6ERG
Complex of XLF and heterodimer Ku bound to DNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000723 | biological_process | telomere maintenance |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003678 | molecular_function | DNA helicase activity |
| A | 0003684 | molecular_function | damaged DNA binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0006303 | biological_process | double-strand break repair via nonhomologous end joining |
| A | 0042162 | molecular_function | telomeric DNA binding |
| A | 0043564 | cellular_component | Ku70:Ku80 complex |
| B | 0000723 | biological_process | telomere maintenance |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003678 | molecular_function | DNA helicase activity |
| B | 0003684 | molecular_function | damaged DNA binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0006303 | biological_process | double-strand break repair via nonhomologous end joining |
| B | 0006310 | biological_process | DNA recombination |
| B | 0042162 | molecular_function | telomeric DNA binding |
| B | 0043564 | cellular_component | Ku70:Ku80 complex |
| D | 0000723 | biological_process | telomere maintenance |
| D | 0003677 | molecular_function | DNA binding |
| D | 0003678 | molecular_function | DNA helicase activity |
| D | 0003684 | molecular_function | damaged DNA binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0006303 | biological_process | double-strand break repair via nonhomologous end joining |
| D | 0042162 | molecular_function | telomeric DNA binding |
| D | 0043564 | cellular_component | Ku70:Ku80 complex |
| E | 0000723 | biological_process | telomere maintenance |
| E | 0003677 | molecular_function | DNA binding |
| E | 0003678 | molecular_function | DNA helicase activity |
| E | 0003684 | molecular_function | damaged DNA binding |
| E | 0005634 | cellular_component | nucleus |
| E | 0006303 | biological_process | double-strand break repair via nonhomologous end joining |
| E | 0006310 | biological_process | DNA recombination |
| E | 0042162 | molecular_function | telomeric DNA binding |
| E | 0043564 | cellular_component | Ku70:Ku80 complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| C | SER287 | |
| F | SER287 | |
| B | LYS332 | |
| E | LYS144 | |
| E | LYS265 | |
| E | LYS332 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | SER255 | |
| B | SER258 | |
| B | SER318 | |
| E | SER255 | |
| E | SER258 | |
| E | SER318 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| B | THR535 | |
| E | THR535 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| B | LYS195 | |
| A | LYS331 | |
| B | LYS532 | |
| B | LYS534 | |
| E | LYS195 | |
| D | LYS331 | |
| E | LYS532 | |
| E | LYS534 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by PRKDC => ECO:0000269|PubMed:9362500 |
| Chain | Residue | Details |
| A | SER51 | |
| D | SER51 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | THR455 | |
| D | THR455 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER477 | |
| D | SER477 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER520 | |
| D | SER520 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS287 | |
| A | LYS317 | |
| D | LYS287 | |
| D | LYS317 |
