process | DNA metabolic process |
| H | 0006281 | biological_process | DNA repair |
| H | 0006310 | biological_process | DNA recombination |
| H | 0008094 | molecular_function | ATP-dependent activity, acting on DNA |
| H | 0140664 | molecular_function | ATP-dependent DNA damage sensor activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue ADP A 401 |
| Chain | Residue |
| A | GLU139 |
| A | ARG323 |
| A | ILE342 |
| A | MG402 |
| A | HOH502 |
| A | HOH504 |
| A | HOH509 |
| A | HOH534 |
| C | GLU184 |
| C | GLU344 |
| C | ADP401 |
| A | GLY141 |
| A | SER142 |
| A | GLY143 |
| A | LYS144 |
| A | THR145 |
| A | GLN146 |
| A | ARG181 |
| A | GLU184 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 402 |
| Chain | Residue |
| A | THR145 |
| A | ADP401 |
| A | HOH501 |
| A | HOH502 |
| A | HOH504 |
| A | HOH532 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | binding site for residue ADP B 401 |
| Chain | Residue |
| B | PHE140 |
| B | GLY141 |
| B | SER142 |
| B | GLY143 |
| B | LYS144 |
| B | THR145 |
| B | GLN146 |
| B | ARG181 |
| B | ARG323 |
| B | ILE342 |
| B | MG402 |
| B | HOH520 |
| B | HOH521 |
| B | HOH525 |
| B | HOH526 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 402 |
| Chain | Residue |
| B | THR145 |
| B | ADP401 |
| B | HOH506 |
| B | HOH520 |
| B | HOH525 |
| B | HOH526 |
| site_id | AC5 |
| Number of Residues | 20 |
| Details | binding site for residue ADP C 401 |
| Chain | Residue |
| A | GLU344 |
| A | ADP401 |
| C | GLU139 |
| C | GLY141 |
| C | SER142 |
| C | GLY143 |
| C | LYS144 |
| C | THR145 |
| C | GLN146 |
| C | ARG181 |
| C | GLU184 |
| C | ARG323 |
| C | ILE342 |
| C | THR343 |
| C | MG402 |
| C | HOH505 |
| C | HOH507 |
| C | HOH515 |
| C | HOH519 |
| C | HOH522 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue MG C 402 |
| Chain | Residue |
| C | THR145 |
| C | ADP401 |
| C | HOH501 |
| C | HOH505 |
| C | HOH507 |
| C | HOH515 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | binding site for residue ADP D 401 |
| Chain | Residue |
| D | GLU139 |
| D | PHE140 |
| D | GLY141 |
| D | SER142 |
| D | GLY143 |
| D | LYS144 |
| D | THR145 |
| D | GLN146 |
| D | ARG181 |
| D | ARG323 |
| D | ILE342 |
| D | MG402 |
| D | HOH505 |
| D | HOH506 |
| D | HOH510 |
| D | HOH527 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue MG D 402 |
| Chain | Residue |
| D | THR145 |
| D | ADP401 |
| D | HOH504 |
| D | HOH505 |
| D | HOH510 |
| D | HOH512 |
| site_id | AC9 |
| Number of Residues | 17 |
| Details | binding site for residue ADP E 401 |
| Chain | Residue |
| E | LYS144 |
| E | THR145 |
| E | GLN146 |
| E | ARG181 |
| E | GLU184 |
| E | ARG323 |
| E | ILE342 |
| E | MG402 |
| E | HOH502 |
| E | HOH506 |
| E | HOH517 |
| E | HOH521 |
| E | GLU139 |
| E | PHE140 |
| E | GLY141 |
| E | SER142 |
| E | GLY143 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG E 402 |
| Chain | Residue |
| E | THR145 |
| E | ADP401 |
| E | HOH502 |
| E | HOH512 |
| E | HOH514 |
| E | HOH517 |
| site_id | AD2 |
| Number of Residues | 12 |
| Details | binding site for residue ADP F 401 |
| Chain | Residue |
| F | GLU139 |
| F | GLY141 |
| F | SER142 |
| F | GLY143 |
| F | LYS144 |
| F | THR145 |
| F | GLN146 |
| F | ARG181 |
| F | GLU184 |
| F | ARG323 |
| F | ILE342 |
| F | MG402 |
| site_id | AD3 |
| Number of Residues | 2 |
| Details | binding site for residue MG F 402 |
| Chain | Residue |
| F | THR145 |
| F | ADP401 |
| site_id | AD4 |
| Number of Residues | 13 |
| Details | binding site for residue ADP G 401 |
| Chain | Residue |
| G | GLU139 |
| G | GLY141 |
| G | SER142 |
| G | GLY143 |
| G | LYS144 |
| G | THR145 |
| G | GLN146 |
| G | ARG181 |
| G | GLU184 |
| G | ARG323 |
| G | ILE342 |
| G | MG402 |
| G | HOH504 |
| site_id | AD5 |
| Number of Residues | 3 |
| Details | binding site for residue MG G 402 |
| Chain | Residue |
| G | THR145 |
| G | ADP401 |
| G | HOH504 |
| site_id | AD6 |
| Number of Residues | 12 |
| Details | binding site for residue ADP H 401 |
| Chain | Residue |
| H | GLU139 |
| H | PHE140 |
| H | GLY141 |
| H | SER142 |
| H | GLY143 |
| H | LYS144 |
| H | THR145 |
| H | GLN146 |
| H | ARG181 |
| H | ARG323 |
| H | ILE342 |
| H | MG402 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue MG H 402 |
| Chain | Residue |
| H | THR145 |
| H | ADP401 |
