Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004518 | molecular_function | nuclease activity |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0004527 | molecular_function | exonuclease activity |
| A | 0008408 | molecular_function | 3'-5' exonuclease activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue PEG A 1401 |
| Chain | Residue |
| A | ASP23 |
| A | TYR25 |
| A | LYS999 |
| A | ILE1072 |
| A | VAL1073 |
| A | ASP1079 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | binding site for residue PEG A 1402 |
| Chain | Residue |
| A | PHE164 |
| A | GLY166 |
| A | ASN407 |
| A | HIS415 |
| A | HOH1520 |
| C | A19 |
| A | TYR136 |
| A | ARG139 |
| A | HIS160 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue PG4 A 1403 |
| Chain | Residue |
| A | THR924 |
| A | GLN926 |
| C | U11 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1404 |
| Chain | Residue |
| A | GLU327 |
| A | ASP331 |
| A | LYS392 |
| A | ASP397 |
| A | LEU399 |
| A | ARG400 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue MG C 101 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue PG4 C 102 |
| Chain | Residue |
| A | ARG71 |
| A | TYR72 |
| C | A18 |
| C | A19 |
| C | A20 |
| C | HOH222 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 61 |
| Details | Region: {"description":"RuvC-I","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 17 |
| Details | Region: {"description":"ARM","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 47 |
| Details | Region: {"description":"RuvC-II","evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 269 |
| Details | Region: {"description":"PAM-interacting domain (PI)","evidences":[{"source":"PubMed","id":"24529477","evidenceCode":"ECO:0000303"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Motif: {"description":"PAM substrate-binding","evidences":[{"source":"PubMed","id":"25079318","evidenceCode":"ECO:0000269"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | Active site: {"description":"For RuvC-like nuclease domain","evidences":[{"source":"PubMed","id":"24529477","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI7 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Proton acceptor for HNH nuclease domain","evidences":[{"source":"PubMed","id":"24529477","evidenceCode":"ECO:0000305"}]} |
| site_id | SWS_FT_FI8 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"24505130","evidenceCode":"ECO:0000269"}]} |
