5YZX

Crystal structure of E.coli LysU T146D mutant

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000049	molecular_function	tRNA binding
A	0000166	molecular_function	nucleotide binding
A	0000287	molecular_function	magnesium ion binding
A	0003676	molecular_function	nucleic acid binding
A	0004812	molecular_function	aminoacyl-tRNA ligase activity
A	0004824	molecular_function	lysine-tRNA ligase activity
A	0005524	molecular_function	ATP binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006412	biological_process	translation
A	0006418	biological_process	tRNA aminoacylation for protein translation
A	0006430	biological_process	lysyl-tRNA aminoacylation
A	0016020	cellular_component	membrane
A	0016874	molecular_function	ligase activity
A	0034605	biological_process	cellular response to heat
A	0036260	biological_process	RNA capping
A	0042803	molecular_function	protein homodimerization activity
A	0046872	molecular_function	metal ion binding
B	0000049	molecular_function	tRNA binding
B	0000166	molecular_function	nucleotide binding
B	0000287	molecular_function	magnesium ion binding
B	0003676	molecular_function	nucleic acid binding
B	0004812	molecular_function	aminoacyl-tRNA ligase activity
B	0004824	molecular_function	lysine-tRNA ligase activity
B	0005524	molecular_function	ATP binding
B	0005737	cellular_component	cytoplasm
B	0005829	cellular_component	cytosol
B	0006412	biological_process	translation
B	0006418	biological_process	tRNA aminoacylation for protein translation
B	0006430	biological_process	lysyl-tRNA aminoacylation
B	0016020	cellular_component	membrane
B	0016874	molecular_function	ligase activity
B	0034605	biological_process	cellular response to heat
B	0036260	biological_process	RNA capping
B	0042803	molecular_function	protein homodimerization activity
B	0046872	molecular_function	metal ion binding
C	0000049	molecular_function	tRNA binding
C	0000166	molecular_function	nucleotide binding
C	0000287	molecular_function	magnesium ion binding
C	0003676	molecular_function	nucleic acid binding
C	0004812	molecular_function	aminoacyl-tRNA ligase activity
C	0004824	molecular_function	lysine-tRNA ligase activity
C	0005524	molecular_function	ATP binding
C	0005737	cellular_component	cytoplasm
C	0005829	cellular_component	cytosol
C	0006412	biological_process	translation
C	0006418	biological_process	tRNA aminoacylation for protein translation
C	0006430	biological_process	lysyl-tRNA aminoacylation
C	0016020	cellular_component	membrane
C	0016874	molecular_function	ligase activity
C	0034605	biological_process	cellular response to heat
C	0036260	biological_process	RNA capping
C	0042803	molecular_function	protein homodimerization activity
C	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue B4P A 601

Chain	Residue
A	ALA217
A	ASP376
A	GLU421
A	ILE422
A	ASN424
A	ARG480
A	ILE491
A	CA602
A	CA603
A	CA604
A	ARG262
A	GLU264
A	SER267
A	ARG269
A	HIS270
A	ASN271
A	PHE274
A	MET276

---

site_id	AC2
Number of Residues	2
Details	binding site for residue CA A 602

Chain	Residue
A	GLU264
A	B4P601

---

site_id	AC3
Number of Residues	4
Details	binding site for residue CA A 603

Chain	Residue
A	GLU414
A	GLU421
A	ASN424
A	B4P601

---

site_id	AC4
Number of Residues	4
Details	binding site for residue CA A 604

Chain	Residue
A	ASP376
A	GLU414
A	GLU421
A	B4P601

---

site_id	AC5
Number of Residues	18
Details	binding site for residue B4P B 601

Chain	Residue
B	ARG262
B	GLU264
B	GLY265
B	SER267
B	ARG269
B	HIS270
B	ASN271
B	PHE274
B	MET276
B	GLU414
B	GLU421
B	ILE422
B	ASN424
B	ARG480
B	ILE491
B	CA602
B	CA603
B	CA604

---

site_id	AC6
Number of Residues	2
Details	binding site for residue CA B 602

Chain	Residue
B	GLU264
B	B4P601

---

site_id	AC7
Number of Residues	3
Details	binding site for residue CA B 603

Chain	Residue
B	GLU414
B	GLU421
B	B4P601

---

site_id	AC8
Number of Residues	2
Details	binding site for residue CA B 604

Chain	Residue
B	ASP376
B	B4P601

---

site_id	AC9
Number of Residues	16
Details	binding site for residue B4P C 601

Chain	Residue
C	ALA217
C	ARG262
C	ARG269
C	HIS270
C	ASN271
C	PHE274
C	MET276
C	GLU421
C	ILE422
C	ASN424
C	GLY477
C	ARG480
C	ILE491
C	CA602
C	CA603
C	CA604

---

site_id	AD1
Number of Residues	2
Details	binding site for residue CA C 602

Chain	Residue
C	ASP376
C	B4P601

---

site_id	AD2
Number of Residues	2
Details	binding site for residue CA C 603

Chain	Residue
C	GLU264
C	B4P601

---

site_id	AD3
Number of Residues	3
Details	binding site for residue CA C 604

Chain	Residue
C	GLU414
C	GLU421
C	B4P601

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Binding site: {}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine","evidences":[{"source":"PubMed","id":"18723842","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---