Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6FF4

human Bact spliceosome core structure

Functional Information from GO Data

Chain	GOid	namespace	contents
1	0000398	biological_process	mRNA splicing, via spliceosome
1	0003676	molecular_function	nucleic acid binding
1	0003723	molecular_function	RNA binding
1	0005515	molecular_function	protein binding
1	0005634	cellular_component	nucleus
1	0005654	cellular_component	nucleoplasm
1	0005681	cellular_component	spliceosomal complex
1	0005686	cellular_component	U2 snRNP
1	0005730	cellular_component	nucleolus
1	0005783	cellular_component	endoplasmic reticulum
1	0006397	biological_process	mRNA processing
1	0008380	biological_process	RNA splicing
1	0031965	cellular_component	nuclear membrane
1	0071005	cellular_component	U2-type precatalytic spliceosome
1	0071011	cellular_component	precatalytic spliceosome
1	1903241	biological_process	U2-type prespliceosome assembly
3	0000398	biological_process	mRNA splicing, via spliceosome
3	0003723	molecular_function	RNA binding
3	0005515	molecular_function	protein binding
3	0005634	cellular_component	nucleus
3	0005654	cellular_component	nucleoplasm
3	0005681	cellular_component	spliceosomal complex
3	0005684	cellular_component	U2-type spliceosomal complex
3	0005686	cellular_component	U2 snRNP
3	0006397	biological_process	mRNA processing
3	0008380	biological_process	RNA splicing
3	0070274	cellular_component	RES complex
3	0071005	cellular_component	U2-type precatalytic spliceosome
3	1903241	biological_process	U2-type prespliceosome assembly
7	0000245	biological_process	spliceosomal complex assembly
7	0000389	biological_process	mRNA 3'-splice site recognition
7	0000398	biological_process	mRNA splicing, via spliceosome
7	0003676	molecular_function	nucleic acid binding
7	0003723	molecular_function	RNA binding
7	0005515	molecular_function	protein binding
7	0005634	cellular_component	nucleus
7	0005654	cellular_component	nucleoplasm
7	0005681	cellular_component	spliceosomal complex
7	0005684	cellular_component	U2-type spliceosomal complex
7	0005686	cellular_component	U2 snRNP
7	0006397	biological_process	mRNA processing
7	0008270	molecular_function	zinc ion binding
7	0008380	biological_process	RNA splicing
7	0010976	biological_process	positive regulation of neuron projection development
7	0016607	cellular_component	nuclear speck
7	0046872	molecular_function	metal ion binding
7	0071004	cellular_component	U2-type prespliceosome
7	0071005	cellular_component	U2-type precatalytic spliceosome
7	0071013	cellular_component	catalytic step 2 spliceosome
7	1903241	biological_process	U2-type prespliceosome assembly
8	0000398	biological_process	mRNA splicing, via spliceosome
8	0003723	molecular_function	RNA binding
8	0005515	molecular_function	protein binding
8	0005634	cellular_component	nucleus
8	0005654	cellular_component	nucleoplasm
8	0005681	cellular_component	spliceosomal complex
8	0005684	cellular_component	U2-type spliceosomal complex
8	0005686	cellular_component	U2 snRNP
8	0005689	cellular_component	U12-type spliceosomal complex
8	0006397	biological_process	mRNA processing
8	0008380	biological_process	RNA splicing
8	0016607	cellular_component	nuclear speck
8	0071005	cellular_component	U2-type precatalytic spliceosome
8	0071011	cellular_component	precatalytic spliceosome
8	0071013	cellular_component	catalytic step 2 spliceosome
8	1903241	biological_process	U2-type prespliceosome assembly
A	0000244	biological_process	spliceosomal tri-snRNP complex assembly
A	0000375	biological_process	RNA splicing, via transesterification reactions
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005682	cellular_component	U5 snRNP
A	0006397	biological_process	mRNA processing
A	0008233	molecular_function	peptidase activity
A	0008237	molecular_function	metallopeptidase activity
A	0008380	biological_process	RNA splicing
A	0016020	cellular_component	membrane
A	0016607	cellular_component	nuclear speck
A	0017070	molecular_function	U6 snRNA binding
A	0030532	cellular_component	small nuclear ribonucleoprotein complex
A	0030619	molecular_function	U1 snRNA binding
A	0030620	molecular_function	U2 snRNA binding
A	0030623	molecular_function	U5 snRNA binding
A	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
A	0070530	molecular_function	K63-linked polyubiquitin modification-dependent protein binding
A	0071005	cellular_component	U2-type precatalytic spliceosome
A	0071006	cellular_component	U2-type catalytic step 1 spliceosome
A	0071007	cellular_component	U2-type catalytic step 2 spliceosome
A	0071013	cellular_component	catalytic step 2 spliceosome
A	0071222	biological_process	cellular response to lipopolysaccharide
A	0071356	biological_process	cellular response to tumor necrosis factor
