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6BWJ

Crystal structure of the TRPV2 ion channel in complex with RTx

Functional Information from GO Data
ChainGOidnamespacecontents
A0005216molecular_functionmonoatomic ion channel activity
A0005261molecular_functionmonoatomic cation channel activity
A0005262molecular_functioncalcium channel activity
A0005886cellular_componentplasma membrane
A0006811biological_processmonoatomic ion transport
A0009266biological_processresponse to temperature stimulus
A0009986cellular_componentcell surface
A0016020cellular_componentmembrane
A0030424cellular_componentaxon
A0032584cellular_componentgrowth cone membrane
A0042802molecular_functionidentical protein binding
A0044295cellular_componentaxonal growth cone
A0044297cellular_componentcell body
A0045773biological_processpositive regulation of axon extension
A0055085biological_processtransmembrane transport
A0070588biological_processcalcium ion transmembrane transport
A0090280biological_processpositive regulation of calcium ion import
A0098703biological_processcalcium ion import across plasma membrane
A0120162biological_processpositive regulation of cold-induced thermogenesis
B0005216molecular_functionmonoatomic ion channel activity
B0005261molecular_functionmonoatomic cation channel activity
B0005262molecular_functioncalcium channel activity
B0005886cellular_componentplasma membrane
B0006811biological_processmonoatomic ion transport
B0009266biological_processresponse to temperature stimulus
B0009986cellular_componentcell surface
B0016020cellular_componentmembrane
B0030424cellular_componentaxon
B0032584cellular_componentgrowth cone membrane
B0042802molecular_functionidentical protein binding
B0044295cellular_componentaxonal growth cone
B0044297cellular_componentcell body
B0045773biological_processpositive regulation of axon extension
B0055085biological_processtransmembrane transport
B0070588biological_processcalcium ion transmembrane transport
B0090280biological_processpositive regulation of calcium ion import
B0098703biological_processcalcium ion import across plasma membrane
B0120162biological_processpositive regulation of cold-induced thermogenesis
Functional Information from PDB Data
site_idAC1
Number of Residues10
Detailsbinding site for residue 6EU A 1001
ChainResidue
ATYR469
BLEU630
ASER470
ALEU473
AVAL504
AMET505
ATHR508
AARG515
ASER524
AILE531

site_idAC2
Number of Residues14
Detailsbinding site for residue 6EU B 803
ChainResidue
APHE549
ALEU623
ALEU629
ALEU630
BPHE465
BTYR469
BSER470
BLEU473
BMET505
BTHR508
BASN509
BTYR512
BARG515
BSER524

226707

PDB entries from 2024-10-30

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