6DLD

Crystal structure of IgLON5/NEGR1 heterodimer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005576	cellular_component	extracellular region
A	0005886	cellular_component	plasma membrane
A	0007157	biological_process	heterophilic cell-cell adhesion
A	0008038	biological_process	neuron recognition
A	0051963	biological_process	regulation of synapse assembly
B	0005515	molecular_function	protein binding
B	0005576	cellular_component	extracellular region
B	0005770	cellular_component	late endosome
B	0005886	cellular_component	plasma membrane
B	0007155	biological_process	cell adhesion
B	0007157	biological_process	heterophilic cell-cell adhesion
B	0009306	biological_process	protein secretion
B	0014069	cellular_component	postsynaptic density
B	0030425	cellular_component	dendrite
B	0031647	biological_process	regulation of protein stability
B	0042632	biological_process	cholesterol homeostasis
B	0043025	cellular_component	neuronal cell body
B	0043197	cellular_component	dendritic spine
B	0043198	cellular_component	dendritic shaft
B	0044325	molecular_function	transmembrane transporter binding
B	0044860	biological_process	protein localization to plasma membrane raft
B	0051963	biological_process	regulation of synapse assembly
B	0051964	biological_process	negative regulation of synapse assembly
B	0060253	biological_process	negative regulation of glial cell proliferation
B	0097440	cellular_component	apical dendrite
B	0098552	cellular_component	side of membrane
C	0005576	cellular_component	extracellular region
C	0005886	cellular_component	plasma membrane
C	0007157	biological_process	heterophilic cell-cell adhesion
C	0008038	biological_process	neuron recognition
C	0051963	biological_process	regulation of synapse assembly
D	0005515	molecular_function	protein binding
D	0005576	cellular_component	extracellular region
D	0005770	cellular_component	late endosome
D	0005886	cellular_component	plasma membrane
D	0007155	biological_process	cell adhesion
D	0007157	biological_process	heterophilic cell-cell adhesion
D	0009306	biological_process	protein secretion
D	0014069	cellular_component	postsynaptic density
D	0030425	cellular_component	dendrite
D	0031647	biological_process	regulation of protein stability
D	0042632	biological_process	cholesterol homeostasis
D	0043025	cellular_component	neuronal cell body
D	0043197	cellular_component	dendritic spine
D	0043198	cellular_component	dendritic shaft
D	0044325	molecular_function	transmembrane transporter binding
D	0044860	biological_process	protein localization to plasma membrane raft
D	0051963	biological_process	regulation of synapse assembly
D	0051964	biological_process	negative regulation of synapse assembly
D	0060253	biological_process	negative regulation of glial cell proliferation
D	0097440	cellular_component	apical dendrite
D	0098552	cellular_component	side of membrane

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	334
Details	Domain: {"description":"Ig-like C2-type 2"}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	89
Details	Domain: {"description":"Ig-like C2-type 3"}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	22
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	2
Details	Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"Q80Z24","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	96
Details	Domain: {"description":"Ig-like C2-type 1"}

Chain

Residue

Details

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