A	0097157	molecular_function	pre-mRNA intronic binding
A	0140492	molecular_function	metal-dependent deubiquitinase activity
B	0000398	biological_process	mRNA splicing, via spliceosome
B	0003723	molecular_function	RNA binding
B	0003924	molecular_function	GTPase activity
B	0005515	molecular_function	protein binding
B	0005525	molecular_function	GTP binding
B	0005634	cellular_component	nucleus
B	0005654	cellular_component	nucleoplasm
B	0005681	cellular_component	spliceosomal complex
B	0005829	cellular_component	cytosol
B	0006397	biological_process	mRNA processing
B	0008380	biological_process	RNA splicing
B	0015030	cellular_component	Cajal body
B	0016020	cellular_component	membrane
B	0016607	cellular_component	nuclear speck
B	0030623	molecular_function	U5 snRNA binding
B	0042220	biological_process	response to cocaine
B	0043231	cellular_component	intracellular membrane-bounded organelle
B	0046540	cellular_component	U4/U6 x U5 tri-snRNP complex
B	0071005	cellular_component	U2-type precatalytic spliceosome
B	0071007	cellular_component	U2-type catalytic step 2 spliceosome
B	0071013	cellular_component	catalytic step 2 spliceosome
B	0071466	biological_process	cellular response to xenobiotic stimulus
C	0000122	biological_process	negative regulation of transcription by RNA polymerase II
C	0000398	biological_process	mRNA splicing, via spliceosome
C	0003713	molecular_function	transcription coactivator activity
C	0003714	molecular_function	transcription corepressor activity
C	0003723	molecular_function	RNA binding
C	0005112	molecular_function	Notch binding
C	0005515	molecular_function	protein binding
C	0005634	cellular_component	nucleus
C	0005654	cellular_component	nucleoplasm
C	0005681	cellular_component	spliceosomal complex
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0006397	biological_process	mRNA processing
C	0008024	cellular_component	cyclin/CDK positive transcription elongation factor complex
C	0008380	biological_process	RNA splicing
C	0016363	cellular_component	nuclear matrix
C	0016604	cellular_component	nuclear body
C	0016607	cellular_component	nuclear speck
C	0016922	molecular_function	nuclear receptor binding
C	0019899	molecular_function	enzyme binding
C	0030511	biological_process	positive regulation of transforming growth factor beta receptor signaling pathway
C	0042771	biological_process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
C	0042809	molecular_function	nuclear vitamin D receptor binding
C	0042974	molecular_function	nuclear retinoic acid receptor binding
C	0043923	biological_process	positive regulation by host of viral transcription
C	0045892	biological_process	negative regulation of DNA-templated transcription
C	0045944	biological_process	positive regulation of transcription by RNA polymerase II
C	0046332	molecular_function	SMAD binding
C	0048026	biological_process	positive regulation of mRNA splicing, via spliceosome
C	0048384	biological_process	retinoic acid receptor signaling pathway
C	0048385	biological_process	regulation of retinoic acid receptor signaling pathway
C	0050681	molecular_function	nuclear androgen receptor binding
C	0050769	biological_process	positive regulation of neurogenesis
C	0070562	biological_process	regulation of vitamin D receptor signaling pathway
C	0070564	biological_process	positive regulation of vitamin D receptor signaling pathway
C	0071007	cellular_component	U2-type catalytic step 2 spliceosome
C	0071013	cellular_component	catalytic step 2 spliceosome
C	0071300	biological_process	cellular response to retinoic acid
D	0000398	biological_process	mRNA splicing, via spliceosome
D	0000974	cellular_component	Prp19 complex
D	0001650	cellular_component	fibrillar center
D	0005515	molecular_function	protein binding
D	0005634	cellular_component	nucleus
D	0005654	cellular_component	nucleoplasm
D	0005662	cellular_component	DNA replication factor A complex
D	0005681	cellular_component	spliceosomal complex
D	0006397	biological_process	mRNA processing
D	0008380	biological_process	RNA splicing
D	0016607	cellular_component	nuclear speck
D	0031965	cellular_component	nuclear membrane
D	0034504	biological_process	protein localization to nucleus
D	0071007	cellular_component	U2-type catalytic step 2 spliceosome
D	0071013	cellular_component	catalytic step 2 spliceosome
D	1900087	biological_process	positive regulation of G1/S transition of mitotic cell cycle
E	0000398	biological_process	mRNA splicing, via spliceosome
E	0003723	molecular_function	RNA binding
E	0003729	molecular_function	mRNA binding
E	0005515	molecular_function	protein binding
E	0005634	cellular_component	nucleus
E	0005654	cellular_component	nucleoplasm
E	0005681	cellular_component	spliceosomal complex
E	0006397	biological_process	mRNA processing
