Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| A | 0016032 | biological_process | viral process |
| A | 0019082 | biological_process | viral protein processing |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 201 |
| Chain | Residue |
| A | ALA135 |
| A | SER156 |
| A | TYR183 |
| A | HOH306 |
| A | HOH351 |
| B | HOH309 |
| B | HOH314 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | GLU65 |
| A | PRO66 |
| A | TYR72 |
| A | HOH348 |
| A | HOH392 |
| A | HOH402 |
| A | ARG61 |
| A | GLU64 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 203 |
| Chain | Residue |
| A | TRP70 |
| A | HOH309 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | GLU87 |
| A | GLU93 |
| A | LEU94 |
| A | HIS95 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 205 |
| Chain | Residue |
| A | TYR42 |
| A | ARG61 |
| A | SER73 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 206 |
| Chain | Residue |
| A | LEU80 |
| A | LYS84 |
| A | HIS95 |
| A | HOH347 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 207 |
| Chain | Residue |
| A | LYS144 |
| A | TRP170 |
| A | HOH305 |
| site_id | AC8 |
| Number of Residues | 8 |
| Details | binding site for residue GOL B 201 |
| Chain | Residue |
| A | GLU93 |
| B | LYS108 |
| B | ASP120 |
| B | TRP123 |
| B | HOH321 |
| B | HOH328 |
| B | HOH335 |
| B | HOH362 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"For leader protease activity","evidences":[{"source":"PubMed","id":"29463763","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9857201","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For leader protease activity","evidences":[{"source":"PubMed","id":"29463763","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Site: {"description":"Interacts with activating enzyme","evidences":[{"evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 746 |
| Chain | Residue | Details |
| A | ASN46 | electrostatic stabiliser, polar interaction |
| A | CYS51 | electrostatic stabiliser, polar interaction |
| A | HIS148 | hydrogen bond acceptor, proton acceptor, proton donor |
| A | ASP163 | electrostatic stabiliser, hydrogen bond donor |
