Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue ADP A 1201 |
| Chain | Residue |
| A | GLY882 |
| A | GLU957 |
| A | LEU959 |
| A | SER963 |
| A | GLU966 |
| A | ARG1007 |
| A | ASN1008 |
| A | LEU1010 |
| A | ASP1021 |
| A | MG1202 |
| A | MG1203 |
| A | GLY884 |
| A | HIS885 |
| A | PHE886 |
| A | GLY887 |
| A | VAL889 |
| A | ALA906 |
| A | LYS908 |
| A | MET956 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1202 |
| Chain | Residue |
| A | ASN1008 |
| A | ASP1021 |
| A | ADP1201 |
| A | MG1203 |
| A | HOH1302 |
| A | HOH1317 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue MG A 1203 |
| Chain | Residue |
| A | ASP1003 |
| A | ASP1021 |
| A | ADP1201 |
| A | MG1202 |
| A | HOH1325 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue EDO A 1204 |
| Chain | Residue |
| A | LEU1108 |
| A | LEU1108 |
| A | LYS1109 |
| A | LYS1109 |
| A | GLY1111 |
| A | GLY1111 |
| A | ARG1113 |
| A | ARG1113 |
| A | PHE1134 |
| A | PHE1134 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1205 |
| Chain | Residue |
| A | GLN1055 |
| A | LYS1057 |
| A | HOH1316 |
| B | ARG59 |
| B | SER60 |
| B | GLN61 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue EDO B 201 |
| Chain | Residue |
| A | GLN1098 |
| B | ARG59 |
| B | ASP63 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 202 |
| Chain | Residue |
| B | VAL86 |
| B | ARG104 |
| B | SER106 |
| B | THR107 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 28 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGHFGKVElCrydpegdntgeq......VAVK |
| Chain | Residue | Details |
| A | LEU881-LYS908 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. YVHrDLAARNVLV |
| Chain | Residue | Details |
| A | TYR999-VAL1011 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10028","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00159","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"32750333","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphotyrosine; by autocatalysis","evidences":[{"source":"PubMed","id":"11909529","evidenceCode":"ECO:0000269"}]} |
