6FXN

Crystal structure of human BAFF in complex with Fab fragment of anti-BAFF antibody belimumab

Replaces:  6ERX

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005164	molecular_function	tumor necrosis factor receptor binding
A	0006955	biological_process	immune response
A	0016020	cellular_component	membrane
B	0005164	molecular_function	tumor necrosis factor receptor binding
B	0006955	biological_process	immune response
B	0016020	cellular_component	membrane
C	0005164	molecular_function	tumor necrosis factor receptor binding
C	0006955	biological_process	immune response
C	0016020	cellular_component	membrane
J	0005164	molecular_function	tumor necrosis factor receptor binding
J	0006955	biological_process	immune response
J	0016020	cellular_component	membrane
K	0005164	molecular_function	tumor necrosis factor receptor binding
K	0006955	biological_process	immune response
K	0016020	cellular_component	membrane
L	0005164	molecular_function	tumor necrosis factor receptor binding
L	0006955	biological_process	immune response
L	0016020	cellular_component	membrane

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
D	TYR204-HIS210
E	TYR193-HIS199

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	834
Details	Domain: {"description":"THD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01387","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	6
Details	Glycosylation: {"description":"N-linked (GlcNAc...) (high mannose) asparagine"}

Chain

Residue

Details

---