E	0008380	biological_process	RNA splicing
E	0016607	cellular_component	nuclear speck
E	0071007	cellular_component	U2-type catalytic step 2 spliceosome
E	0071013	cellular_component	catalytic step 2 spliceosome
E	1990403	biological_process	embryonic brain development
L	0000077	biological_process	DNA damage checkpoint signaling
L	0000398	biological_process	mRNA splicing, via spliceosome
L	0000974	cellular_component	Prp19 complex
L	0000977	molecular_function	RNA polymerase II transcription regulatory region sequence-specific DNA binding
L	0000981	molecular_function	DNA-binding transcription factor activity, RNA polymerase II-specific
L	0001228	molecular_function	DNA-binding transcription activator activity, RNA polymerase II-specific
L	0003677	molecular_function	DNA binding
L	0003723	molecular_function	RNA binding
L	0005515	molecular_function	protein binding
L	0005634	cellular_component	nucleus
L	0005654	cellular_component	nucleoplasm
L	0005662	cellular_component	DNA replication factor A complex
L	0005681	cellular_component	spliceosomal complex
L	0005737	cellular_component	cytoplasm
L	0006281	biological_process	DNA repair
L	0006357	biological_process	regulation of transcription by RNA polymerase II
L	0006397	biological_process	mRNA processing
L	0008380	biological_process	RNA splicing
L	0016020	cellular_component	membrane
L	0016607	cellular_component	nuclear speck
L	0042802	molecular_function	identical protein binding
L	0045944	biological_process	positive regulation of transcription by RNA polymerase II
L	0071007	cellular_component	U2-type catalytic step 2 spliceosome
L	0071013	cellular_component	catalytic step 2 spliceosome
L	0071987	molecular_function	WD40-repeat domain binding
O	0000245	biological_process	spliceosomal complex assembly
O	0000398	biological_process	mRNA splicing, via spliceosome
O	0000974	cellular_component	Prp19 complex
O	0003723	molecular_function	RNA binding
O	0005515	molecular_function	protein binding
O	0005634	cellular_component	nucleus
O	0005654	cellular_component	nucleoplasm
O	0005681	cellular_component	spliceosomal complex
O	0006396	biological_process	RNA processing
O	0006397	biological_process	mRNA processing
O	0008380	biological_process	RNA splicing
O	0016607	cellular_component	nuclear speck
O	0071007	cellular_component	U2-type catalytic step 2 spliceosome
O	0071013	cellular_component	catalytic step 2 spliceosome
O	0071014	cellular_component	post-mRNA release spliceosomal complex
P	0000398	biological_process	mRNA splicing, via spliceosome
P	0000974	cellular_component	Prp19 complex
P	0003676	molecular_function	nucleic acid binding
P	0003723	molecular_function	RNA binding
P	0005515	molecular_function	protein binding
P	0005634	cellular_component	nucleus
P	0005654	cellular_component	nucleoplasm
P	0005681	cellular_component	spliceosomal complex
P	0005737	cellular_component	cytoplasm
P	0006397	biological_process	mRNA processing
P	0008380	biological_process	RNA splicing
P	0017070	molecular_function	U6 snRNA binding
P	0033120	biological_process	positive regulation of RNA splicing
P	0036002	molecular_function	pre-mRNA binding
P	0042307	biological_process	positive regulation of protein import into nucleus
P	0045292	biological_process	mRNA cis splicing, via spliceosome
P	0046827	biological_process	positive regulation of protein export from nucleus
P	0046872	molecular_function	metal ion binding
P	0048306	molecular_function	calcium-dependent protein binding
P	0071006	cellular_component	U2-type catalytic step 1 spliceosome
P	0071007	cellular_component	U2-type catalytic step 2 spliceosome
P	0071013	cellular_component	catalytic step 2 spliceosome
P	0071466	biological_process	cellular response to xenobiotic stimulus
Q	0000398	biological_process	mRNA splicing, via spliceosome
Q	0000785	cellular_component	chromatin
Q	0005515	molecular_function	protein binding
Q	0005634	cellular_component	nucleus
Q	0005654	cellular_component	nucleoplasm
Q	0005681	cellular_component	spliceosomal complex
Q	0006397	biological_process	mRNA processing
Q	0008380	biological_process	RNA splicing
Q	0016922	molecular_function	nuclear receptor binding
Q	0030374	molecular_function	nuclear receptor coactivator activity
Q	0045893	biological_process	positive regulation of DNA-templated transcription
Q	0071007	cellular_component	U2-type catalytic step 2 spliceosome
Q	2000825	biological_process	positive regulation of androgen receptor activity
R	0000398	biological_process	mRNA splicing, via spliceosome
R	0000974	cellular_component	Prp19 complex
R	0003723	molecular_function	RNA binding
R	0005515	molecular_function	protein binding
R	0005634	cellular_component	nucleus
R	0005654	cellular_component	nucleoplasm
R	0005681	cellular_component	spliceosomal complex
