Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue NA A 501 |
Chain | Residue |
A | ASP60 |
A | HOH604 |
A | HOH634 |
A | HOH642 |
A | HOH646 |
A | HOH673 |
site_id | AC2 |
Number of Residues | 4 |
Details | binding site for residue CL A 502 |
Chain | Residue |
B | ARG41 |
A | THR74 |
A | ASN88 |
A | HOH687 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue CL A 503 |
Chain | Residue |
A | GLN18 |
A | MET36 |
A | SER37 |
A | HOH679 |
site_id | AC4 |
Number of Residues | 28 |
Details | binding site for residue GR7 B 201 |
Chain | Residue |
A | ARG8 |
A | ASP25 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
A | PRO81 |
A | VAL82 |
A | ILE84 |
A | HOH629 |
B | ARG8 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP29 |
B | ASP30 |
B | GLY48 |
B | GLY49 |
B | ILE50 |
B | PRO81 |
B | VAL82 |
B | ILE84 |
B | HOH304 |
B | HOH305 |
B | HOH308 |
site_id | AC5 |
Number of Residues | 1 |
Details | binding site for residue CL B 202 |
site_id | AC6 |
Number of Residues | 3 |
Details | binding site for residue CL B 203 |
Chain | Residue |
B | THR74 |
B | ASN88 |
B | HOH332 |
site_id | AC7 |
Number of Residues | 3 |
Details | binding site for residue CL B 204 |
Chain | Residue |
B | GLN18 |
B | MET36 |
B | SER37 |
site_id | AC8 |
Number of Residues | 5 |
Details | binding site for residue GOL B 205 |
Chain | Residue |
B | LYS55 |
B | VAL56 |
B | ARG57 |
B | HOH333 |
B | HOH357 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue ACT B 206 |
Chain | Residue |
B | PRO39 |
B | ARG41 |
B | TYR59 |
B | ASP60 |
B | HOH302 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA22-ILE33 | |