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6BLW

Zinc finger Domain of WT1(+KTS form) with M342R Mutation and 17+1mer Oligonucleotide with Triplet GGT

Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue ZN A 501
ChainResidue
ACYS355
ACYS360
AHIS373
AHIS377

site_idAC2
Number of Residues4
Detailsbinding site for residue ZN A 502
ChainResidue
ACYS385
ACYS388
AHIS401
AHIS405

site_idAC3
Number of Residues4
Detailsbinding site for residue ZN A 503
ChainResidue
ACYS330
AHIS343
AHIS347
ACYS325

site_idAC4
Number of Residues4
Detailsbinding site for residue ZN A 504
ChainResidue
ACYS416
ACYS421
AHIS434
AHIS438

site_idAC5
Number of Residues5
Detailsbinding site for residue EDO A 505
ChainResidue
ALYS381
ASER393
AHIS397
BDT8
BDG9

site_idAC6
Number of Residues7
Detailsbinding site for residue EDO A 506
ChainResidue
AARG372
ASER393
AARG394
AHIS397
BDT8
BDG9
BHOH103

site_idAC7
Number of Residues7
Detailsbinding site for residue EDO A 507
ChainResidue
AARG366
AASP368
AARG372
BDA12
BDG13
BHOH108
CDC7

site_idAC8
Number of Residues5
Detailsbinding site for residue EDO A 508
ChainResidue
ALYS371
ALYS381
CDC5
CDC6
CHOH108

site_idAC9
Number of Residues2
Detailsbinding site for residue GOL A 509
ChainResidue
ALEU431
AVAL432

Functional Information from PROSITE/UniProt
site_idPS00028
Number of Residues23
DetailsZINC_FINGER_C2H2_1 Zinc finger C2H2 type domain signature. CaypgCnkrYfklshlqrHsrk..H
ChainResidueDetails
ACYS325-HIS347
ACYS355-HIS377
ACYS385-HIS405
ACYS416-HIS438

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues22
DetailsZN_FING: C2H2-type 3 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ATYR327-GLY349

site_idSWS_FT_FI2
Number of Residues24
DetailsZN_FING: C2H2-type 4 => ECO:0000255|PROSITE-ProRule:PRU00042
ChainResidueDetails
ALYS358-PRO382

site_idSWS_FT_FI3
Number of Residues2
DetailsSITE: Important for interaction with target DNA
ChainResidueDetails
AASP368
AGLN374

site_idSWS_FT_FI4
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ACYS388

227111

PDB entries from 2024-11-06

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