R	0005739	cellular_component	mitochondrion
R	0006397	biological_process	mRNA processing
R	0008380	biological_process	RNA splicing
R	0016607	cellular_component	nuclear speck
R	0045292	biological_process	mRNA cis splicing, via spliceosome
R	0071007	cellular_component	U2-type catalytic step 2 spliceosome
R	0071013	cellular_component	catalytic step 2 spliceosome
S	0000398	biological_process	mRNA splicing, via spliceosome
S	0003723	molecular_function	RNA binding
S	0003729	molecular_function	mRNA binding
S	0005515	molecular_function	protein binding
S	0005634	cellular_component	nucleus
S	0005654	cellular_component	nucleoplasm
S	0005681	cellular_component	spliceosomal complex
S	0006397	biological_process	mRNA processing
S	0008380	biological_process	RNA splicing
S	0015030	cellular_component	Cajal body
S	0016607	cellular_component	nuclear speck
S	0070742	molecular_function	C2H2 zinc finger domain binding
S	0071005	cellular_component	U2-type precatalytic spliceosome
S	0071007	cellular_component	U2-type catalytic step 2 spliceosome
S	0071013	cellular_component	catalytic step 2 spliceosome
V	0000398	biological_process	mRNA splicing, via spliceosome
V	0000413	biological_process	protein peptidyl-prolyl isomerization
V	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
V	0003824	molecular_function	catalytic activity
V	0005515	molecular_function	protein binding
V	0005634	cellular_component	nucleus
V	0005654	cellular_component	nucleoplasm
V	0005681	cellular_component	spliceosomal complex
V	0006397	biological_process	mRNA processing
V	0006457	biological_process	protein folding
V	0008380	biological_process	RNA splicing
V	0071007	cellular_component	U2-type catalytic step 2 spliceosome
V	0071013	cellular_component	catalytic step 2 spliceosome
V	0097718	molecular_function	disordered domain specific binding
V	1990403	biological_process	embryonic brain development
Y	0000375	biological_process	RNA splicing, via transesterification reactions
Y	0000398	biological_process	mRNA splicing, via spliceosome
Y	0003677	molecular_function	DNA binding
Y	0003723	molecular_function	RNA binding
Y	0005515	molecular_function	protein binding
Y	0005634	cellular_component	nucleus
Y	0005654	cellular_component	nucleoplasm
Y	0005681	cellular_component	spliceosomal complex
Y	0005829	cellular_component	cytosol
Y	0006397	biological_process	mRNA processing
Y	0008380	biological_process	RNA splicing
Y	0016363	cellular_component	nuclear matrix
Y	0016607	cellular_component	nuclear speck
Y	0048024	biological_process	regulation of mRNA splicing, via spliceosome
Y	0071013	cellular_component	catalytic step 2 spliceosome
s	0000398	biological_process	mRNA splicing, via spliceosome
s	0000413	biological_process	protein peptidyl-prolyl isomerization
s	0003755	molecular_function	peptidyl-prolyl cis-trans isomerase activity
s	0005634	cellular_component	nucleus
s	0005654	cellular_component	nucleoplasm
s	0006457	biological_process	protein folding
s	0071005	cellular_component	U2-type precatalytic spliceosome
s	0071013	cellular_component	catalytic step 2 spliceosome
t	0000398	biological_process	mRNA splicing, via spliceosome
t	0005515	molecular_function	protein binding
t	0005634	cellular_component	nucleus
t	0005654	cellular_component	nucleoplasm
t	0005681	cellular_component	spliceosomal complex
t	0005684	cellular_component	U2-type spliceosomal complex
t	0006281	biological_process	DNA repair
t	0006397	biological_process	mRNA processing
t	0008380	biological_process	RNA splicing
t	0016567	biological_process	protein ubiquitination
t	0016607	cellular_component	nuclear speck
t	0016740	molecular_function	transferase activity
t	0034247	biological_process	snoRNA splicing
t	0046872	molecular_function	metal ion binding
t	0061630	molecular_function	ubiquitin protein ligase activity
t	0070100	biological_process	negative regulation of chemokine-mediated signaling pathway
t	0071005	cellular_component	U2-type precatalytic spliceosome
u	0000245	biological_process	spliceosomal complex assembly
u	0000375	biological_process	RNA splicing, via transesterification reactions
u	0000398	biological_process	mRNA splicing, via spliceosome
u	0003723	molecular_function	RNA binding
u	0003729	molecular_function	mRNA binding
u	0005515	molecular_function	protein binding
u	0005634	cellular_component	nucleus
u	0005654	cellular_component	nucleoplasm
u	0005681	cellular_component	spliceosomal complex
u	0005684	cellular_component	U2-type spliceosomal complex
u	0005686	cellular_component	U2 snRNP
u	0005689	cellular_component	U12-type spliceosomal complex
u	0005730	cellular_component	nucleolus
u	0006338	biological_process	chromatin remodeling
u	0006397	biological_process	mRNA processing
u	0008380	biological_process	RNA splicing
u	0016607	cellular_component	nuclear speck
