Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0046976 | molecular_function | histone H3K27 methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 501 |
| Chain | Residue |
| A | LYS211 |
| A | GLU238 |
| A | ASP279 |
| A | LYS284 |
| A | TYR365 |
| A | 73K502 |
| A | HOH650 |
| A | HOH827 |
| site_id | AC2 |
| Number of Residues | 15 |
| Details | binding site for residue 73K A 502 |
| Chain | Residue |
| A | TYR148 |
| A | ASN194 |
| A | LYS211 |
| A | LEU240 |
| A | ASP279 |
| A | LYS284 |
| A | THR285 |
| A | ARG287 |
| A | ASP310 |
| A | TYR365 |
| A | ARG367 |
| A | ARG414 |
| A | GOL501 |
| A | HOH809 |
| A | PHE97 |
Functional Information from PROSITE/UniProt
| site_id | PS00678 |
| Number of Residues | 15 |
| Details | WD_REPEATS_1 Trp-Asp (WD) repeats signature. LLSVskDhALRLWNI |
| Chain | Residue | Details |
| A | LEU206-ILE220 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 43 |
| Details | Repeat: {"description":"WD 1"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 43 |
| Details | Repeat: {"description":"WD 2"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 3"} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 41 |
| Details | Repeat: {"description":"WD 4"} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 37 |
| Details | Repeat: {"description":"WD 5"} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 40 |
| Details | Repeat: {"description":"WD 6"} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 33 |
| Details | Repeat: {"description":"WD 7"} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 360 |
| Details | Region: {"description":"Interaction with EZH2","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI9 |
| Number of Residues | 294 |
| Details | Region: {"description":"Required for interaction with the matrix protein MA of HIV-1"} |
| site_id | SWS_FT_FI10 |
| Number of Residues | 3 |
| Details | Modified residue: {"description":"N6-methyllysine; alternate","evidences":[{"source":"PubMed","id":"20974918","evidenceCode":"ECO:0000269"}]} |
