Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| A | 0016579 | biological_process | protein deubiquitination |
| B | 0004843 | molecular_function | cysteine-type deubiquitinase activity |
| B | 0016579 | biological_process | protein deubiquitination |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 16 |
| Details | binding site for residue 9QD A 601 |
| Chain | Residue |
| A | TYR224 |
| A | HIS456 |
| A | ASN460 |
| A | HIS461 |
| A | TYR465 |
| A | TYR514 |
| A | HOH761 |
| A | HOH801 |
| A | ASP295 |
| A | VAL296 |
| A | GLN297 |
| A | LEU406 |
| A | MET407 |
| A | ARG408 |
| A | PHE409 |
| A | LYS420 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue ACT A 602 |
| Chain | Residue |
| A | ASP295 |
| A | ASN418 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | binding site for residue 9QD B 601 |
| Chain | Residue |
| B | TYR224 |
| B | ASP295 |
| B | VAL296 |
| B | GLN297 |
| B | LEU406 |
| B | MET407 |
| B | ARG408 |
| B | PHE409 |
| B | LYS420 |
| B | HIS456 |
| B | ASN460 |
| B | HIS461 |
| B | TYR465 |
| B | TYR514 |
| B | GOL603 |
| B | HOH752 |
| B | HOH766 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue ACT B 602 |
| Chain | Residue |
| B | ASP295 |
| B | PHE409 |
| B | ASN418 |
| B | GOL603 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue GOL B 603 |
| Chain | Residue |
| B | MET292 |
| B | GLN293 |
| B | HIS294 |
| B | ASP295 |
| B | HIS461 |
| B | 9QD601 |
| B | ACT602 |
Functional Information from PROSITE/UniProt
| site_id | PS00972 |
| Number of Residues | 16 |
| Details | USP_1 Ubiquitin specific protease (USP) domain signature 1. GLknqGAtCYMNSlLQ |
| Chain | Residue | Details |
| A | GLY215-GLN230 | |
| site_id | PS00973 |
| Number of Residues | 18 |
| Details | USP_2 Ubiquitin specific protease (USP) domain signature 2. YiLhAVlvHsGdnhg..GHY |
| Chain | Residue | Details |
| A | TYR448-TYR465 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ARG239 | |
| B | ARG239 | |
| Chain | Residue | Details |
| A | PHE480 | |
| B | PHE480 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| A | PHE234 | electrostatic stabiliser |
| A | ARG239 | nucleofuge, nucleophile, proton acceptor, proton donor |
| A | PHE480 | proton acceptor, proton donor |
| A | ASN497 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 4 |
| Details | M-CSA 789 |
| Chain | Residue | Details |
| B | PHE234 | electrostatic stabiliser |
| B | ARG239 | nucleofuge, nucleophile, proton acceptor, proton donor |
| B | PHE480 | proton acceptor, proton donor |
| B | ASN497 | electrostatic stabiliser |