u	0034693	cellular_component	U11/U12 snRNP
u	0045943	biological_process	positive regulation of transcription by RNA polymerase I
u	0045944	biological_process	positive regulation of transcription by RNA polymerase II
u	0045945	biological_process	positive regulation of transcription by RNA polymerase III
u	0071004	cellular_component	U2-type prespliceosome
u	0071005	cellular_component	U2-type precatalytic spliceosome
u	0071013	cellular_component	catalytic step 2 spliceosome
u	0110016	cellular_component	B-WICH complex
u	1903241	biological_process	U2-type prespliceosome assembly
u	1990935	molecular_function	splicing factor binding
v	0000124	cellular_component	SAGA complex
v	0000375	biological_process	RNA splicing, via transesterification reactions
v	0000398	biological_process	mRNA splicing, via spliceosome
v	0003676	molecular_function	nucleic acid binding
v	0005515	molecular_function	protein binding
v	0005634	cellular_component	nucleus
v	0005654	cellular_component	nucleoplasm
v	0005681	cellular_component	spliceosomal complex
v	0005684	cellular_component	U2-type spliceosomal complex
v	0005686	cellular_component	U2 snRNP
v	0005689	cellular_component	U12-type spliceosomal complex
v	0005730	cellular_component	nucleolus
v	0006282	biological_process	regulation of DNA repair
v	0006397	biological_process	mRNA processing
v	0008380	biological_process	RNA splicing
v	0030620	molecular_function	U2 snRNA binding
v	0042177	biological_process	negative regulation of protein catabolic process
v	0043484	biological_process	regulation of RNA splicing
v	0044877	molecular_function	protein-containing complex binding
v	0045893	biological_process	positive regulation of DNA-templated transcription
v	0071005	cellular_component	U2-type precatalytic spliceosome
v	0071013	cellular_component	catalytic step 2 spliceosome
v	1903241	biological_process	U2-type prespliceosome assembly
x	0000124	cellular_component	SAGA complex
x	0000398	biological_process	mRNA splicing, via spliceosome
x	0003723	molecular_function	RNA binding
x	0005515	molecular_function	protein binding
x	0005634	cellular_component	nucleus
x	0005654	cellular_component	nucleoplasm
x	0005681	cellular_component	spliceosomal complex
x	0005684	cellular_component	U2-type spliceosomal complex
x	0005686	cellular_component	U2 snRNP
x	0005689	cellular_component	U12-type spliceosomal complex
x	0006282	biological_process	regulation of DNA repair
x	0006397	biological_process	mRNA processing
x	0008380	biological_process	RNA splicing
x	0043484	biological_process	regulation of RNA splicing
x	0045893	biological_process	positive regulation of DNA-templated transcription
x	0071005	cellular_component	U2-type precatalytic spliceosome
x	0071011	cellular_component	precatalytic spliceosome
x	1903241	biological_process	U2-type prespliceosome assembly
x	1990935	molecular_function	splicing factor binding
y	0000398	biological_process	mRNA splicing, via spliceosome
y	0003677	molecular_function	DNA binding
y	0003723	molecular_function	RNA binding
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005654	cellular_component	nucleoplasm
y	0005681	cellular_component	spliceosomal complex
y	0005684	cellular_component	U2-type spliceosomal complex
y	0005686	cellular_component	U2 snRNP
y	0005689	cellular_component	U12-type spliceosomal complex
y	0006397	biological_process	mRNA processing
y	0008270	molecular_function	zinc ion binding
y	0008380	biological_process	RNA splicing
y	0016363	cellular_component	nuclear matrix
y	0016607	cellular_component	nuclear speck
y	0045893	biological_process	positive regulation of DNA-templated transcription
y	0046872	molecular_function	metal ion binding
y	0048863	biological_process	stem cell differentiation
y	0071005	cellular_component	U2-type precatalytic spliceosome
y	0071011	cellular_component	precatalytic spliceosome
y	1903241	biological_process	U2-type prespliceosome assembly
z	0000398	biological_process	mRNA splicing, via spliceosome
z	0001825	biological_process	blastocyst formation
z	0003676	molecular_function	nucleic acid binding
z	0003723	molecular_function	RNA binding
z	0003729	molecular_function	mRNA binding
z	0005515	molecular_function	protein binding
z	0005634	cellular_component	nucleus
z	0005654	cellular_component	nucleoplasm
z	0005681	cellular_component	spliceosomal complex
z	0005684	cellular_component	U2-type spliceosomal complex
z	0005686	cellular_component	U2 snRNP
z	0005689	cellular_component	U12-type spliceosomal complex
z	0006397	biological_process	mRNA processing
z	0008380	biological_process	RNA splicing
z	0071011	cellular_component	precatalytic spliceosome
z	0071013	cellular_component	catalytic step 2 spliceosome
z	1903241	biological_process	U2-type prespliceosome assembly

