Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| B | 0004672 | molecular_function | protein kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | binding site for residue EKT A 901 |
| Chain | Residue |
| A | LEU551 |
| A | LYS677 |
| A | SER698 |
| A | HOH1012 |
| A | HOH1063 |
| A | LEU579 |
| A | LYS581 |
| A | GLN626 |
| A | GLU627 |
| A | PHE628 |
| A | VAL629 |
| A | LYS630 |
| A | GLY632 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 902 |
| Chain | Residue |
| A | ASN782 |
| A | LEU783 |
| A | ASN786 |
| A | ASP804 |
| A | HOH1048 |
| A | HOH1062 |
| B | LEU604 |
| B | SER605 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 903 |
| Chain | Residue |
| A | ASN786 |
| A | ALA800 |
| B | SER605 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 904 |
| Chain | Residue |
| A | ALA781 |
| A | ASN782 |
| B | GLU666 |
| B | ASN667 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 905 |
| Chain | Residue |
| A | TRP744 |
| A | LEU772 |
| A | PRO773 |
| A | ALA774 |
| A | ALA781 |
| A | ILE784 |
| A | ASN785 |
| A | HOH1069 |
| site_id | AC6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 906 |
| Chain | Residue |
| A | LYS752 |
| A | SER755 |
| A | HOH1120 |
| A | HOH1150 |
| B | ILE546 |
| B | PHE547 |
| B | ASN548 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 907 |
| Chain | Residue |
| A | ASP569 |
| A | HIS770 |
| A | HOH1022 |
| A | HOH1065 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue EDO A 908 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 909 |
| Chain | Residue |
| A | ASN673 |
| A | ARG715 |
| A | TRP718 |
| A | HOH1031 |
| site_id | AD1 |
| Number of Residues | 15 |
| Details | binding site for residue EKT B 901 |
| Chain | Residue |
| B | LEU551 |
| B | GLY552 |
| B | LEU579 |
| B | LYS581 |
| B | GLN626 |
| B | GLU627 |
| B | PHE628 |
| B | VAL629 |
| B | LYS630 |
| B | GLY632 |
| B | LYS677 |
| B | SER698 |
| B | HOH1014 |
| B | HOH1027 |
| B | HOH1028 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 902 |
| Chain | Residue |
| B | THR555 |
| B | ILE711 |
| B | ARG715 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 903 |
| Chain | Residue |
| A | SER605 |
| B | LEU783 |
| B | ASN786 |
| B | PRO796 |
| B | ALA800 |
| B | HOH1003 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 904 |
| Chain | Residue |
| B | GLU665 |
| B | GLU666 |
| B | ARG799 |
| B | HOH1066 |
| site_id | AD5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 905 |
| Chain | Residue |
| B | TRP718 |
| B | LYS752 |
| B | HOH1002 |
| B | HOH1013 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Site: {"description":"Breakpoint for translocation to form PCM1-JAK2 fusion protein"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
