Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003677 | molecular_function | DNA binding |
A | 0003916 | molecular_function | DNA topoisomerase activity |
A | 0003917 | molecular_function | DNA topoisomerase type I (single strand cut, ATP-independent) activity |
A | 0006265 | biological_process | DNA topological change |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue MG A 801 |
Chain | Residue |
A | GLU24 |
A | ASP111 |
A | HOH903 |
B | DC6 |
B | DT7 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue MG A 802 |
Chain | Residue |
A | GLU296 |
A | HIS492 |
A | HOH902 |
site_id | AC3 |
Number of Residues | 3 |
Details | binding site for residue MG A 803 |
Chain | Residue |
A | ASP507 |
A | HIS509 |
A | ASP220 |
site_id | AC4 |
Number of Residues | 3 |
Details | binding site for residue MG A 804 |
Chain | Residue |
A | GLU589 |
A | GLU598 |
A | HIS613 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue PO4 A 805 |
Chain | Residue |
A | GLY112 |
A | HIS139 |
A | GLN386 |
A | HIS389 |
Functional Information from PROSITE/UniProt
site_id | PS00396 |
Number of Residues | 15 |
Details | TOPO_IA_1 Topoisomerase (Topo) IA-type active site signature. QrLYEngy.........ITYmRTD |
Chain | Residue | Details |
A | GLN332-ASP346 | |
Functional Information from SwissProt/UniProt
Chain | Residue | Details |
A | TYR342 | |
Chain | Residue | Details |
A | GLU24 | |
A | ASP111 | |
Chain | Residue | Details |
A | HIS48 | |
A | ARG167 | |
A | ARG168 | |
A | ASP171 | |
A | TYR176 | |
A | TRP183 | |
A | ARG344 | |
A | ARG547 | |