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue MG 6 201

Chain	Residue
6	A53
6	G54
6	U74

site_id	AC2
Number of Residues	1
Details	binding site for residue MG 6 202

Chain	Residue
6	G75

site_id	AC3
Number of Residues	1
Details	binding site for residue MG 6 203

Chain	Residue
6	G75

site_id	AC4
Number of Residues	2
Details	binding site for residue MG 6 204

Chain	Residue
6	C55
6	G71

site_id	AC5
Number of Residues	9
Details	binding site for residue IHP A 3001

Chain	Residue
A	HIS584
A	LYS609
A	HIS610
A	TYR613
A	TYR614
A	LYS623
t	ARG179
A	ARG163
A	LYS442

site_id	AC6
Number of Residues	19
Details	binding site for residue GTP B 1500

Chain	Residue
B	LEU138
B	HIS139
B	HIS140
B	GLY141
B	LYS142
B	THR143
B	CYS144
B	ASP164
B	CYS166
B	ASP169
B	VAL179
B	GLY207
B	ASN258
B	LYS259
B	ASP261
B	ARG262
B	SER311
B	SER312
B	GLN313

site_id	AC7
Number of Residues	4
Details	binding site for residue ZN P 501

Chain	Residue
P	CYS24
P	CYS27
P	CYS81
P	CYS84

site_id	AC8
Number of Residues	3
Details	binding site for residue ZN P 502

Chain	Residue
P	CYS165
P	CYS173
P	CYS179

site_id	AC9
Number of Residues	5
Details	binding site for residue ZN P 503

Chain	Residue
P	CYS45
P	CYS48
P	CYS71
P	CYS74
P	GLN119

site_id	AD1
Number of Residues	3
Details	binding site for residue ZN Q 201

Chain	Residue
Q	CYS101
Q	CYS102
Q	CYS137

site_id	AD2
Number of Residues	4
Details	binding site for residue ZN Q 202

Chain	Residue
Q	LEU100
Q	CYS101
Q	CYS119
Q	ARG140

site_id	AD3
Number of Residues	4
Details	binding site for residue ZN Q 203

Chain	Residue
Q	CYS105
Q	CYS117
Q	CYS119
Q	CYS134

site_id	AD4
Number of Residues	4
Details	binding site for residue ZN t 401

Chain	Residue
t	CYS202
t	CYS211
t	CYS217
t	HIS221

site_id	AD5
Number of Residues	4
Details	binding site for residue ZN y 201

Chain	Residue
y	CYS11
y	CYS46
y	CYS49
y	CYS85

site_id	AD6
Number of Residues	4
Details	binding site for residue ZN y 202

Chain	Residue
y	CYS23
y	CYS26
y	CYS58
y	CYS61

site_id	AD7
Number of Residues	4
Details	binding site for residue ZN y 203

Chain	Residue
y	CYS30
y	CYS33
y	CYS72
y	CYS75

Functional Information from PROSITE/UniProt

site_id	PS00170
Number of Residues	18
Details	CSA_PPIASE_1 Cyclophilin-type peptidyl-prolyl cis-trans isomerase signature. YdnTiFHRVVpgFIvQGG

Chain	Residue	Details
s	TYR49-GLY66
V	TYR48-GLY65

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. FVCSATH

Chain	Residue	Details
v	PHE287-HIS293

site_id	PS00518
Number of Residues	10
Details	ZF_RING_1 Zinc finger RING-type signature. CrHyFCesCA

Chain	Residue	Details
t	CYS277-ALA286

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSCsmDcKIKLWEV

Chain	Residue	Details
E	LEU304-VAL318
D	LEU303-VAL317
D	ILE345-LEU359

site_id	PS00997
Number of Residues	23
Details	G10_1 G10 protein signature 1. LCClRCiqtrDtNfgtnCiCRVP

Chain	Residue	Details
Q	LEU100-PRO122

site_id	PS00998
Number of Residues	10
Details	G10_2 G10 protein signature 2. CtHCGCRGCS

Chain	Residue	Details
Q	CYS134-SER143

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
z	LYS29
y	CYS72
y	CYS75
y	CYS85
y	CYS23
y	CYS26
y	CYS30
y	CYS33
y	CYS46
y	CYS49
y	CYS58
y	CYS61

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
z	LYS41
v	LYS1171
D	SER391
C	SER446
C	SER479
C	SER481

site_id	SWS_FT_FI3
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
z	LYS29
u	CYS677
u	GLU1205

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: N-acetylalanine => ECO:0000250\|UniProtKB:P83870

Chain	Residue	Details
y	ALA2
u	THR235
u	THR426

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0007744\|PubMed:19608861

Chain	Residue	Details
y	LYS3
S	SER1460
S	SER1462
S	SER1482
S	SER1483
S	SER1501
S	SER1621
S	SER1893
S	SER2343
S	SER2394
S	SER2453
S	SER222
S	SER454
S	SER484
S	SER486
S	SER875
S	SER1336
S	SER1368
S	SER1421

