5VY4

Thermoplasma acidophilum 20S Proteasome using 200keV with image shift

Functional Information from GO Data

Chain	GOid	namespace	contents
0	0004175	molecular_function	endopeptidase activity
0	0004298	molecular_function	threonine-type endopeptidase activity
0	0005737	cellular_component	cytoplasm
0	0005839	cellular_component	proteasome core complex
0	0006511	biological_process	ubiquitin-dependent protein catabolic process
0	0010498	biological_process	proteasomal protein catabolic process
0	0019773	cellular_component	proteasome core complex, alpha-subunit complex
0	0030163	biological_process	protein catabolic process
1	0004175	molecular_function	endopeptidase activity
1	0004298	molecular_function	threonine-type endopeptidase activity
1	0005737	cellular_component	cytoplasm
1	0005839	cellular_component	proteasome core complex
1	0010498	biological_process	proteasomal protein catabolic process
1	0019774	cellular_component	proteasome core complex, beta-subunit complex
1	0030163	biological_process	protein catabolic process
A	0004175	molecular_function	endopeptidase activity
A	0004298	molecular_function	threonine-type endopeptidase activity
A	0005737	cellular_component	cytoplasm
A	0005839	cellular_component	proteasome core complex
A	0006511	biological_process	ubiquitin-dependent protein catabolic process
A	0010498	biological_process	proteasomal protein catabolic process
A	0019773	cellular_component	proteasome core complex, alpha-subunit complex
A	0030163	biological_process	protein catabolic process
B	0004175	molecular_function	endopeptidase activity
B	0004298	molecular_function	threonine-type endopeptidase activity
B	0005737	cellular_component	cytoplasm
B	0005839	cellular_component	proteasome core complex
B	0010498	biological_process	proteasomal protein catabolic process
B	0019774	cellular_component	proteasome core complex, beta-subunit complex
B	0030163	biological_process	protein catabolic process
C	0004175	molecular_function	endopeptidase activity
C	0004298	molecular_function	threonine-type endopeptidase activity
C	0005737	cellular_component	cytoplasm
C	0005839	cellular_component	proteasome core complex
C	0006511	biological_process	ubiquitin-dependent protein catabolic process
C	0010498	biological_process	proteasomal protein catabolic process
C	0019773	cellular_component	proteasome core complex, alpha-subunit complex
C	0030163	biological_process	protein catabolic process
D	0004175	molecular_function	endopeptidase activity
D	0004298	molecular_function	threonine-type endopeptidase activity
D	0005737	cellular_component	cytoplasm
D	0005839	cellular_component	proteasome core complex
D	0010498	biological_process	proteasomal protein catabolic process
D	0019774	cellular_component	proteasome core complex, beta-subunit complex
D	0030163	biological_process	protein catabolic process
E	0004175	molecular_function	endopeptidase activity
E	0004298	molecular_function	threonine-type endopeptidase activity
E	0005737	cellular_component	cytoplasm
E	0005839	cellular_component	proteasome core complex
E	0006511	biological_process	ubiquitin-dependent protein catabolic process
E	0010498	biological_process	proteasomal protein catabolic process
E	0019773	cellular_component	proteasome core complex, alpha-subunit complex
E	0030163	biological_process	protein catabolic process
F	0004175	molecular_function	endopeptidase activity
F	0004298	molecular_function	threonine-type endopeptidase activity
F	0005737	cellular_component	cytoplasm
F	0005839	cellular_component	proteasome core complex
F	0010498	biological_process	proteasomal protein catabolic process
F	0019774	cellular_component	proteasome core complex, beta-subunit complex
F	0030163	biological_process	protein catabolic process
G	0004175	molecular_function	endopeptidase activity
G	0004298	molecular_function	threonine-type endopeptidase activity
G	0005737	cellular_component	cytoplasm
G	0005839	cellular_component	proteasome core complex
G	0006511	biological_process	ubiquitin-dependent protein catabolic process
G	0010498	biological_process	proteasomal protein catabolic process
G	0019773	cellular_component	proteasome core complex, alpha-subunit complex
G	0030163	biological_process	protein catabolic process
H	0004175	molecular_function	endopeptidase activity
H	0004298	molecular_function	threonine-type endopeptidase activity
H	0005737	cellular_component	cytoplasm
H	0005839	cellular_component	proteasome core complex
