6EJX

The metal ion-dependent adhesion site (MIDAS) of the alphaMbeta2 integrin Mac-1 I-domain promiscuously and competitively binds multiple ligands in the regulation of Leukocyte function

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue IMD D 301

Chain	Residue
D	ALA256
D	PRO257
D	SER260
D	TYR261
D	PRO262

---

site_id	AC2
Number of Residues	7
Details	binding site for residue PEG D 302

Chain	Residue
D	HOH425
D	HOH507
D	HOH567
D	ASN83
D	GLU130
D	TYR132
D	MES303

---

site_id	AC3
Number of Residues	6
Details	binding site for residue MES D 303

Chain	Residue
D	TYR63
D	ASP65
D	ASP85
D	PEG302
D	HOH402
D	HOH408

---

site_id	AC4
Number of Residues	5
Details	binding site for residue IMD A 301

Chain	Residue
A	ALA256
A	PRO257
A	SER260
A	TYR261
A	PRO262

---

site_id	AC5
Number of Residues	10
Details	binding site for residue PEG A 302

Chain	Residue
A	ASP108
A	SER110
A	PHE111
A	TYR132
A	GLN134
A	ASN156
A	GOL304
A	HOH410
A	HOH496
A	HOH580

---

site_id	AC6
Number of Residues	2
Details	binding site for residue PEG A 303

Chain	Residue
A	PRO262
A	LYS264

---

site_id	AC7
Number of Residues	6
Details	binding site for residue GOL A 304

Chain	Residue
A	ASP108
A	GLU130
A	TYR132
A	PEG302
A	POL309
A	HOH492

---

site_id	AC8
Number of Residues	2
Details	binding site for residue GOL A 305

Chain	Residue
A	ARG163
A	TRP185

---

site_id	AC9
Number of Residues	5
Details	binding site for residue POL A 306

Chain	Residue
A	ARG219
A	GLN223
A	SER260
A	TYR261
A	PRO262

---

site_id	AD1
Number of Residues	1
Details	binding site for residue POL A 307

Chain	Residue
A	PRO267

---

site_id	AD2
Number of Residues	2
Details	binding site for residue POL A 308

Chain	Residue
A	HIS55
A	HOH508

---

site_id	AD3
Number of Residues	3
Details	binding site for residue POL A 309

Chain	Residue
A	ASN83
A	GOL304
A	MES310

---

site_id	AD4
Number of Residues	4
Details	binding site for residue MES A 310

Chain	Residue
A	TYR63
A	ASP85
A	POL309
A	HOH402

---