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6DLD

Crystal structure of IgLON5/NEGR1 heterodimer

Functional Information from GO Data
ChainGOidnamespacecontents
A0005576cellular_componentextracellular region
A0008038biological_processneuron recognition
A0050885biological_processneuromuscular process controlling balance
A0061744biological_processmotor behavior
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005886cellular_componentplasma membrane
B0007155biological_processcell adhesion
B0007420biological_processbrain development
B0007626biological_processlocomotory behavior
B0007631biological_processfeeding behavior
B0010976biological_processpositive regulation of neuron projection development
B0014069cellular_componentpostsynaptic density
B0016020cellular_componentmembrane
B0030425cellular_componentdendrite
B0031175biological_processneuron projection development
B0035176biological_processsocial behavior
B0042632biological_processcholesterol homeostasis
B0043025cellular_componentneuronal cell body
B0043197cellular_componentdendritic spine
B0043198cellular_componentdendritic shaft
B0045444biological_processfat cell differentiation
B0046878biological_processpositive regulation of saliva secretion
B0048812biological_processneuron projection morphogenesis
B0050850biological_processpositive regulation of calcium-mediated signaling
B0051963biological_processregulation of synapse assembly
B0051964biological_processnegative regulation of synapse assembly
B0060253biological_processnegative regulation of glial cell proliferation
B0060538biological_processskeletal muscle organ development
B0097440cellular_componentapical dendrite
B0098552cellular_componentside of membrane
B0098609biological_processcell-cell adhesion
B0140042biological_processlipid droplet formation
C0005576cellular_componentextracellular region
C0008038biological_processneuron recognition
C0050885biological_processneuromuscular process controlling balance
C0061744biological_processmotor behavior
D0005515molecular_functionprotein binding
D0005576cellular_componentextracellular region
D0005886cellular_componentplasma membrane
D0007155biological_processcell adhesion
D0007420biological_processbrain development
D0007626biological_processlocomotory behavior
D0007631biological_processfeeding behavior
D0010976biological_processpositive regulation of neuron projection development
D0014069cellular_componentpostsynaptic density
D0016020cellular_componentmembrane
D0030425cellular_componentdendrite
D0031175biological_processneuron projection development
D0035176biological_processsocial behavior
D0042632biological_processcholesterol homeostasis
D0043025cellular_componentneuronal cell body
D0043197cellular_componentdendritic spine
D0043198cellular_componentdendritic shaft
D0045444biological_processfat cell differentiation
D0046878biological_processpositive regulation of saliva secretion
D0048812biological_processneuron projection morphogenesis
D0050850biological_processpositive regulation of calcium-mediated signaling
D0051963biological_processregulation of synapse assembly
D0051964biological_processnegative regulation of synapse assembly
D0060253biological_processnegative regulation of glial cell proliferation
D0060538biological_processskeletal muscle organ development
D0097440cellular_componentapical dendrite
D0098552cellular_componentside of membrane
D0098609biological_processcell-cell adhesion
D0140042biological_processlipid droplet formation
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:Q80Z24
ChainResidueDetails
BTYR187
CASN288
DTYR187
AASN67
AASN137
AASN288
CASN41
CASN49
CASN67
CASN137

site_idSWS_FT_FI2
Number of Residues2
DetailsLIPID: GPI-anchor amidated glycine => ECO:0000255
ChainResidueDetails
BGLY324
DGLY324

site_idSWS_FT_FI3
Number of Residues12
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
BASN73
DASN286
DASN294
DASN307
BASN155
BASN275
BASN286
BASN294
BASN307
DASN73
DASN155
DASN275

238268

PDB entries from 2025-07-02

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