H	0010498	biological_process	proteasomal protein catabolic process
H	0019774	cellular_component	proteasome core complex, beta-subunit complex
H	0030163	biological_process	protein catabolic process
I	0004175	molecular_function	endopeptidase activity
I	0004298	molecular_function	threonine-type endopeptidase activity
I	0005737	cellular_component	cytoplasm
I	0005839	cellular_component	proteasome core complex
I	0006511	biological_process	ubiquitin-dependent protein catabolic process
I	0010498	biological_process	proteasomal protein catabolic process
I	0019773	cellular_component	proteasome core complex, alpha-subunit complex
I	0030163	biological_process	protein catabolic process
J	0004175	molecular_function	endopeptidase activity
J	0004298	molecular_function	threonine-type endopeptidase activity
J	0005737	cellular_component	cytoplasm
J	0005839	cellular_component	proteasome core complex
J	0010498	biological_process	proteasomal protein catabolic process
J	0019774	cellular_component	proteasome core complex, beta-subunit complex
J	0030163	biological_process	protein catabolic process
K	0004175	molecular_function	endopeptidase activity
K	0004298	molecular_function	threonine-type endopeptidase activity
K	0005737	cellular_component	cytoplasm
K	0005839	cellular_component	proteasome core complex
K	0006511	biological_process	ubiquitin-dependent protein catabolic process
K	0010498	biological_process	proteasomal protein catabolic process
K	0019773	cellular_component	proteasome core complex, alpha-subunit complex
K	0030163	biological_process	protein catabolic process
L	0004175	molecular_function	endopeptidase activity
L	0004298	molecular_function	threonine-type endopeptidase activity
L	0005737	cellular_component	cytoplasm
L	0005839	cellular_component	proteasome core complex
L	0010498	biological_process	proteasomal protein catabolic process
L	0019774	cellular_component	proteasome core complex, beta-subunit complex
L	0030163	biological_process	protein catabolic process
M	0004175	molecular_function	endopeptidase activity
M	0004298	molecular_function	threonine-type endopeptidase activity
M	0005737	cellular_component	cytoplasm
M	0005839	cellular_component	proteasome core complex
M	0006511	biological_process	ubiquitin-dependent protein catabolic process
M	0010498	biological_process	proteasomal protein catabolic process
M	0019773	cellular_component	proteasome core complex, alpha-subunit complex
M	0030163	biological_process	protein catabolic process
N	0004175	molecular_function	endopeptidase activity
N	0004298	molecular_function	threonine-type endopeptidase activity
N	0005737	cellular_component	cytoplasm
N	0005839	cellular_component	proteasome core complex
N	0010498	biological_process	proteasomal protein catabolic process
N	0019774	cellular_component	proteasome core complex, beta-subunit complex
N	0030163	biological_process	protein catabolic process
O	0004175	molecular_function	endopeptidase activity
O	0004298	molecular_function	threonine-type endopeptidase activity
O	0005737	cellular_component	cytoplasm
O	0005839	cellular_component	proteasome core complex
O	0006511	biological_process	ubiquitin-dependent protein catabolic process
O	0010498	biological_process	proteasomal protein catabolic process
O	0019773	cellular_component	proteasome core complex, alpha-subunit complex
O	0030163	biological_process	protein catabolic process
P	0004175	molecular_function	endopeptidase activity
P	0004298	molecular_function	threonine-type endopeptidase activity
P	0005737	cellular_component	cytoplasm
P	0005839	cellular_component	proteasome core complex
P	0010498	biological_process	proteasomal protein catabolic process
P	0019774	cellular_component	proteasome core complex, beta-subunit complex
P	0030163	biological_process	protein catabolic process
Q	0004175	molecular_function	endopeptidase activity
Q	0004298	molecular_function	threonine-type endopeptidase activity
Q	0005737	cellular_component	cytoplasm
Q	0005839	cellular_component	proteasome core complex
Q	0006511	biological_process	ubiquitin-dependent protein catabolic process
Q	0010498	biological_process	proteasomal protein catabolic process
Q	0019773	cellular_component	proteasome core complex, alpha-subunit complex
Q	0030163	biological_process	protein catabolic process
R	0004175	molecular_function	endopeptidase activity
R	0004298	molecular_function	threonine-type endopeptidase activity
