6CVL

Crystal structure of the Escherichia coli ATPgS-bound MetNI methionine ABC transporter in complex with its MetQ binding protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005886	cellular_component	plasma membrane
A	0006865	biological_process	amino acid transport
A	0015191	molecular_function	L-methionine transmembrane transporter activity
A	0015821	biological_process	methionine transport
A	0016020	cellular_component	membrane
A	0033232	molecular_function	ABC-type D-methionine transporter activity
A	0048473	biological_process	D-methionine transmembrane transport
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	1902475	biological_process	L-alpha-amino acid transmembrane transport
A	1903692	biological_process	methionine import across plasma membrane
A	1990197	cellular_component	methionine-importing ABC transporter complex
B	0005515	molecular_function	protein binding
B	0005886	cellular_component	plasma membrane
B	0006865	biological_process	amino acid transport
B	0015191	molecular_function	L-methionine transmembrane transporter activity
B	0015821	biological_process	methionine transport
B	0016020	cellular_component	membrane
B	0033232	molecular_function	ABC-type D-methionine transporter activity
B	0048473	biological_process	D-methionine transmembrane transport
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	1902475	biological_process	L-alpha-amino acid transmembrane transport
B	1903692	biological_process	methionine import across plasma membrane
B	1990197	cellular_component	methionine-importing ABC transporter complex
C	0000166	molecular_function	nucleotide binding
C	0003824	molecular_function	catalytic activity
C	0005515	molecular_function	protein binding
C	0005524	molecular_function	ATP binding
C	0005886	cellular_component	plasma membrane
C	0006865	biological_process	amino acid transport
C	0009276	cellular_component	Gram-negative-bacterium-type cell wall
C	0015191	molecular_function	L-methionine transmembrane transporter activity
C	0016020	cellular_component	membrane
C	0016887	molecular_function	ATP hydrolysis activity
C	0033232	molecular_function	ABC-type D-methionine transporter activity
C	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
C	0048473	biological_process	D-methionine transmembrane transport
C	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
C	1902475	biological_process	L-alpha-amino acid transmembrane transport
C	1903692	biological_process	methionine import across plasma membrane
C	1990197	cellular_component	methionine-importing ABC transporter complex
D	0000166	molecular_function	nucleotide binding
D	0003824	molecular_function	catalytic activity
D	0005515	molecular_function	protein binding
D	0005524	molecular_function	ATP binding
D	0005886	cellular_component	plasma membrane
D	0006865	biological_process	amino acid transport
D	0009276	cellular_component	Gram-negative-bacterium-type cell wall
D	0015191	molecular_function	L-methionine transmembrane transporter activity
D	0016020	cellular_component	membrane
D	0016887	molecular_function	ATP hydrolysis activity
D	0033232	molecular_function	ABC-type D-methionine transporter activity
D	0042626	molecular_function	ATPase-coupled transmembrane transporter activity
D	0048473	biological_process	D-methionine transmembrane transport
D	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
D	1902475	biological_process	L-alpha-amino acid transmembrane transport
D	1903692	biological_process	methionine import across plasma membrane
D	1990197	cellular_component	methionine-importing ABC transporter complex
E	0005515	molecular_function	protein binding
E	0005886	cellular_component	plasma membrane
E	0006865	biological_process	amino acid transport
E	0015821	biological_process	methionine transport
E	0016020	cellular_component	membrane
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0048473	biological_process	D-methionine transmembrane transport
E	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
E	1903692	biological_process	methionine import across plasma membrane
E	1990197	cellular_component	methionine-importing ABC transporter complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue HG C 401

Chain	Residue
C	HIS0
D	CYS210

---

site_id	AC2
Number of Residues	2
Details	binding site for residue HG C 402

Chain	Residue
C	CYS164
C	LEU183

---

site_id	AC3
Number of Residues	18
Details	binding site for residue AGS C 403

Chain	Residue
C	GLY41
C	ALA42
C	GLY43
C	LYS44
C	SER45
C	THR46
C	HIS199
D	ASN140
D	LEU141
D	SER142
D	GLY143
D	GLY144
D	GLN145
C	PHE11
C	GLN13
C	ILE18
C	ALA20
C	SER40

---

site_id	AC4
Number of Residues	1
Details	binding site for residue HG D 401

Chain	Residue
D	IOD403

---

site_id	AC5
Number of Residues	2
Details	binding site for residue IOD D 402

Chain	Residue
D	THR168
D	THR198

---

site_id	AC6
Number of Residues	3
Details	binding site for residue IOD D 403

Chain	Residue
D	CYS164
D	LEU183
D	HG401

---

site_id	AC7
Number of Residues	17
Details	binding site for residue AGS D 404

Chain	Residue
C	ASN140
C	SER142
C	GLY143
C	GLY144
C	GLN145
C	ALA170
D	PHE11
D	GLN13
D	ILE18
D	SER40
D	GLY41
D	ALA42
D	GLY43
D	LYS44
D	SER45
D	THR46
D	HIS199

---

Functional Information from PROSITE/UniProt

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQKQRVAIARAL

Chain	Residue	Details
C	LEU141-LEU155

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	478
Details	Domain: {"description":"ABC transporter","evidences":[{"source":"HAMAP-Rule","id":"MF_01719","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	156
Details	Region: {"description":"C2 domain","evidences":[{"source":"PubMed","id":"18621668","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"22095702","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	62
Details	Topological domain: {"description":"Periplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	200
Details	Transmembrane: {"description":"Helical","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	130
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	382
Details	Domain: {"description":"ABC transmembrane type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00441","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---