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5Z02

Crystal structure of HIS6-tagged Mdm2 with nutlin-3a

Functional Information from GO Data
ChainGOidnamespacecontents
A0005634cellular_componentnucleus
A0043066biological_processnegative regulation of apoptotic process
A0051726biological_processregulation of cell cycle
Functional Information from PDB Data
site_idAC1
Number of Residues12
Detailsbinding site for residue NUT A 101
ChainResidue
AARG8
ATYR79
AHOH214
AHOH217
ALEU33
AGLY37
AMET41
AGLN51
AHIS52
APHE65
AVAL72
AHIS75

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues83
DetailsDomain: {"description":"SWIB/MDM2","evidences":[{"source":"PROSITE-ProRule","id":"PRU01273","evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

247536

PDB entries from 2026-01-14

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