R	0005737	cellular_component	cytoplasm
R	0005839	cellular_component	proteasome core complex
R	0010498	biological_process	proteasomal protein catabolic process
R	0019774	cellular_component	proteasome core complex, beta-subunit complex
R	0030163	biological_process	protein catabolic process
S	0004175	molecular_function	endopeptidase activity
S	0004298	molecular_function	threonine-type endopeptidase activity
S	0005737	cellular_component	cytoplasm
S	0005839	cellular_component	proteasome core complex
S	0006511	biological_process	ubiquitin-dependent protein catabolic process
S	0010498	biological_process	proteasomal protein catabolic process
S	0019773	cellular_component	proteasome core complex, alpha-subunit complex
S	0030163	biological_process	protein catabolic process
T	0004175	molecular_function	endopeptidase activity
T	0004298	molecular_function	threonine-type endopeptidase activity
T	0005737	cellular_component	cytoplasm
T	0005839	cellular_component	proteasome core complex
T	0010498	biological_process	proteasomal protein catabolic process
T	0019774	cellular_component	proteasome core complex, beta-subunit complex
T	0030163	biological_process	protein catabolic process
U	0004175	molecular_function	endopeptidase activity
U	0004298	molecular_function	threonine-type endopeptidase activity
U	0005737	cellular_component	cytoplasm
U	0005839	cellular_component	proteasome core complex
U	0006511	biological_process	ubiquitin-dependent protein catabolic process
U	0010498	biological_process	proteasomal protein catabolic process
U	0019773	cellular_component	proteasome core complex, alpha-subunit complex
U	0030163	biological_process	protein catabolic process
V	0004175	molecular_function	endopeptidase activity
V	0004298	molecular_function	threonine-type endopeptidase activity
V	0005737	cellular_component	cytoplasm
V	0005839	cellular_component	proteasome core complex
V	0010498	biological_process	proteasomal protein catabolic process
V	0019774	cellular_component	proteasome core complex, beta-subunit complex
V	0030163	biological_process	protein catabolic process
W	0004175	molecular_function	endopeptidase activity
W	0004298	molecular_function	threonine-type endopeptidase activity
W	0005737	cellular_component	cytoplasm
W	0005839	cellular_component	proteasome core complex
W	0006511	biological_process	ubiquitin-dependent protein catabolic process
W	0010498	biological_process	proteasomal protein catabolic process
W	0019773	cellular_component	proteasome core complex, alpha-subunit complex
W	0030163	biological_process	protein catabolic process
X	0004175	molecular_function	endopeptidase activity
X	0004298	molecular_function	threonine-type endopeptidase activity
X	0005737	cellular_component	cytoplasm
X	0005839	cellular_component	proteasome core complex
X	0010498	biological_process	proteasomal protein catabolic process
X	0019774	cellular_component	proteasome core complex, beta-subunit complex
X	0030163	biological_process	protein catabolic process
Y	0004175	molecular_function	endopeptidase activity
Y	0004298	molecular_function	threonine-type endopeptidase activity
Y	0005737	cellular_component	cytoplasm
Y	0005839	cellular_component	proteasome core complex
Y	0006511	biological_process	ubiquitin-dependent protein catabolic process
Y	0010498	biological_process	proteasomal protein catabolic process
Y	0019773	cellular_component	proteasome core complex, alpha-subunit complex
Y	0030163	biological_process	protein catabolic process
Z	0004175	molecular_function	endopeptidase activity
Z	0004298	molecular_function	threonine-type endopeptidase activity
Z	0005737	cellular_component	cytoplasm
Z	0005839	cellular_component	proteasome core complex
Z	0010498	biological_process	proteasomal protein catabolic process
Z	0019774	cellular_component	proteasome core complex, beta-subunit complex
Z	0030163	biological_process	protein catabolic process

Functional Information from PROSITE/UniProt

site_id	PS00854
Number of Residues	48
Details	PROTEASOME_BETA_1 Proteasome beta-type subunits signature. VGItLkdAVIMATErrvtmenfimhkngk.KlfqidtytgmtiaGlvGD

Chain	Residue	Details
B	VAL4-ASP51

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	14
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"HAMAP-Rule","id":"MF_02113","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"7725107","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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