6G5J
Secreted phospholipase A2 type X in complex with ligand
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004623 | molecular_function | phospholipase A2 activity |
| A | 0005509 | molecular_function | calcium ion binding |
| A | 0006644 | biological_process | phospholipid metabolic process |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0050482 | biological_process | arachidonate secretion |
| B | 0004623 | molecular_function | phospholipase A2 activity |
| B | 0005509 | molecular_function | calcium ion binding |
| B | 0006644 | biological_process | phospholipid metabolic process |
| B | 0016042 | biological_process | lipid catabolic process |
| B | 0050482 | biological_process | arachidonate secretion |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 201 |
| Chain | Residue |
| A | PHE26 |
| A | GLY28 |
| A | GLY30 |
| A | ASP47 |
| A | EM8202 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | binding site for residue EM8 A 202 |
| Chain | Residue |
| A | TYR20 |
| A | MET21 |
| A | PHE26 |
| A | CYS27 |
| A | GLY28 |
| A | LEU29 |
| A | GLY30 |
| A | CYS43 |
| A | HIS46 |
| A | ASP47 |
| A | ILE94 |
| A | CA201 |
| A | HOH323 |
| A | HOH356 |
| B | LEU114 |
| A | ILE2 |
| A | LEU5 |
| A | ALA6 |
| A | PRO17 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | binding site for residue EM8 A 203 |
| Chain | Residue |
| A | ARG15 |
| A | THR16 |
| A | ILE18 |
| A | ALA19 |
| A | TYR103 |
| A | PHE109 |
| A | HOH316 |
| B | LEU105 |
| B | LEU108 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 204 |
| Chain | Residue |
| A | ARG64 |
| A | SER66 |
| A | PRO78 |
| A | GLU80 |
| B | GLN68 |
| B | LEU75 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue DMS A 205 |
| Chain | Residue |
| A | LYS22 |
| A | GLY24 |
| A | CYS25 |
| A | CYS27 |
| A | GLY28 |
| A | LEU29 |
| A | GLY30 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 201 |
| Chain | Residue |
| B | PHE26 |
| B | GLY28 |
| B | GLY30 |
| B | ASP47 |
| B | EM8202 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue EM8 B 202 |
| Chain | Residue |
| A | PHE113 |
| B | ILE2 |
| B | LEU5 |
| B | PRO17 |
| B | ILE18 |
| B | TYR20 |
| B | MET21 |
| B | PHE26 |
| B | CYS27 |
| B | GLY28 |
| B | LEU29 |
| B | GLY30 |
| B | CYS43 |
| B | HIS46 |
| B | ASP47 |
| B | ILE94 |
| B | CA201 |
| B | HOH319 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"12161451","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"12161451","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1LE6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1LE7","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