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
y	SER94
C	LYS416
C	LYS441
C	LYS452
u	LYS554
u	LYS562
C	LYS141
C	LYS158
C	LYS258
C	LYS286
C	LYS339
C	LYS344

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17924679, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR142
Y	SER797
Y	SER802

site_id	SWS_FT_FI8
Number of Residues	1
Details	MOD_RES: Citrulline => ECO:0000250

Chain	Residue	Details
u	ARG157
S	SER1179
S	SER2581

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	SER194
S	SER1083
S	SER1152

site_id	SWS_FT_FI10
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:20068231

Chain	Residue	Details
u	THR203
S	SER857
S	SER952
S	SER1318
S	SER1401
S	SER2100

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR207
3	SER240
3	SER248

site_id	SWS_FT_FI12
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR211
S	SER353
8	LYS280
8	LYS492
8	LYS543
8	LYS770
8	LYS790
8	LYS843
8	LYS857

site_id	SWS_FT_FI13
Number of Residues	1
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250\|UniProtKB:Q99NB9

Chain	Residue	Details
u	LYS214
S	SER358
S	SER846
S	SER1214

site_id	SWS_FT_FI14
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:17924679, ECO:0007744\|PubMed:18220336, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR223
S	THR1106
S	THR2381

site_id	SWS_FT_FI15
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR227
Y	SER420
Y	SER583
Y	SER707
Y	SER795

site_id	SWS_FT_FI16
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:Q99NB9

Chain	Residue	Details
u	SER229
Y	THR555
Y	THR572
Y	THR574
Y	THR581
Y	THR793

site_id	SWS_FT_FI17
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000269\|PubMed:12105215

Chain	Residue	Details
u	THR244
Y	SER431
Y	SER605
Y	SER607

site_id	SWS_FT_FI18
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000305\|PubMed:12105215

Chain	Residue	Details
u	THR248
Y	SER777

site_id	SWS_FT_FI19
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR257
u	THR261
u	THR278
u	THR303
u	THR313

site_id	SWS_FT_FI20
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18220336, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR267

site_id	SWS_FT_FI21
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	THR273
Y	SER465

site_id	SWS_FT_FI22
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	SER287
S	SER1124
S	SER2702

site_id	SWS_FT_FI23
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR296
S	SER2121
S	SER2675
S	SER2677
Y	SER526
Y	SER528
Y	SER530
Y	SER532
Y	SER773
Y	SER901
S	SER1541
S	SER1876

site_id	SWS_FT_FI24
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983

Chain	Residue	Details
u	THR299
S	SER704
S	SER706
S	SER992
S	SER1198
S	SER1227
S	SER1254
S	SER1257
S	SER1258
S	SER2018
S	SER2030
Y	SER551
S	SER2042
S	SER2310
S	SER2368
S	SER2376
S	SER2740
Y	SER705
S	SER508
S	SER510
S	SER534
S	SER536
S	SER543
S	SER702

site_id	SWS_FT_FI25
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	SER322
Y	SER562

site_id	SWS_FT_FI26
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR326
S	SER2123
S	SER2398
S	SER2407
S	SER2692

site_id	SWS_FT_FI27
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
u	THR328
S	SER1522
S	SER1970

site_id	SWS_FT_FI28
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	SER332
S	SER1423
S	SER1616
S	SER1620
S	SER1024
S	SER1042
S	SER1266
S	SER1270
S	SER1271
S	SER1348
S	SER1383
S	SER1384

site_id	SWS_FT_FI29
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
u	THR341

site_id	SWS_FT_FI30
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692

Chain	Residue	Details
u	SER344
Y	SER628

site_id	SWS_FT_FI31
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
u	SER349

site_id	SWS_FT_FI32
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR350
u	THR436

site_id	SWS_FT_FI33
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18691976, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR354
S	SER1582
S	SER1598
S	SER1600
S	SER1601
S	SER1658
S	SER1727
S	SER1729
S	SER1731
S	SER1732
S	SER1818
Y	SER715
S	SER1822
S	SER1884
S	SER2090
S	SER2415
S	SER2429
Y	SER748
S	SER1517
S	SER1519
S	SER1521
S	SER1577
S	SER1579
S	SER1581

site_id	SWS_FT_FI34
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	SER400

site_id	SWS_FT_FI35
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by DYRK1A => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
u	THR434

site_id	SWS_FT_FI36
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
u	SER488
S	SER1946
S	SER1958
S	SER2118
S	SER968
S	SER970
S	SER972
S	SER1032
S	SER1451
S	SER1691
S	SER1693
S	SER1923

site_id	SWS_FT_FI37
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
u	LYS214
S	SER1975
S	SER1984
S	SER1987
S	SER1996
S	SER1999
S	SER2008
S	SER2011
S	SER2664
S	SER2706
S	SER1497
S	SER1502
S	SER1762
S	SER1764
S	SER1890
S	SER1916
S	SER1919
S	SER1972

