Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004222 | molecular_function | metalloendopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| A | 0008237 | molecular_function | metallopeptidase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0031012 | cellular_component | extracellular matrix |
| B | 0004222 | molecular_function | metalloendopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| B | 0008237 | molecular_function | metallopeptidase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0031012 | cellular_component | extracellular matrix |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue LPW A 301 |
| Chain | Residue |
| A | GLY179 |
| A | HIS228 |
| A | VAL235 |
| A | PHE237 |
| A | PRO238 |
| A | THR239 |
| A | TYR240 |
| A | ZN302 |
| A | HOH517 |
| B | SER230 |
| B | PRO232 |
| A | ILE180 |
| A | LEU181 |
| A | ALA182 |
| A | LEU214 |
| A | THR215 |
| A | HIS218 |
| A | GLU219 |
| A | HIS222 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 302 |
| Chain | Residue |
| A | HIS218 |
| A | HIS222 |
| A | HIS228 |
| A | LPW301 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 303 |
| Chain | Residue |
| A | HIS168 |
| A | ASP170 |
| A | HIS183 |
| A | HIS196 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 304 |
| Chain | Residue |
| A | ASP158 |
| A | GLY190 |
| A | GLY192 |
| A | ASP194 |
| A | HOH401 |
| A | HOH413 |
| A | HOH484 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | ASP124 |
| A | GLU199 |
| A | GLU201 |
| A | HOH527 |
| A | HOH531 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 306 |
| Chain | Residue |
| A | ASP175 |
| A | GLY176 |
| A | GLY178 |
| A | ILE180 |
| A | ASP198 |
| A | GLU201 |
| site_id | AC7 |
| Number of Residues | 18 |
| Details | binding site for residue LPW B 301 |
| Chain | Residue |
| A | SER230 |
| B | GLY179 |
| B | ILE180 |
| B | LEU181 |
| B | ALA182 |
| B | LEU214 |
| B | HIS218 |
| B | GLU219 |
| B | HIS222 |
| B | HIS228 |
| B | VAL235 |
| B | PHE237 |
| B | PRO238 |
| B | THR239 |
| B | TYR240 |
| B | ZN302 |
| B | HOH505 |
| B | HOH515 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 302 |
| Chain | Residue |
| B | HIS218 |
| B | HIS222 |
| B | HIS228 |
| B | LPW301 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 303 |
| Chain | Residue |
| B | HIS168 |
| B | ASP170 |
| B | HIS183 |
| B | HIS196 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 304 |
| Chain | Residue |
| B | ASP158 |
| B | GLY190 |
| B | GLY192 |
| B | ASP194 |
| B | HOH418 |
| B | HOH447 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue CA B 305 |
| Chain | Residue |
| B | ASP124 |
| B | GLU199 |
| B | GLU201 |
| B | HOH509 |
| B | HOH545 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 306 |
| Chain | Residue |
| B | ASP175 |
| B | GLY176 |
| B | GLY178 |
| B | ILE180 |
| B | ASP198 |
| B | GLU201 |
Functional Information from PROSITE/UniProt
| site_id | PS00142 |
| Number of Residues | 10 |
| Details | ZINC_PROTEASE Neutral zinc metallopeptidases, zinc-binding region signature. TAVHEIGHSL |
| Chain | Residue | Details |
| A | THR215-LEU224 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: |
| Chain | Residue | Details |
| A | GLU219 | |
| B | GLU219 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 38 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASP175 | |
| A | GLY176 | |
| A | GLY178 | |
| A | ILE180 | |
| A | HIS183 | |
| A | GLY190 | |
| A | GLY192 | |
| A | ASP194 | |
| A | HIS196 | |
| A | ASP198 | |
| A | GLU199 | |
| A | GLU201 | |
| A | HIS218 | |
| A | HIS222 | |
| A | HIS228 | |
| B | ASP124 | |
| B | ASP158 | |
| B | HIS168 | |
| B | ASP170 | |
| B | ASP175 | |
| B | GLY176 | |
| B | GLY178 | |
| B | ILE180 | |
| B | HIS183 | |
| B | GLY190 | |
| B | GLY192 | |
| B | ASP194 | |
| B | HIS196 | |
| B | ASP198 | |
| B | GLU199 | |
| B | GLU201 | |
| B | HIS218 | |
| B | HIS222 | |
| B | HIS228 | |
| A | ASP124 | |
| A | ASP158 | |
| A | HIS168 | |
| A | ASP170 | |
