Functional Information from GO Data
| Chain | GOid | namespace | contents |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | GLY34 |
| A | TYR36 |
| A | ARG46 |
| A | TYR49 |
| A | LEU89 |
| A | HIS91 |
| A | HOH421 |
| B | LEU99 |
| C | ARG507 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 302 |
| Chain | Residue |
| A | ASP92 |
| A | ILE93 |
| A | TYR94 |
| A | ALA95 |
| A | HOH402 |
| C | ARG395 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 303 |
| Chain | Residue |
| A | ARG24 |
| A | GLN160 |
| A | THR180 |
| A | HOH405 |
| A | HOH483 |
| B | GLN175 |
| B | SER176 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 304 |
| Chain | Residue |
| A | SER121 |
| A | ASP122 |
| A | GLU123 |
| A | HOH404 |
| B | PRO127 |
| B | LYS213 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue CO B 301 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | binding site for residue CO B 302 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 303 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| B | ARG98 |
| B | PHE103 |
| B | ARG104 |
| B | TYR106 |
| B | HOH402 |
| site_id | AC9 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | TYR33 |
| B | HIS35 |
| B | LEU99 |
| B | ALA100 |
| B | HOH401 |
| B | HOH406 |
| B | HOH520 |
| C | ARG507 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue PO4 B 306 |
| Chain | Residue |
| B | TYR27 |
| B | THR28 |
| B | TYR32 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 307 |
| Chain | Residue |
| B | TYR60 |
| B | GLN65 |
| B | HOH443 |
| B | HOH483 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue CO C 701 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue PO4 C 702 |
| Chain | Residue |
| C | ASP439 |
| C | THR440 |
| C | SER441 |
| C | HOH904 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 C 703 |
| Chain | Residue |
| C | THR393 |
| C | GLN394 |
| site_id | AD6 |
| Number of Residues | 6 |
| Details | binding site for residue PO4 C 704 |
| Chain | Residue |
| C | LYS518 |
| C | TYR545 |
| C | LYS550 |
| C | HOH897 |
| C | HOH898 |
| C | HOH901 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue PO4 C 705 |
| Chain | Residue |
| C | THR537 |
| C | HIS538 |
| site_id | AD8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 706 |
| Chain | Residue |
| C | GLN432 |
| C | ASN512 |
| C | THR513 |
| C | HOH851 |
| C | HOH860 |
| C | HOH873 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue GOL C 707 |
| Chain | Residue |
| C | VAL377 |
| C | GLY379 |
| C | GLU380 |
| C | TRP381 |
| C | ILE430 |
| C | SER477 |
| C | LEU514 |
| C | HOH845 |
| site_id | AE1 |
| Number of Residues | 4 |
| Details | binding site for residue GOL C 708 |
| Chain | Residue |
| C | PHE443 |
| C | GLN473 |
| C | GLN478 |
| C | VAL568 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue GOL C 709 |
| Chain | Residue |
| B | VAL11 |
| B | LYS13 |
| B | SER119 |
| B | THR120 |
| B | SER191 |
| C | SER420 |
| site_id | AE3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 710 |
| Chain | Residue |
| C | LYS505 |
| C | LEU506 |
| C | ARG507 |
| C | HOH802 |
| C | HOH803 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| C | LEU409-CYS414 | |
| site_id | PS00290 |
| Number of Residues | 7 |
| Details | IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH |
| Chain | Residue | Details |
| A | TYR192-HIS198 | |
| B | TYR198-HIS204 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| C | HIS413 | |
| C | ASP462 | |
| C | ALA557 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | BINDING: |
| Chain | Residue | Details |
| C | LYS529 | |
| Chain | Residue | Details |
| C | GLN432 | |
| Chain | Residue | Details |
| C | GLN473 | |
