5VVL
Cas1-Cas2 bound to full-site mimic with Ni
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004520 | molecular_function | DNA endonuclease activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006974 | biological_process | DNA damage response |
| A | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| A | 0017108 | molecular_function | 5'-flap endonuclease activity |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051607 | biological_process | defense response to virus |
| A | 0099048 | biological_process | CRISPR-cas system |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004520 | molecular_function | DNA endonuclease activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006974 | biological_process | DNA damage response |
| B | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| B | 0017108 | molecular_function | 5'-flap endonuclease activity |
| B | 0042802 | molecular_function | identical protein binding |
| B | 0042803 | molecular_function | protein homodimerization activity |
| B | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051607 | biological_process | defense response to virus |
| B | 0099048 | biological_process | CRISPR-cas system |
| C | 0003676 | molecular_function | nucleic acid binding |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004520 | molecular_function | DNA endonuclease activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006974 | biological_process | DNA damage response |
| C | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| C | 0017108 | molecular_function | 5'-flap endonuclease activity |
| C | 0042802 | molecular_function | identical protein binding |
| C | 0042803 | molecular_function | protein homodimerization activity |
| C | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0051607 | biological_process | defense response to virus |
| C | 0099048 | biological_process | CRISPR-cas system |
| D | 0003676 | molecular_function | nucleic acid binding |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0004520 | molecular_function | DNA endonuclease activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006974 | biological_process | DNA damage response |
| D | 0008821 | molecular_function | crossover junction DNA endonuclease activity |
| D | 0017108 | molecular_function | 5'-flap endonuclease activity |
| D | 0042802 | molecular_function | identical protein binding |
| D | 0042803 | molecular_function | protein homodimerization activity |
| D | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0051607 | biological_process | defense response to virus |
| D | 0099048 | biological_process | CRISPR-cas system |
| E | 0005515 | molecular_function | protein binding |
| E | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| E | 0099048 | biological_process | CRISPR-cas system |
| F | 0005515 | molecular_function | protein binding |
| F | 0043571 | biological_process | maintenance of CRISPR repeat elements |
| F | 0099048 | biological_process | CRISPR-cas system |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue NI A 401 |
| Chain | Residue |
| A | HIS208 |
| A | ASP221 |
| J | DG17 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue NI A 402 |
| Chain | Residue |
| A | LYS37 |
| H | DG1 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | binding site for residue NI B 401 |
| Chain | Residue |
| B | HIS208 |
| B | ASP221 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue NI C 401 |
| Chain | Residue |
| C | ASP244 |
| K | DA14 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue NI C 402 |
| Chain | Residue |
| C | GLU141 |
| C | HIS208 |
| C | ASP221 |
| J | DA58 |
| K | DG17 |
| site_id | AC6 |
| Number of Residues | 2 |
| Details | binding site for residue NI D 401 |
| Chain | Residue |
| D | HIS208 |
| D | ASP221 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | binding site for residue NI G 101 |
| Chain | Residue |
| C | LYS37 |
| G | DG1 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | binding site for residue NI J 101 |
| Chain | Residue |
| J | DG17 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue NI J 102 |
| Chain | Residue |
| J | DG8 |
| J | DG9 |
| site_id | AD1 |
| Number of Residues | 1 |
| Details | binding site for residue NI J 103 |
| Chain | Residue |
| J | DT7 |
| site_id | AD2 |
| Number of Residues | 2 |
| Details | binding site for residue NI J 104 |
| Chain | Residue |
| J | DG9 |
| J | DT10 |
| site_id | AD3 |
| Number of Residues | 1 |
| Details | binding site for residue NI J 105 |
| Chain | Residue |
| J | DG50 |
| site_id | AD4 |
| Number of Residues | 1 |
| Details | binding site for residue NI J 106 |
| Chain | Residue |
| J | DG5 |
| site_id | AD5 |
| Number of Residues | 1 |
| Details | binding site for residue NI J 107 |
| Chain | Residue |
| J | DG15 |
| site_id | AD6 |
| Number of Residues | 1 |
| Details | binding site for residue NI K 101 |
| Chain | Residue |
| K | DG17 |
| site_id | AD7 |
| Number of Residues | 2 |
| Details | binding site for residue NI K 102 |
| Chain | Residue |
| K | DC5 |
| K | DT6 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue NI K 103 |
| Chain | Residue |
| K | DG9 |
| K | NI104 |
| site_id | AD9 |
| Number of Residues | 3 |
| Details | binding site for residue NI K 104 |
| Chain | Residue |
| K | DG8 |
| K | DG9 |
| K | NI103 |
| site_id | AE1 |
| Number of Residues | 1 |
| Details | binding site for residue NI K 105 |
| Chain | Residue |
| K | DG7 |
| site_id | AE2 |
| Number of Residues | 1 |
| Details | binding site for residue NI K 106 |
| Chain | Residue |
| K | DG50 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue NI K 107 |
| Chain | Residue |
| C | PRO167 |
| K | DG15 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26503043","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5DS5","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"26503043","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 182 |
| Details | Region: {"description":"Sufficient for cleavage of ssRNA, ssDNA and Holliday junction DNA"} |
| Chain | Residue | Details |
