5W0R
Crystal structure of MBP fused activation-induced cytidine deaminase (AID) in complex with cacodylic acid
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008643 | biological_process | carbohydrate transport |
| A | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| A | 0015768 | biological_process | maltose transport |
| A | 0016020 | cellular_component | membrane |
| A | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| A | 0034219 | biological_process | carbohydrate transmembrane transport |
| A | 0034289 | biological_process | detection of maltose stimulus |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0042956 | biological_process | maltodextrin transmembrane transport |
| A | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| A | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0060326 | biological_process | cell chemotaxis |
| A | 1901982 | molecular_function | maltose binding |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008643 | biological_process | carbohydrate transport |
| B | 0015144 | molecular_function | carbohydrate transmembrane transporter activity |
| B | 0015768 | biological_process | maltose transport |
| B | 0016020 | cellular_component | membrane |
| B | 0030288 | cellular_component | outer membrane-bounded periplasmic space |
| B | 0034219 | biological_process | carbohydrate transmembrane transport |
| B | 0034289 | biological_process | detection of maltose stimulus |
| B | 0042597 | cellular_component | periplasmic space |
| B | 0042956 | biological_process | maltodextrin transmembrane transport |
| B | 0043190 | cellular_component | ATP-binding cassette (ABC) transporter complex |
| B | 0055052 | cellular_component | ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0060326 | biological_process | cell chemotaxis |
| B | 1901982 | molecular_function | maltose binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 2001 |
| Chain | Residue |
| B | HIS1056 |
| B | CYS1087 |
| B | CYS1090 |
| B | CAC2002 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue CAC B 2002 |
| Chain | Residue |
| B | CYS1090 |
| B | TYR1114 |
| B | ZN2001 |
| B | HOH2127 |
| B | HOH2161 |
| B | THR1027 |
| B | HIS1056 |
| B | TRP1084 |
| B | SER1085 |
| B | CYS1087 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue CA B 2003 |
| Chain | Residue |
| B | THR367 |
| B | ALA370 |
| B | HOH2155 |
| B | HOH2160 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ZN A 2001 |
| Chain | Residue |
| A | HIS1056 |
| A | CYS1087 |
| A | CYS1090 |
| A | CAC2002 |
| site_id | AC5 |
| Number of Residues | 9 |
| Details | binding site for residue CAC A 2002 |
| Chain | Residue |
| A | THR1027 |
| A | HIS1056 |
| A | TRP1084 |
| A | SER1085 |
| A | CYS1087 |
| A | CYS1090 |
| A | TYR1114 |
| A | ZN2001 |
| A | HOH2131 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue CA A 2003 |
| Chain | Residue |
| A | THR367 |
| A | ASN368 |
| A | ALA370 |
| A | ASP1045 |
| A | PHE1046 |
Functional Information from PROSITE/UniProt
| site_id | PS01037 |
| Number of Residues | 18 |
| Details | SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN |
| Chain | Residue | Details |
| B | PRO108-ASN125 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 56 |
| Details | Region: {"description":"Required for interaction with RNF126","evidences":[{"source":"PubMed","id":"23277564","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"UniProtKB","id":"P0ABF6","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"27258794","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphothreonine; by PKA","evidences":[{"source":"PubMed","id":"16387847","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 106 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Region: {"description":"Important for interaction with CTNNBL1","evidences":[{"source":"PubMed","id":"18722174","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine; by PKA","evidences":[{"source":"PubMed","id":"16387847","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18722174","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
