Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
| D | 0008168 | molecular_function | methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | binding site for residue SAH A 1001 |
| Chain | Residue |
| A | PHE640 |
| A | ASP686 |
| A | VAL687 |
| A | GLY707 |
| A | PRO709 |
| A | LEU730 |
| A | ARG891 |
| A | SER892 |
| A | TRP893 |
| A | ASP641 |
| A | GLY642 |
| A | ILE643 |
| A | THR645 |
| A | SER663 |
| A | GLU664 |
| A | VAL665 |
| A | CYS666 |
| site_id | AC2 |
| Number of Residues | 17 |
| Details | binding site for residue SAH D 1001 |
| Chain | Residue |
| D | PHE640 |
| D | ASP641 |
| D | GLY642 |
| D | ILE643 |
| D | THR645 |
| D | SER663 |
| D | GLU664 |
| D | VAL665 |
| D | CYS666 |
| D | ASP686 |
| D | VAL687 |
| D | GLY707 |
| D | PRO709 |
| D | LEU730 |
| D | ARG891 |
| D | SER892 |
| D | TRP893 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | binding site for Di-nucleotide DG E 426 and PYO E 427 |
| Chain | Residue |
| D | SER708 |
| D | CYS710 |
| D | SER714 |
| D | ILE715 |
| D | VAL716 |
| D | GLU756 |
| D | VAL758 |
| D | ARG790 |
| D | ARG792 |
| D | ARG831 |
| D | THR832 |
| D | GLY890 |
| D | ARG891 |
| E | DT425 |
| E | DG428 |
| F | DG442 |
| F | DC443 |
| F | DA444 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | binding site for Di-nucleotide PYO E 427 and DG E 428 |
| Chain | Residue |
| D | SER708 |
| D | CYS710 |
| D | ASN711 |
| D | SER714 |
| D | VAL716 |
| D | ASN717 |
| D | PRO718 |
| D | GLU756 |
| D | VAL758 |
| D | ARG790 |
| D | ARG792 |
| D | THR834 |
| D | THR835 |
| D | GLY890 |
| D | ARG891 |
| E | DG426 |
| E | DT429 |
| F | DA440 |
| F | DC441 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | binding site for Di-nucleotide DG F 426 and PYO F 427 |
| Chain | Residue |
| A | SER708 |
| A | CYS710 |
| A | SER714 |
| A | ILE715 |
| A | VAL716 |
| A | GLU756 |
| A | VAL758 |
| A | ALA760 |
| A | ARG790 |
| A | ARG792 |
| A | THR832 |
| A | GLY890 |
| A | ARG891 |
| E | DG442 |
| E | DC443 |
| E | DA444 |
| F | DT425 |
| F | DG428 |
| site_id | AC6 |
| Number of Residues | 20 |
| Details | binding site for Di-nucleotide PYO F 427 and DG F 428 |
| Chain | Residue |
| A | ARG790 |
| A | ARG792 |
| A | THR835 |
| A | GLY890 |
| A | ARG891 |
| E | DA440 |
| E | DC441 |
| E | DG442 |
| F | DG426 |
| F | DT429 |
| A | SER708 |
| A | CYS710 |
| A | ASN711 |
| A | SER714 |
| A | VAL716 |
| A | ASN717 |
| A | PRO718 |
| A | GLU756 |
| A | VAL758 |
| A | ALA760 |
Functional Information from PROSITE/UniProt
| site_id | PS00094 |
| Number of Residues | 13 |
| Details | C5_MTASE_1 C-5 cytosine-specific DNA methylases active site. DlVigGsPCnDLS |
| Chain | Residue | Details |
| A | ASP702-SER714 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 556 |
| Details | Domain: {"description":"SAM-dependent MTase C5-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU01016","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU01016","evidenceCode":"ECO:0000255"},{"source":"PROSITE-ProRule","id":"PRU10018","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 18 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"17713477","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QRV","evidenceCode":"ECO:0007744"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"S-methylcysteine; by autocatalysis","evidences":[{"source":"UniProtKB","id":"O88508","evidenceCode":"ECO:0000250"}]} |
