Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004675 | molecular_function | transmembrane receptor protein serine/threonine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007178 | biological_process | cell surface receptor protein serine/threonine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue A3F A 601 |
| Chain | Residue |
| A | ALA233 |
| A | ASP293 |
| A | LYS340 |
| A | ASN341 |
| A | LEU343 |
| A | EDO604 |
| A | EDO607 |
| A | HOH728 |
| A | LYS235 |
| A | LEU263 |
| A | LEU281 |
| A | THR283 |
| A | HIS284 |
| A | HIS286 |
| A | GLY289 |
| A | SER290 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 602 |
| Chain | Residue |
| A | THR209 |
| A | LEU210 |
| A | GLN480 |
| A | ASN481 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | PHE431 |
| A | ASP433 |
| A | ARG454 |
| A | PRO455 |
| A | HOH721 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | ASP293 |
| A | LYS497 |
| A | ILE498 |
| A | SER501 |
| A | A3F601 |
| A | EDO607 |
| A | HOH702 |
| A | HOH707 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | ILE321 |
| A | LYS400 |
| A | THR487 |
| A | ALA488 |
| A | LEU489 |
| A | HOH717 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | GLN296 |
| A | ARG417 |
| A | ASP426 |
| A | TYR427 |
| A | LYS493 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | MET288 |
| A | ASP293 |
| A | LYS497 |
| A | A3F601 |
| A | EDO604 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | ARG335 |
| A | HOH713 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | GLN453 |
| A | ARG454 |
| A | ASN456 |
| A | ILE457 |
| A | ASN459 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | TYR292 |
| A | PRO429 |
| A | ASN437 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 22 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. VGKGRYGEVWrGswqgen............VAVK |
| Chain | Residue | Details |
| A | VAL214-LYS235 | |
| site_id | PS00108 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. IaHrDLKskNILV |
| Chain | Residue | Details |
| A | ILE332-VAL344 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 294 |
| Details | Domain: {"description":"Protein kinase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10027","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 9 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19369195","evidenceCode":"ECO:0007744"}]} |