site_id	SWS_FT_FI38
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	SER738
u	LYS430
S	SER1925
S	SER1948
S	SER1960

site_id	SWS_FT_FI39
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:25114211, ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
u	LYS413
S	THR1043
S	THR1931
S	THR1954
S	THR1966
S	THR1978
S	THR2092

site_id	SWS_FT_FI40
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER752

site_id	SWS_FT_FI41
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER754
Y	SER756

site_id	SWS_FT_FI42
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER769

site_id	SWS_FT_FI43
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER775

site_id	SWS_FT_FI44
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:Q52KI8

Chain	Residue	Details
Y	THR778
S	SER2690

site_id	SWS_FT_FI45
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER781
S	SER1444
S	SER1542
S	SER1552
S	SER1694
S	SER1878
S	SER2412

site_id	SWS_FT_FI46
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	SER791
S	SER1073

site_id	SWS_FT_FI47
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
Y	THR872
S	SER1101

site_id	SWS_FT_FI48
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18318008, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
Y	SER874

site_id	SWS_FT_FI49
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS127
S	SER1404
Y	LYS447
Y	LYS459
Y	LYS472
Y	LYS869

site_id	SWS_FT_FI50
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2); alternate => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS231
S	SER1857
S	SER2335

site_id	SWS_FT_FI51
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:25218447, ECO:0007744\|PubMed:25755297, ECO:0007744\|PubMed:28112733

Chain	Residue	Details
Y	LYS249

site_id	SWS_FT_FI52
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR1208
S	THR1880

site_id	SWS_FT_FI53
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER1219

site_id	SWS_FT_FI54
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER1320
S	SER1387

site_id	SWS_FT_FI55
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER1326

site_id	SWS_FT_FI56
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER1329

site_id	SWS_FT_FI57
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER1382

site_id	SWS_FT_FI58
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER1403

site_id	SWS_FT_FI59
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR1413

site_id	SWS_FT_FI60
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR1434

site_id	SWS_FT_FI61
Number of Residues	5
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648

Chain	Residue	Details
S	THR1453
S	THR1472
S	THR1511
S	THR1698
S	THR2144

site_id	SWS_FT_FI62
Number of Residues	5
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER1458
S	SER1648
S	SER2020
S	SER2032
S	SER2067

site_id	SWS_FT_FI63
Number of Residues	9
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER1463
S	SER1499
S	SER1854
S	SER2044
S	SER2046
S	SER2071
S	SER2426
S	SER2684
S	SER2688

site_id	SWS_FT_FI64
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17081983, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR1492

site_id	SWS_FT_FI65
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:17924679, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR1531

site_id	SWS_FT_FI66
Number of Residues	3
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692

Chain	Residue	Details
S	THR1927
S	THR1950
S	THR1962

site_id	SWS_FT_FI67
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2022
S	THR2034

site_id	SWS_FT_FI68
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2069

site_id	SWS_FT_FI69
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER2102

site_id	SWS_FT_FI70
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2104

site_id	SWS_FT_FI71
Number of Residues	7
Details	MOD_RES: Omega-N-methylarginine => ECO:0007744\|PubMed:24129315

Chain	Residue	Details
S	ARG2194
S	ARG2207
S	ARG2231
S	ARG2246
S	ARG2274
S	ARG2288
S	ARG2342

site_id	SWS_FT_FI72
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18220336, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER2272

site_id	SWS_FT_FI73
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2289

site_id	SWS_FT_FI74
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243

Chain	Residue	Details
S	THR2291

site_id	SWS_FT_FI75
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231

Chain	Residue	Details
S	THR2302

site_id	SWS_FT_FI76
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2316

site_id	SWS_FT_FI77
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2329
S	THR2409

site_id	SWS_FT_FI78
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	SER2382

site_id	SWS_FT_FI79
Number of Residues	1
Details	MOD_RES: Omega-N-methylarginine; alternate => ECO:0007744\|PubMed:24129315

Chain	Residue	Details
S	ARG2384

site_id	SWS_FT_FI80
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:17525332, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:19690332, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER2449

site_id	SWS_FT_FI81
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:24275569

Chain	Residue	Details
S	THR2583

site_id	SWS_FT_FI82
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	THR2599
S	THR2738

site_id	SWS_FT_FI83
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744\|PubMed:16964243, ECO:0007744\|PubMed:18669648, ECO:0007744\|PubMed:20068231, ECO:0007744\|PubMed:21406692, ECO:0007744\|PubMed:23186163

Chain	Residue	Details
S	SER2694

site_id	SWS_FT_FI84
Number of Residues	4
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744\|PubMed:28112733

Chain	Residue	Details
S	LYS108
S	LYS130
S	LYS2587

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)