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6BC8

Crystal structure of Rev7-R124A/Rev3-RBM2 (residues 1988-2014) complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000785cellular_componentchromatin
A0001558biological_processregulation of cell growth
A0002208biological_processsomatic diversification of immunoglobulins involved in immune response
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005680cellular_componentanaphase-promoting complex
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005819cellular_componentspindle
A0005856cellular_componentcytoskeleton
A0006281biological_processDNA repair
A0006302biological_processdouble-strand break repair
A0007015biological_processactin filament organization
A0007094biological_processmitotic spindle assembly checkpoint signaling
A0008432molecular_functionJUN kinase binding
A0010628biological_processpositive regulation of gene expression
A0010718biological_processpositive regulation of epithelial to mesenchymal transition
A0010719biological_processnegative regulation of epithelial to mesenchymal transition
A0010944biological_processnegative regulation of transcription by competitive promoter binding
A0016035cellular_componentzeta DNA polymerase complex
A0033138biological_processpositive regulation of peptidyl-serine phosphorylation
A0035861cellular_componentsite of double-strand break
A0042177biological_processnegative regulation of protein catabolic process
A0042276biological_processerror-prone translesion synthesis
A0042772biological_processDNA damage response, signal transduction resulting in transcription
A0043247biological_processtelomere maintenance in response to DNA damage
A0043433biological_processnegative regulation of DNA-binding transcription factor activity
A0045830biological_processpositive regulation of isotype switching
A0045893biological_processpositive regulation of DNA-templated transcription
A0051301biological_processcell division
A0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
A0090090biological_processnegative regulation of canonical Wnt signaling pathway
A1901203biological_processpositive regulation of extracellular matrix assembly
A1904667biological_processnegative regulation of ubiquitin protein ligase activity
A2000042biological_processnegative regulation of double-strand break repair via homologous recombination
A2000048biological_processnegative regulation of cell-cell adhesion mediated by cadherin
A2000678biological_processnegative regulation of transcription regulatory region DNA binding
A2001034biological_processpositive regulation of double-strand break repair via nonhomologous end joining
Functional Information from PDB Data
site_idAC1
Number of Residues3
Detailsbinding site for residue SO4 A 301
ChainResidue
AASP113
ASER114
AHIS118

site_idAC2
Number of Residues2
Detailsbinding site for residue SO4 A 302
ChainResidue
ALYS190
ATHR191

site_idAC3
Number of Residues5
Detailsbinding site for residue ACT A 303
ChainResidue
BPRO1996
AASP66
ATHR67
APHE169
AHOH438

site_idAC4
Number of Residues2
Detailsbinding site for residue ACT A 304
ChainResidue
AGLN164
AHOH471

226707

PDB entries from 2024-10-30

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