5VSI

CH1/Ckappa Fab mutant 15.1

Functional Information from GO Data

Chain	GOid	namespace	contents
L	0002250	biological_process	adaptive immune response
L	0002376	biological_process	immune system process
L	0005576	cellular_component	extracellular region
L	0005886	cellular_component	plasma membrane
L	0019814	cellular_component	immunoglobulin complex

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue SO4 H 301

Chain	Residue
H	TRP33
L	HIS93
H	TRP33
H	ARG57
H	ARG57
H	ASN59
H	ASN59
H	HOH436
H	HOH436
L	HIS93

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site_id	AC2
Number of Residues	8
Details	binding site for residue SO4 H 302

Chain	Residue
H	TRP33
H	TRP33
H	ASN52
H	ASN52
H	HOH436
H	HOH436
H	HOH491
H	HOH491

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 H 303

Chain	Residue
H	ARG38
H	GLN43
H	LYS63
H	ARG87
H	GLU89
H	HOH490
H	HOH544

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site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 H 304

Chain	Residue
H	SER169
H	GLN179
H	SER180
H	HOH523
H	HOH534
L	GLN159
L	LYS168

---

site_id	AC5
Number of Residues	6
Details	binding site for residue EDO H 305

Chain	Residue
H	ASN163
H	GLN200
H	THR201
H	HOH414
L	GLU160
L	VAL162

---

site_id	AC6
Number of Residues	6
Details	binding site for residue EDO L 301

Chain	Residue
H	LEU149
L	GLN159
L	THR177
L	HOH407
L	HOH409
L	HOH472

---

site_id	AC7
Number of Residues	3
Details	binding site for residue SO4 L 302

Chain	Residue
L	PRO58
L	SER59
L	HOH539

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site_id	AC8
Number of Residues	8
Details	binding site for residue EDO L 303

Chain	Residue
H	ASN55
H	ARG57
H	TYR107
L	TYR31
L	TYR33
L	TRP90
L	HOH404
L	HOH450

---

site_id	AC9
Number of Residues	6
Details	binding site for residue EDO L 304

Chain	Residue
L	GLN36
L	LYS38
L	LYS44
L	GLU80
L	ASP81
L	HOH503

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Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YICNVNH

Chain	Residue	Details
H	TYR202-HIS208
L	TYR191-HIS197

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