6CBZ
Estrogen Receptor Alpha Ligand Binding Domain Y537S Mutant in Complex with Estradiol and GRIP Peptide
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue EST A 601 |
| Chain | Residue |
| A | MET343 |
| A | LEU346 |
| A | GLU353 |
| A | ARG394 |
| A | HIS524 |
| A | LEU525 |
| A | HOH807 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 601 |
| Chain | Residue |
| B | LEU408 |
| B | LEU409 |
| B | LEU410 |
| B | GLN414 |
| B | HOH701 |
| B | PHE337 |
| B | ASN407 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EST B 602 |
| Chain | Residue |
| B | LEU346 |
| B | GLU353 |
| B | ARG394 |
| B | HIS524 |
| B | LEU525 |
| B | HOH759 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE |
| Chain | Residue | Details |
| B | GLU353 | |
| B | ARG394 | |
| B | HIS524 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106 |
| Chain | Residue | Details |
| B | SER537 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| Chain | Residue | Details |
| B | CYS447 |
